Women Of Various Age Groups Research Articles

Histopathological study of ovarian tumors in a tertiary care center

Introduction: Ovary is a complex structure and its neoplasms show a wide spectrum of histological types and clinical behavior. The present study was done with the aim of studying the histopathological pattern of ovarian tumors in women of various age groups. Ovarian tumors represent about 30% of all cancers of the female genital system. Ovarian tumor is the seventh leading cause of cancer death. Ovarian tumors are often difficult to detect until they are advanced in stage or size, as symptoms are vague and insidious. An accurate and early diagnosis of malignant lesions will go a long way in the optimal management of these cases. Aims and Objectives: To determine the frequency of different histological types of ovarian tumors in a tertiary care center. Materials and Methods: This was a retrospective study included 150 cases of histopathologically proven ovarian tumors, reported in the Sree Mookambika Institute of medical sciences, over a one and half year period (January 2018 to June 2019). These were classified according to the WHO classification of ovarian tumors. Clinical presentation of the patients was analyzed from archived case records. Results: Of 150 cases of ovarian tumors, 138 masses were unilateral (92%) and 12 were bilateral (8%). Benign neoplastic lesions were 58.7%, and malignant was 2%.In benign neoplastic, the most common neoplasm was serous cystadenoma followed by mucinous cystadenoma In malignant, the current study had 2 cases of mucinous cystadenoma with borderline malignancy and 1 case was serous papillary cystadenocarcinoma Conclusion: A more detailed prospective study include genetic profiling, to establish the reason for this low incidence of malignant lesions

Оценка психологических особенностей, состава тела и статуса фактического питания у женщин разных возрастных групп с нарушениями пищевого поведения

Оценка психологических особенностей, состава тела и статуса фактического питания у женщин разных возрастных групп с нарушениями пищевого поведения

The comparative analysis of body weight of women in various age groups with different physical activity level

The authors evaluated the body weight and daily energy expenditure of women performing occupational activity under different conditions: office work, outdoor work and mixed conditions (mixed office and outdoor work). The women were stratified into following age groups: 25-30, 30-35, 35-40 and 40 years and older. The significant differences were observed in energy expenditure between women worked under mixed conditions and performed outdoor work and women engaged in the office work (22,8% and 50,9%, respectively) as well as differences were noted between second and third groups (23,0%). The different working conditions exerted the influence upon the body weight. According to age groups, weight gain was lower in women with higher physical activity. There were significant differences in portion of persons with normal body weight in elder age groups. The increase of portion of persons with obesity was less significant.

Regularities in the Dynamics of Age-Specific Indicators of Mortality from Malignant Neoplasms in Russian Population

Every year, more than 600 000 (617 177 in 2017) new cases of malignant neoplasms (MNPs) are registered in Russia, and annual cancer mortality exceeds 290 000 (290 622 in 2017). Malignant tumors rank second (15.9% in 2017) after cardiovascular mortality (48.8% in 2017), while success in their treatment elevated MNPs to first place in some economically developed countries. In many administrative territories of Russia, the proportion of MNP in the total mortality is 20–25%. MNPs are mass noncommunicable diseases that are most strongly associated with the age structure of the population. More than 70% (72.59%) of patients and ~80% (79.07%) of deaths in Russia are registered in patients at retirement age. From the 1960 census to the present, the proportion of people of retirement age group in the age structure of the population has doubled, which, of course, affected the MNP incidence and mortality rate. The system of population-based cancer registers created in the 1990s contributed to the improved reliability of the consolidated data provided by the country’s oncological service. This opened up the opportunity to conduct in-depth epidemiological studies of the prevalence of MNP. This work pays special attention to the age patterns in the dynamics of MNP mortality indicators in the Russian population and takes into account the gender of the patients and the prevailing localization of neoplasms. The presented dynamics includes structural specifics of oncopathology for men and women of various age groups. The established patterns of reduced mortality in Russia’s population expressed in standardized indicators over a long period indicate that the anticancer policies pursued in the country have achieved real success.

Menopausal hormone therapy and heart disease prevention: desired or valid?

