Abstract

The dynamics of clinical, hematological, biochemical and ultrasound parameters of patients with acute hepatitis of cats when using the drug «Heptral» for therapeutic purposes has been studied. The work was performed on 20 cats of different sexes and different ages, spontaneously ill with acute hepatitis. It was found that the clinical indicators of sick animals began to improve after 2–3 times intravenous administration of the drug at a dose of 30 mg per 1 kg of body weight once a day. Changes in hematological parameters after a 5-day course of treatment were characterized by a significant decrease in ESR, a decrease in the number of leukocytes. In the leukogram, a decrease in the relative content of stab and an increase in segmented neutrophils was noted. The concentration of hemoglobin and the content of erythrocytes increased within the reference values. Biochemical parameters were characterized by a significant decrease in the concentration of total and direct bilirubin, total protein, glucose and the activity of liver enzymes. However, by the end of the observation, the concentration of glucose, direct bilirubin and the activity of ALT and AST exceeded the levels of healthy animals.

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