Влияние терапевтического лазера синего спектра на зрительные функции и внутриглазное давление в норме и при субклиническом увеите

Abstract

Purpose. To study the frequency of occurrence of sluggish inflammation (BB) according to scanning laser ophthalmoscopy (SLO), identifying markers of BB using, incl., SLO; to investigate the effect of laser radiation (488 nm) blue diagnostic laser in scanning mode in healthy individuals, and low-energy blue therapeutic laser (450 nm) – on visual functions and the level of intraocular pressure (IOP) in patients with BB and primary open-angle glaucoma (POAG). Material and methods. The study included 394 patients who underwent laser scanning ophthalmoscopy; a group of 11 patients with a combination of sluggish uveitis and primary open-angle glaucoma (a 450 nm blue therapeutic laser session was performed) and 5 healthy individuals underwent standard ophthalmological examination, laser scanning ophthalmoscopy, computer threshold perimetry, autorefractometry and non-contact tonometry. Results. The presence of sluggish inflammation was determined according to the SLO data in 43 % of patients in this sample. Markers of sluggish inflammation were determined according to the data of the SLO and computer perimetry. In the group of patients with BB and POAG, significant improvements were noted: MD improvement by 67.7 %, IOP reduction by 10 %. With the selected modes of exposure to diagnostic blue laser (488 nm) in healthy individuals and low-intensity blue laser (450 nm) in the group of patients with BB and POAG, there was no negative effect on the field of vision (with «white on white» perimetry and blue-yellow perimetry) and IOP. Conclusions. 1. Scanning laser ophthalmoscopy can be effectively used for screening of sluggish inflammation with sufficient transparency of optical media. The frequency of occurrence of explosives in our sample was 43 %. 2. With the selected modes of exposure to blue-spectrum lasers, there was no negative effect on the field of vision and IOP both in the group of patients with a combination of BB and POAG (therapeutic laser 450 nm) and in the group of healthy individuals (diagnostic laser 488 nm) with a single exposure. 3. It is advisable to study the course effects of low-energy laser radiation in the blue spectrum in groups with explosives to determine the optimal accumulated dose.