Social relationships within the workplace have been recognized to be vital for employee’s well-being. In this post Covid-19 era in Indonesia, major shifts in working arrangements have the potential to impact employees’ social relationships dynamics. Loneliness can emerge as a counterpoint to having positive social relationships. This non-experimental research employs a survey method to explore Workplace Loneliness (WL), Perceived Workplace Social Support (PWSS), and Happiness at Work (HAW) in post Covid-19 pandemic Indonesia. Statistical analysis is performed on responses from 201 participants representing employees with diverse working arrangements in Indonesian organizations, sampled using convenience sampling. Key research findings are as follows: 1) Comparing three employee groups with different working arrangements (WFH, WFO, and a blend of WFH and WFO) reveals no significant differences in WL levels, yet PWSS and HAW levels among the compared groups show significant variations. 2) WL has a significant negative association with HAW. 3) A moderation analysis is performed to reveal a significant negative interaction effect of WL and PWSS on HAW. These findings contribute to existing literature by shedding light on variables related to employee perceptions of social relationships and well-being in the workplace. This research delves into how employee perceptions of both negative (loneliness) and positive (perceived social support) aspects of social relationships correlate with workplace happiness. Additionally, this research highlights the post-Covid-19 disruption context in Indonesia, which impacted variations of employees’ working arrangements.