Abortion In Women Research Articles

The Dead Unborn, Postmortem Privacy Cases, and Abortion Rights.

The privacy of the dead is an interesting area of concern for bioethicists. There is a legal doctrine that the dead can't have privacy rights, but also a body of contrary law ascribing privacy rights to the deceased and kin in relation to the deceased. As women's abortion privacy is under assault by American courts and legislatures, the implications of ascribing privacy rights to embryos and fetuses is more important than ever. Caution is called for in this domain.

Aborted Women's Feelings and Experiences with Abortion: A Qualitative Study

Objective: This study aimed to reveal the feelings and experiences of women who had abortions based on their own experiences. Method: The qualitatively designed study was conducted with 11 women who applied to a Training and Research Hospital in Istanbul for abortion and met the inclusion criteria. The data were collected by the researchers with an 11-question participant information form and a semistructured interview form consisting of five questions. Results: The themes obtained from the research were determined as "The meaning of abortion", "The meaning attributed to the abortion decision", "Family and social support", "Community attitude" and "Attitude of healthcare professionals". Conclusion: Women who have had abortions are influenced by the perspective of society, religious values, and the approach of health professionals. There is a need to develop procedures that will positively affect women's abortion experiences.

Differential expression of immune checkpoints (OX40/OX40L and PD-1/PD-L1) in decidua of unexplained recurrent spontaneous abortion women

In this study, we aimed to investigate the expression of OX40, OX40L, PD-1 and PD-L1 in patients with unexplained recurrent spontaneous abortion (URSA) compared to normal pregnancies (NP). A total of 50 patients who were diagnosed with URSA and 41 NP were recruited to this study. Real-time polymerase chain reaction (RT-PCR) was used to determine the expression of OX40, OX40L, PD-1 and PD-L1 in decidual tissues; Immunohistochemistry (IHC) was conducted to characterize the distribution of the involved genes in decidual tissues; Double immunofluorescence staining was used to prove the localization of the involved genes in decidual tissues. The concentrations of OX40L and PD-L1 in plasma were measured with enzyme-linked immunosorbent assay (ELISA). The expression of OX40L in the decidua of URSA patients was significantly increased compared to that in the NP group, while the expression of PD-L1 in the URSA group was decreased compared to that in the NP group. Both proteins are localized in the decidual stroma as analyzed by double immunofluorescence staining. The staining results were confirmed at the mRNA level of decidual tissues, while the mRNA level of peripheral blood showed no significant difference. In conclusion, the results suggest that decidual stromal cells may promote the interaction with OX40 on T cells by upregulating the expression of OX40L and reduce the interaction with PD-1 on T cells by downregulating the expression of PD-L1 in URSA patients, which may interfere with the immune tolerance of the maternal-fetal interface, leading to poor pregnancy outcomes.

Relationship Between Fetal Life Rights and Women's Abortion Rights

Starting from the attitudes of different historical periods and countries towards the right to fetal life, this article focuses on analyzing the conflict and reconciliation between the right to fetal life and womens right to abortion. At the same time, this article also compares the different provisions on the determination of fetal life in legislation of countries such as the United States, Germany, and China, and analyzes the different manifestations of the conflict between the right to fetal life and womens abortion rights within and outside the region. Finally, based on the current conflict situation, root causes, and excellent practices abroad, some suggestions are proposed for abortion legislation in China.

Evaluation The Sero-Prevalence of Cytomegalovirus Infection among Abortion Women in Baqubah city

Evaluation The Sero-Prevalence of Cytomegalovirus Infection among Abortion Women in Baqubah city

Using Antibody rapid test, RT-qPCR, and RFLP/PCR for detecting Toxoplasma gondii in the placenta of abortion women and determining the genotype in Maysan province, Iraq .

