Abstract

Purpose. To evaluate clinical efficacy and safety of micropulse cyclophotocoagulation (MP-CPC) in treatment patients with advanced and severe stages of primary open-angle glaucoma (POAG). Material and methods. Clinical study was carried out in 74 patients (74 eyes) with POAG aged 49 to 82 years. The advanced stage of glaucoma was detected in 35 eyes, the severe stage - in 39 eyes. The intraocular pressure (IOP) level before surgery varied from 23 to 36 mm Hg, averaging 29,6 ± 2,5 mm Hg. All patients underwent MP-CPC to standard technique using the Cyclo G6 Glaucoma Laser System the MicroPulse P3 glaucoma device (IRIDEX, USA). The observation period was 6 months. Results. All surgeries went without complications. The average IOP level on the 1st day after surgery was 21,1 ± 1,3 mm Hg. On the 1st day after surgery the more pronounced IOP decrease was revealed in patients with a dark (brown) iris color in comparison with a light (blue) iris. It was found that in periods to 6 months, the hypotensive effect of the surgery was more pronounced in patients of the age group under 60 years in comparison with the age group over 71 years. During the 1 year follow-up period, the IOP level was within normal values in 64 eyes (87%), averaging 20.9±1.2 mm Hg. Conclusion. MP-CPC is effective and safe operation to normalize IOP in most patients with advanced and severe stage of POAG with a follow-up period of 1 year. Keywords: micropulse cyclophotocoagulation, primary open-angle glaucoma, mild stage, moderate stage, intraocular pressure

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