Abstract
Purpose. To analyze the prevalence of retinopathy of prematurity (ROP) depending on the gestational age and solar activity; to predict the outcome of ROP in children born in different solar activity seasons. Material and methods. 229 case histories of premature infants born at children's hospital, Tambov within 2017–2019 were analyzed. They were divided into two groups: group I – children with retinopathy of prematurity (1, 2 and 3 degree), mean gestational age – 27.1 ± 2.3 weeks; mean birth weight 1008 ± 390 g and group II – premature infants without any retinopathy (pre retinopathy), mean gestational age 30.3 ± 2.12 weeks, mean gestational age 1614 ± 380 g. Also, all children were divided according to the birthday terms and periods of solar activity: winter, spring, summer, autumn. The disease outcome was taken into account in the children with ROP: children undergone laser coagulation (LC) and spontaneous regression. Results. The study revealed a strong direct relationship between the outcome of ROP and gestational age and seasonal solar activity. There were received the differences between ROP outcomes in children born in the period of increased and decreased insolation. Conclusion. The significant correlations were received: the greater the gestational age and birth weight is, the less likely the need for LC. A mathematical model for predicting the outcome of ROP was developed. Keywords: retinopathy of prematurity, solar activity, gestational age, screening, preventive measures, prediction.
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