Toxoplasma gondii is one of the obligatory intracellular protozoan parasites that are important and widespread in all developing or developed countries. It infects all nucleated cells of warm-blooded animals. This study used the lateral flow immunoassay (LFIA), real-time quantitative polymerases chain reactions (RT-qPCR) for detecting the T. gondii in blood and placental tissues, in addition to the restriction fragment length polymorphism (RFLP) technique to determine the genotypes/strains of T. gondii in Maysan province. The study included 40 participating women, distributed as 22 aborted women and 18 without abortion. The LFIA detected that the seropositive rate of anti-T. gondii IgG is 38.9 % and with the using RT-qPCR technique, the infection rate is 10 % and 0.0 % among placenta and sera. it also, showed that 85.7 % of all T. gondii infections are found in aborted women, compared with 14.3 % without abortion. In contrast, it showed that 63.6 % of T. gondii seronegative are women without abortion, compared to 36.4 % among aborted women. The PCR-RFLP technique has identified the main three genotypes “I, II, and III” of T. gondii in Ammara city, and showed that genotype "I" is the most frequent at 50% (6/12) than genotypes II, 4/12 (33.33 %), and III, 2/12 (16.67 %).

Association between female circulating heavy metal concentration and abortion: a systematic review and meta-analysis.

This study aimed to evaluate the association between blood heavy metal (zinc (Zn), copper (Cu), lead (Pb), and cadmium (Cd)) concentrations and spontaneous abortion (SA) and recurrent pregnancy loss (RPL) and explore the possible endocrine dysfunction associated with it. A literature search was performed in the PubMed, Embase, Cochrane Library, and Web of Science databases up to April 2023. The overall effects were expressed as the standard mean difference (SMD). Subgroup analysis was performed according to the type of abortion (SA or RPL). Stata 16.0 was utilized for data analysis. Based on the integrated findings, abortion women showed significantly lower Zn (SMD = -1.05, 95% CI: -1.74 to -0.36, p = 0.003) and Cu concentrations (SMD = -1.42, 95% CI: -1.97 to -0.87, p <0.001) and higher Pb (SMD = 1.47, 95% CI: 0.89-2.05, p <0.001) and Cd concentrations (SMD = 1.15, 95% CI: 0.45-1.85, p = 0.001) than normal pregnant women. Subgroup analysis showed that Zn and Cu deficiency and Cd and Pb exposure were significantly (p <0.05) associated with RPL, whereas Cu deficiency and Cd and Pb exposure were significantly (p <0.05) associated with SA. Zn and Cu deficiencies and Pb and Cd exposure were associated with abortion. Endocrine dysfunction, such as insulin resistance, vitamin D insufficiency, and abnormal thyroid and sex hormone concentrations, is thought to be involved in heavy metal-related abortion.

Association Between Toxoplasmosis Infection and Human Insulin In Pregnant and Aborted Women

Background : People with compromised immune systems are more likely to get infected with the opportunistic parasite Toxoplasma gondii than healthy individuals. Diabetes and toxoplasmosis are two conditions that are rather prevalent in Iraq. Objective : human insulin was the major objective of this study, along with determining the frequency of anti- T. gondii IgG antibodies in pregnant and abortion. In addition to this, establish a connection of (RBS) and (HbA1c). Methods : The investigation was in Al-Qadisiyah. The term for collecting was from the November 2022 to the end of February 2023. where specimens were collected from the Maternity and Children's Teaching Hospital, 350 serum samples that were collected from pregnant, and abortion women. The healthy samples that served as a control group50 samples,. Both the ELISA technique and the Toxo Rapid Diagnostic Test (Cassette) were used to analyze the samples in order to determine the levels of human insulin present in pregnant and abortion women. Also measures (HbA1c) and (RBS). Results : the Results According Cassette the 350 samples, only 130 (43.3%) positive, whereas 170 (56.7%) negative. Using ELISA, anti-T. gondii IgG was present in 90 (69.2%) of the women from 170 positive cassette. ELISA was also used to assess of human insulin that was present in order to get a better understanding of the role that toxoplasmosis plays in the development of diabetes. Patients with diabetes had considerably higher levels of human insulin (22.83 ± 13.91) when compared to patients with toxoplasmosis alone and healthy controls Conclusion : T. gondii is more prevalent among pregnant women and abortions. Diabetes and toxoplasmosis have been shown to have a close connection, according to research. Our hypothesis is that toxoplasmosis provides the way for diabetes, and diabetes paves the way for toxoplasmosis. Toxoplasmosis is more likely to develop in people with diabetes since the disease lowers the immune response.