Cardiovascular diseases are the main cause of death for women in older age groups. For many decades, specialists have tried to prevent their development by the use of estrogen. The review of the literature presents current data on the effect of menopausal hormone therapy (MHT) on the risk of cardiovascular complications. The results of the main randomized clinical and observational studies in this area, conducted over several decades, are discussed. We described the concept of “window of opportunities”, in accordance with which an improvement in cardiovascular prognosis can be expected only at the onset of MHT in women under the age of 60 years in early postmenopause (menopause duration <10 years). There are experimental and clinical data explaining the different effects of estrogen on the cardiovascular prognosis in women of various age groups and different duration of postmenopause. The recommendations given in the review on the use of MHT are based on modern international guidelines.

Physiological indices of biological age in pregnant women of various age groups

The aims: to study the physiological indices, which characterize the biological age (BA) of the woman, in the process of physiological pregnancy and conduct a correlation analysis between these indices and the stage of pregnancy in different age groups. Materials and methods. Total of 122 pregnant women aged 20-34 years with different gestational age were selected for the study; all participants underwent a comprehensive functional examination. From the obtained results, the BA values were calculated using the in-depth «Kiev» scale as well as our own modification. Results. Upon an increase in the gestational age, there were changes in the BA-related indices in women of various age groups; these changes pertained to the vascular wall stiffness, respiratory functions, static balancing and the lens accommodation ability. Conclusion. The absence of changes in the BA, as calculated according to our modified test, during physiological pregnancy, suggests its applicability to women of young reproductive age. This calculation approach can be recommended for further studies in obstetrics and gynecology.

Особливості перебігу пологів у жінок різного віку

The objective: to study features of current of labors at women of various age groups. Materials and methods. Us were allocated the following age subgroups: 8–25, 26–28, 29–30, 31–35, 36–40, more than 40 years, among 715 women from whom 281 I was primapara, and 434 – multipara. Сliniсфд-laboratory and tool examination was conducted. Results. Results of the conducted researches testify that the current of labors at women of various age has the specific features which depend on age, the genesial anamnesis and existence of accompanying genital pathology. Frequency of an abdominal delivery increases depending on age and existence of disturbances of genesial function. Level of premature births also increases with augmentation of age of pregnant women. Frequency of late pregnancy and overdue labors tends to depression with age augmentation that the attention to maintaining women of the senior age group and active tactics of maintaining speaks larger. Сonclusion. The received results needs to be considered when developing tactics of maintaining labors at women of various age and parity. Key words: labors, complications, various age.

Ambient air quality and subjective stress level using Community Health Survey data in Korea.

OBJECTIVESAir pollution causes various disease in exposed populations, and can lead to premorbid health effects manifested as both physical and psychological functional impairment. The present study investigated the subjective stress level in daily life in relation to the level of air pollution.METHODSData from the Community Health Survey (2013), comprising 99,162 men, and 121,273 women residing in 253 healthcare administrative districts, were combined with air pollutant concentration modelling data from the Korean Air Quality Forecasting System, and were stratified by subjective stress levels into five strata for multiple logistic regression. Levels of exposure were divided into five quintiles according to the annual concentration of nitrogen dioxide (NO2), and were analyzed using a single-pollutant model using NO2 concentration only, and a multi-pollutant model adjusted for the concentration of particulate matter <10 μm in diameter.RESULTSAnalysis of men and women in various age groups showed the highest odds ratio (OR) for subjective stress level at the highest NO2 concentration quintile in men and women aged 30–64 years (men: 2.91; 95% confidence interval [CI], 2.12 to 4.01; women: 1.82; 95% CI, 1.32 to 2.51). As the NO2 concentration quintile increased, the OR increased. Men showed higher ORs than women in all strata.CONCLUSIONSIn the present study, annual NO2 concentrations were found to be associated with subjective stress levels. This association was especially clear among socioeconomically active men and women aged 30-64 years.

