Abstract
This chapter reviews the pharmacology of vasopressors and inotropes used commonly in acute care settings. It focuses on the pharmacodynamic properties of the drugs to a greater degree than their pharmacokinetic properties as most have short half-lives, are administered by continuous infusion, and are titrated to clinical effect. Clinicians know that when treating patients experiencing severe hypotension or cardiac failure, the effects of vasopressors and cardiotonic drugs depend on many associated factors, including acid-base status, temperature, blood volume, and concomitant drug administration. These factors are reviewed and recommendations are made for the rational selection and application of relevant vasopressors and inotropes.
Published Version
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