LincRNA RP24-315D19.10 promotes endometrial decidualization via upregulation of hnRNPA2B1

Decidualization is a critical process for successful pregnancy. Disorders in this process are tightly associated with adverse pregnancy outcomes including spontaneous abortion. However, the potential molecular mechanisms of lncRNAs underlying this process are yet to be fully elucidated. In this study, we utilized RNA sequencing (RNA-seq) to identify differentially expressed lncRNAs during endometrial decidualization with a pregnant mouse model. Based on RNA-seq analysis, weighted gene co-expression network analysis (WGCNA) was performed to construct the lncRNA-mRNA co-expression network and to identify decidualization-associated hub lncRNAs. Through comprehensive screening and validation, we identified a novel lncRNA, RP24-315D19.10 and studied its function in primary mouse endometrial stromal cells (mESCs). lncRNA RP24-315D19.10 was highly expressed during decidualization. Knockdown of RP24-315D19.10 significantly inhibited mESCs decidualization in vitro. Mechanistically, RNA pull-down and RNA immunoprecipitation assays indicated that cytoplasmic RP24-315D19.10 could bind to hnRNPA2B1, thereby upregulating hnRNPA2B1 expression. Site-directed mutagenesis followed by biolayer interferometry analysis additionally illustrated that hnRNPA2B1 protein specifically bound to the ~-142ccccc~-167 region of the RP24-315D19.10 sequence. hnRPA2B1 deficiency impairs mESCs decidualization in vitro and we found that the inhibition in decidualization caused by RP24-315D19.10 knockdown was rescued by hnRNPA2B1 overexpression. Moreover, the expression of hnRNPA2B1 in spontaneous abortion women with deficient decidualization was significantly lower than that in healthy individuals, suggesting that hnRNPA2B1 may be involved in the development and progression of spontaneous abortion caused by decidualization failure. Collectively, our study indicates RP24-315D19.10 is a critical regulator for endometrial decidualization and RP24-315D19.10-regulated hnRNPA2B1 might be a new mark of decidualization-related spontaneous abortion.

Exploring the Development of Women's Abortion Rights in the United States

Exploring the Development of Women's Abortion Rights in the United States

The Impact of Socioeconomic Status Differences on Women's Abortion Rights in the United States

This paper attempts to address the abortion dilemma faced by women of different social statuses after Roe v. Wade. This paper argues that socioeconomic status can influence the impact of abortion on women. Socioeconomic status differences in medical protection and, family and social status all affect a woman's willingness to have an abortion and her ability to choose one. Although the law cannot guarantee reproductive justice for low SES women, this paper suggests that investing in the education of low SES women, including sex education and health education, to build human capital for them can achieve their abortion rights in the long run. In addition, the paper argues that more investment in education for women may also lead to a difference in economic level.

Assessing the effects of duration of birth interval on adverse pregnancy outcomes in sub-Saharan Africa: a propensity score-matched analysis

ObjectivesUnlike high-income countries, sub-Saharan African countries have the highest burden of adverse pregnancy outcomes such as abortion, stillbirth, low birth weight and preterm births. The WHO set optimal birth spacing...

Problems in Law Enforcement of The Crime of Women's Abortion

The purpose of this study is to examine the implementation of abortion in Indonesia, especially for women who are victims of rape. The research method used is normative juridical. The results showed that a person could have an abortion when pregnancy occurs due to rape which can cause psychological trauma with the condition that the abortion is carried out before six weeks of pregnancy, calculated from the first day of the last menstruation. It is still found that abortions are carried out when the pregnancy is more than six weeks old. Not a few of those who carry out abortions are sentenced to criminal penalties, can say that the application of legal protection guaranteed by the law is far from perfect, especially law enforcement that is less partial to rape victims who choose the abortion route does not reflect the sense of justice, certainty and benefit be a legal goal. Therefore, legal protection for abortionists who are victims of rape must consider the best interests of the victims, and this can be realized when the Government carries out its obligations to protect and prevent abortions.

