Abstract
Anesthesiologists are frequently asked to care for patients at the extremes of age and size. These patient groups have unique features that require special consideration when formulating an anesthetic plan. The purpose of this chapter is to highlight alterations in physiology associated with these special populations, focusing in particular on how the altered physiology influences the behavior of anesthetic drugs. To translate this information into the clinical domain, the chapter aims to summarize dosing adjustments that account for body habitus (obese and morbidly obese) and age at both extremes (neonates and elderly).
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