Invited Product Profile Alere RALS Connectivity for Point-of-Care Testing

Although many qualitative point-of-care tests are commercially available for detection of pregnancy including urine and serum human chorionic gonadotropin (hCG) tests, these products are often associated with higher risk of false-negative results and are not easy to use. The ADEXUSDx hCG Test uses only 1 drop (35–40 μL) of whole blood sample for the detection of hCG, making it suitable for capillary blood testing. Comparison with Access Total βhCG (5th IS) assay using 392 finger stick samples from women of child-bearing age demonstrated an overall agreement of 98.1%. Performance of the ADEXUSDx hCG Test was prospectively evaluated in 40 pregnant and 40 nonpregnant women aged 18 to 44 years. The hCG test generated 100% sensitivity and 100% specificity. Study of additional 318 nonpregnant women in various age groups demonstrated 99.7% specificity. The ADEXUSDx hCG Test is a rapid test (10 minutes) with demonstrated ease of use and clinical performance, making it a useful point-of-care test as well as over-the-counter test.

Arterial Flow, Pulse Pressure and Pulse Wave Velocity in Men and Women at Various Ages.

The increase in pulse pressure (PP) that occurs with advancing age is predominantly due to reduced arterial distensibility leading to decreased aortic compliance, particularly in the elderly, in whom high blood pressure mainly manifests as isolated systolic hypertension. Since age-related changes in stroke volume are minimal compared with changes in PP, PP is often considered a surrogate measure of arterial stiffness. However, since PP is determined by both cardiac and arterial function, a more precise and reliable means of assessment of arterial stiffness is arterial pulse wave velocity (PWV), a parameter that is only dependent on arterial properties. Arterial stiffness as measured by PWV has been found to be a powerful pressure-related indicator for cardiovascular morbidity and mortality. We analyzed PP and PWV in men and women of various age groups in healthy volunteers as well as cardiac patients with different types of diseases. The findings identified several striking sex-specific differences which demand consideration in guidelines for diagnostic procedures, for epidemiological analysis, and in evaluation of therapeutic interventions.

Linking Reminders and Physician Breast Cancer Screening Recommendations: Results From a National Survey.

Physician reminders have successfully increased rates of mammography. However, considering recent changes to breast cancer screening guidelines that disagree on the optimal age to start and stop mammography screening, we sought to examine the extent to which reminders have been deployed for breast cancer screening targeting younger and older patients. A mailed survey was sent to a national sample of 2,000 primary care physicians between May and September 2016. Physicians were asked whether they received reminders to screen women in various age groups (40 to 44, 45 to 49, and ≥ 75 years), the organizational screening guidelines they trusted most, and whether they recommended routine breast cancer screening to average-risk women in the different age groups. Using regression models, we assessed the association between reminders and physician screening recommendations, controlling for physician and practice characteristics, and evaluated whether the association varied by the guidelines they trusted. A total of 871 physicians responded (adjusted response rate, 52.3%). Overall, 28.9% of physicians reported receiving reminders for patient ages 40 to 44 years, 32.5% for patient ages 45 to 49 years, and 16.5% for patient ages ≥ 75 years. Receiving reminders significantly increased the likelihood of physicians recommending mammography screening. In adjusted analyses, 84% (95% CI, 77% to 90%) of physicians who received reminders recommended screening for women ages ≥ 75 versus 65% (95% CI, 62% to 69%) of those who did not receive reminders. The associations between reminders and screening recommendations remained consistent regardless of which guidelines physicians reported trusting. Reminders were significantly associated with increases in physician screening recommendations for mammography, underscoring the need for careful implementation in scenarios where guidelines are discordant.

FEATURES OF CURRENT ACUTE CORONARY OF A SYNDROME/ACUTE MYOCARDIAL INFARCTION AT THE WOMEN IN ONE OF AREAS OF CITY OF TASHKENT (fragment of the register ACS/AMI)