Study some biochemical and blood criteria in aborted women with toxoplasmosis in Tikrit city

In Current study have iso blood samples was collected,150 of blood samples inclouding 100 samples of aborted women, and 50 blood samples of control group and also the studies inclouded Biochemistry comparison for some Biochemistry comparision for some Biochemistrial standards in serum of abortion women and from these standards included total protein, Calcium ions, urea, glutamate pyruvata trans amines and regulation of glutamate oxalocytic trans amines (GOT and GPT). the study showed corporeal differences in the probability level p≥0.05 that rising concentration of GOT, GPT magnitude (36.2±78.9 u\L), (16.7±70.4u/L) on pectively, calcium concentration lowered to (o.570 mg\dl±7.204), and the study included in corporeal differences in the level of probability p≥0.05 of total protein magnituded by(8.751± o.414 Mg/dl),urea by (25.o8±6.25 Mg/dl) and also the study included some blood tests, and the samples groveled to blood test in cluted the size of packet cell volume (p.c.v) and calculate the number of the differential leuco cyst (D.L.C), and also examin happened for blood factionals and raisi facter RH, the Results showed corporeal variances in the level of probability p≤0.o5 with respect to p.c.v where the level lowered in the blood samples of abortion women by (31.01±2.05) but regarding differential number for Leuco cyst, current results showed rising ratio of eosinophile while blood corpuscles . and rising in the level of probability p≤0.05 by (5.83±13.52) and also lympho cyst by (51.17±8.57), monocyte by (5.30 ±14.68) ,and also dosent observe any corporeal variances differences on the level of probability p≥0.05 with Base philis (23.23±8.31), the current study the current study does not record any corporeal differences concurring blood factions and raise factor .

Study of IL-27 Polymorphisms with Chemical Factor in Abortion Women

Study of IL-27 Polymorphisms with Chemical Factor in Abortion Women

Immunological Detection of Cytomegalovirus and Bacterial Vaginosis Associated with Trichomonas vaginalis in Women with Miscarriage

Miscarriage is a complicated pregnancy and known as a spontaneous ending of pregnancy itself before the baby has attained a level of viability. Miscarriages may be sporadic or recurrent. A total of (113) a high vaginal swabs and serum was collected. According to sample size, samples from aborted women were obtained from hospitals in Maysan Governorate, Iraq (cervical swabs and serum) in the obstetric and gynecology outpatients department during period from November 2020 to May 2021. Some variables were been investigated in accurate study like age, education, residences and diseases and others. The SPSS version (23) is used for a statistical analysis, and a p-value of (0.05) was considered statistically significant. The aim of the study is immunological detection of IgM and IgG cytomegalovirus in blood of infected women suffering with Trichomonas vaginalis and bacterial vaginosis. Associated between cytomegalovirus, T. vaginalis and bacterial vaginosis in a abortion women.

Abortion decision-making process trajectories and determinants in low- and middle-income countries: A mixed-methods systematic review and meta-analysis.

SummaryBackgroundAbout 45.1% of all induced abortions are unsafe and 97% of these occur in low- and middle-income countries (LMICs). Women's abortion decisions may be complex and are influenced by various factors. We aimed to delineate women's abortion decision-making trajectories and their determinants in LMICs.MethodsWe searched Medline, EMBASE, PsychInfo, Global Health, Web of Science, Scopus, IBSS, CINAHL, WHO Global Index Medicus, the Cochrane Library, WHO website, ProQuest, and Google Scholar for primary studies and reports published between January 1, 2000, and February 16, 2021 (updated on June 06, 2022), on induced abortion decision-making trajectories and/or their determinants in LMICs. We excluded studies on spontaneous abortion. Two independent reviewers extracted and assessed quality of each paper. We used “best fit” framework synthesis to synthesise abortion decision-making trajectories and thematic synthesis to synthesise their determinants. We analysed quantitative findings using random effects model. The study protocol is registered with PROSPERO number CRD42021224719.FindingsOf the 6960 articles identified, we included 79 in the systematic review and 14 in the meta-analysis. We identified nine abortion decision-making trajectories: pregnancy awareness, self-reflection, initial abortion decision, disclosure and seeking support, negotiations, final decision, access and information, abortion procedure, and post-abortion experience and care. Determinants of trajectories included three major themes of autonomy in decision-making, access and choice. A meta-analysis of data from 7737 women showed that the proportion of the overall women's involvement in abortion decision-making was 0.86 (95% CI:0.73–0.95, I2 = 99.5%) and overall partner involvement was 0.48 (95% CI:0.29–0.68, I2 = 99.6%).InterpretationPolicies and strategies should address women's perceptions of safe abortion socially, legally, and economically, and where appropriate, involvement of male partners in abortion decision-making processes to facilitate safe abortion. Clinical heterogeneity, in which various studies defined “the final decision-maker” differentially, was a limitation of our study.FundingNuffield Department of Population Health DPhil Scholarship for PL, University of Oxford, and the Medical Research Council Career Development Award for MN (Grant Ref: MR/P022030/1).

