World Federation Of Neurology Research Articles

Attitudes of neurologists, psychiatrists, and psychotherapists towards predictive testing for Huntington's disease in Germany.

Predictive testing for Huntington's disease (HD) in Germany is performed by genetic counsellors, neurologists, psychiatrists, and psychotherapists. In order to evaluate the attitudes of neurologists, psychiatrists, and psychotherapists in Germany towards predictive testing for HD, a postal questionnaire was sent to this group. Two German Bundesländer were chosen, Baden Württemberg (BW) and Niedersachsen (NS). Of 469 persons interviewed the response rate was 32.6%. The questionnaire consisted of 17 items assessing sociodemographic data, acquaintance with HD patients, lay organisations, attitudes towards genetic counselling, presymptomatic and prenatal DNA testing, and reproduction of persons at risk for HD. More than 70% of the subjects were well informed about predictive DNA testing but knowledge about the details of the test procedure, especially the World Federation of Neurology (WFN) and International Huntington Association (IHA)1 recommendations, was quite low (11.8%). Nevertheless, the majority would recommend predictive testing for HD although they anticipated problems for the probands. The majority of our respondents favoured psychological test and post-test counselling for those tested. Concerning reproduction, most subjects favoured prenatal testing or that persons at risk should refrain from having children. We found that the opinions of practitioners and at risk persons differed with respect to the predictive DNA test and, particularly, to prenatal testing. Therefore the testing procedure could be improved if practitioners were better informed about the DNA test in general and about the attitudes and wishes of their patients.

Evaluation of Clinical Criteria for Cluster Headache With Special Reference to The Classification of The International Headache Society

The diagnostic criteria issued by the International Headache Society (IHS) (1988) and those of the World Federation of Neurology (WFN) (1969) were evaluated vis-à-vis 163 consecutive cases of cluster headache diagnosed according to the criteria of Ekbom (1970). The agreement between the IHS and Ekbom criteria was very good (96.9%). The difference was explained by five patients who all lacked local autonomous symptoms and signs (conjunctival injection, lacrimation, etc.). At least one of these signs is mandatory according to the IHS and thus the patients escaped a definite diagnosis. Agreement between the WFN and Ekbom criteria was 84.0% (n = 163) and between the WFN and IHS criteria only 76.0% (n = 158).

World Federation of Neurology (WFN) Research Group on Huntington's Disease, Vancouver, 29 June to 2 July 1989

AIMS--To assess the role of Ki67 immunoreactivity in predicting the clinical progress of hydatidiform mole. METHODS--Tissue from 87 hydatidiform moles, 11 normal first trimester placentas, 11 normal term placentas and 17 spontaneous abortions were examined for expression of Ki67 antigen, using the monoclonal antibody MIB1. RESULTS--Ki67 immunoreactivity was significantly higher in the tissue from normal first trimester placentas than in that from normal term placentas and spontaneous abortions. Among the 87 patients with hydatidiform moles studied, 20 developed persistent gestational trophoblastic disease and required subsequent treatment. There was no statistically significant difference in the Ki67 index between the 20 patients who developed persistent disease and those who did not. CONCLUSION--Hydatidiform moles which give rise to persistent trophoblastic disease do not have a higher proliferative rate than those which do not. The Ki67 index is not useful for predicting the prognosis of molar pregnancies.

Ethical issues policy statement on Huntington's disease molecular genetics predictive test. International Huntington Association. World Federation of Neurology.

Ethical issues policy statement on Huntington's disease molecular genetics predictive test. International Huntington Association. World Federation of Neurology.

7th International Congress of Neuro-Ophthalmology and Neurogenetics of the World Federation of Neurology and 5th Meeting of the International Neuro-Ophthalmology Society

7th International Congress of Neuro-Ophthalmology and Neurogenetics of the World Federation of Neurology and 5th Meeting of the International Neuro-Ophthalmology Society

The Samuel T. Orton award for 1974 Presented by the Orton Society to Macdonald Critchley, M.D. Past President, World Federation of Neurology

The Samuel T. Orton award for 1974 Presented by the Orton Society to Macdonald Critchley, M.D. Past President, World Federation of Neurology

Dyslexia: Diagnostic and treatment findings and recommendations

Dr. Matejciek is Professor of Psychology, Postgraduate Medical Institute and Charles University, Prague, Czechoslovakia. He has published books in Czech and presented papers and lectures, in several languages, around the world. He is a member of the Research Group on Developmental Dyslexia and World Illiteracy of the World Federation of Neurology. He is best known to readers of the Bulletin of the Orton Society for his papers in its Volumes XV (1965) and XVIII (1968) and his extensive lecture tour of the U.S. in 1968, under the auspices of the Society, of whose Advisory Council he is a member. The current paper is adapted from chapters of a book in preparation for publication in Czechoslovakia, probably in 1972. —Editor

World Federation of Neurology

In the report (1962) of the study meeting on projections and nomenclature of the Problem Commission on Neuroradiology of the World Federation of Neurology (Milan, June, 1961) you describe the postero-anterior (inclined) projection of the skull as follows: “The forehead and nose touch the film, the median sagittal plane being perpendicular to the films. The orbito-meatal plane is also perpendicular to the film. The central ray is directed cranio-caudally to form an angle of 15 deg. with this plane (or about 25 deg. to the anthropological plane).”

Lipids and Leucodystrophies

Brain Lipids and Lipoproteins, and the Leucodystrophies Proceedings of the Symposium held in Rome, 1961, Organized by the World Federation of Neurology. Edited by Prof. J. Folch-Pi and Prof. H. Bauer. Pp. 213. (Amsterdam, London and New York: Elsevier Publishing Company, 1963.) n.p.

Brain Lipids and Lipoproteins, and the Leucodystrophies. Proceedings of the Neurochemistry Symposium, VII International Congress of Neurology, Rome, 1961. Organized by the Problem Commission of Neurochemistry of the World Federation of Neurology.

Brain Lipids and Lipoproteins, and the Leucodystrophies. Proceedings of the Neurochemistry Symposium, VII International Congress of Neurology, Rome, 1961. Organized by the Problem Commission of Neurochemistry of the World Federation of Neurology.

Report by the Commission of Neuroradiology (World Federation of Neurology)

Report by the Commission of Neuroradiology (World Federation of Neurology)

World Federation of Neurology. Problem Commission of Neuroradiology

World Federation of Neurology. Problem Commission of Neuroradiology