Seroprevalence of cytomegalovirus antibodies among aborted women in Ibb city-Yemen

Abortion is one of the most common health problems in the world, its causes vary, and some of them are viral. Cytomegalovirus (CMV) is one of the causes of abortion. So, this study aims to investigate the seroprevalence of CMV antibodies among aborted women. This study was a cross-sectional study conducted in Ibb city-Yemen. Serum samples were collected between September 2021 to April 2022. The serum samples were analyzed for IgG and IgM antibodies to CMV by Electro-Chemiluminescence Immunoassay (ECLIA). Overall, 150 aborted women were enrolled. Amongst these cases, 148 out of 150 (98.67%) were positive for CMV IgG antibodies. Additionally, 11 out of 150 (7.33%) of the samples were positive for CMV IgM antibodies. The CMV IgG seroprevalence was not significantly influenced by age, residence, education level, socioeconomic status and abortion time. In addition, the CMV IgM seroprevalence was significantly associated with education level, socioeconomic status and abortion time. In conclusion, the low rate of CMV IgM and a high proportion of CMV IgG for most major of abortion women in this study suggest that CMV may not be the common factor leading to abortion.

Seroprevalence of Cytomegalovirus, Rubella, Herpes Simplex Type II and Chlamydia trachomatis in Pregnant and Abortion Women in Tikrit City

Aim of this study was to assess the Seroprevalence of Cytomegalovirus (CMV), Rubella, Herpes simplex II and Chlamydia trachomatis infections among pregnant and abortion women. This study was performed on 210 women who attended the gynecological consultative clinic in Salah El-Din general hospital during November 2021 until the end of march 2022.the sera samples were tested by ELISA assay for detection of specific IgG and IgM antibodies. Overall Seroprevalence was 10%, 5.7%, 3.3%, 1.9% of IgG for CMV, Rubella, Chlamydia trachomatis and HSV II respectively while IgM was 3.8%, 2.8%, and 1% for the last two respectively.

Toxoplasma gondii Infection and Threatened Abortion in Women from Northern Peru.

Introduction Toxoplasma gondii infection can cause important complications during pregnancy. Threatened abortion may be a late indicator for infection in settings with high prevalence of toxoplasmosis. We aimed to determine the association between T. gondii infection and threatened abortion in women from northern Peru. Methods We conducted a secondary analysis of a cross-sectional study in pregnant women from a hospital and a rural community in Lambayeque, Peru. Exposure variable was serological diagnosis of toxoplasmosis, defined as the demonstration of either IgM or IgG antibodies against T. gondii. Outcome variable was threatened abortion, defined as the diagnosis of bloody vaginal discharge or bleeding during the first half of pregnancy. Prevalence ratios were estimated in simple and multiple regression analyses. Results Of 218 pregnant women, 35.8% presented positive serology for T. gondii and 14.7% had threatened abortion in their current pregnancy. Pregnant women with positive T. gondii infection had 2.45-fold higher frequency of threatened abortion (PR: 2.45, 95% CI: 1.15-5.21). In addition, the frequency of threatened abortion decreased by 9% for each additional year of age (PR: 0.91, 95% CI: 0.86-0.97). A previous history of threatened abortion also showed a higher frequency of threatened abortion (PR: 5.22, 95% CI: 2.45-11.12). Conclusions T. gondii infection is associated with threatened abortion. An early age of pregnancy and a previous history of abortion are also associated with this condition.