Objective. The questions of female health last years get the increasing urgency cardiovascular disease occupy a leading place in structure смертности from the women in the different countries. Often risk of development cardiovascular disease at the women is underestimated, mainly because their first displays at the women develop approximately for 10 years later, than at the men. However given Fremingem of research testify to that that, despite of smaller frequency ишемической of coronary heart disease (CHD) at the women, mortality at them is higher, than at the men.Aim. To study features of development and current acute coronary syndrome and acute myocardial infarction at the women in various age groups in one of areas of. Tashkents (on the data of the register). Methods. 219 women, which average age = 59,48±7,51 years were switched on in research. The data received in past research" The Register acute coronary syndrome and a acute myocardial infarction in one of areas of were analyzed. Tashkents " for 2009 -2010 years. The preventive, statistical, mathematical methods of research were used.Results. The results of our research have shown, that asymptomatic the debut of disease was marked in 1 (0,7%) case the isolated pain in thoracal to a crate was fixed at 3 (2,1%) пациенток, the combination of this symptom with dyspnea met at 7 (4,9%), weakness - at 20 (13,9%), and with cold then - at 1 (0,7%) patient. The presence dyspnea, in a combination to weakness was registered at 10 (6,9%), and dyspnea with cold then - at 2 (1,4%) patients. The weakness as the isolated symptom met at 2 (1,4%) patients. A combination of four symptoms: pain in a breast, dyspnea, weakness and cold sweat were registered at 16 (11,1%) patients. Pain, dyspnea, syncope and cold sweat marked 1 (0,7%) woman.Conclusion.The results of our research have shown, that in process of increase of age at the women the growth acute coronary of pathologies is observed. Most often ACS/AMI develops at the women in age group 60-64 and 65-69 years. The analysis on risk factor (RF) as a whole on group has shown, that most widespread from them were AH and superfluous weight of a body. At the young women conducting risk factors have appeared smoking and obesity. With age the role such a RF, as AH, diabetes mellitus (DM) and hypercholesterolemia is increased. The low adherence to treatment and low level of knowledge is shown concerning acute coronary of a pathology.

Unprovoked venous thromboembolism and subsequent cancer risk: a population‐based cohort study

ESSENTIALS: A relationship between unprovoked venous thromboembolism (VTE) and cancer risk was investigated. We collected 27,751 VTE patients and compared them with 110,409 frequency-matched people without VTE. This cohort study showed significantly higher risks of overall and site-specific cancers in the VTE group. There is an increased risk in the first 6 months after VTE, and VTE can be an indicator of occult cancer. We investigated the relationship between unprovoked venous thromboembolism (VTE) and subsequent cancer risk in Taiwan, focusing on both short-term and long-term cancer development. For the case group, we obtained data on 27,751 patients diagnosed with unprovoked VTE between 1 January 1998, and 31 December 2008. For the comparison group, four people without unprovoked VTE were frequency-matched with each unprovoked VTE patient according to age, sex, and index year. Cox proportional hazards regression models were employed to determine the effects of unprovoked VTE on cancer risk. Overall cancer risk was significantly higher in the unprovoked VTE group than in the comparison group (adjusted hazard ratio = 2.26, 95% confidence interval = 2.16-2.37). The increased risk was observed in both men and women in various age groups. The patients in the unprovoked VTE group showed a significantly increased risk of cancer at all site-specific cancer sites. Analyses stratified according to follow-up duration revealed that significant differences were more evident between the two groups over a follow-up duration of < 0.5 years than over a follow-up duration of ≥ 3 years. Furthermore, the 1-year mortality risk of cancer patients with unprovoked VTE was significantly higher than that for cancer patients in the non-VTE group. The results of this study show that unprovoked VTE is associated with a consistently high risk of subsequent cancer diagnosis. This is particularly true in the first 6 months after VTE. It suggests that unprovoked VTE can be an indicator of occult malignancy.

Occurrence of urinary tract infection in adolescent and adult women of shanty town in Dhaka City, Bangladesh.

Urinary tract infection (UTI) is commonly experienced by women of various age groups especially elderly ones. We planned to find out the prevalent microbial strains causing UTI in slum inhabitant adolescent and adult women in Dhaka City, Bangladesh. Urine sample was collected from 462 UTI suspected female subjects. Pathogenic bacteria were identified using standard microbiological tests, and antimicrobial sensitivity profiles of the pathogens were determined. Bacteriuria was present in 9% of the subjects. A higher incidence (16.8%) of UTI was noted among adult women aged above 19 years. Escherichia coli (69%), Streptococcus spp. (15%) and Pseudomonas aeruginosa (7%) were more frequently isolated from the urine samples compared to Enterococcus faecalis (3%), Staphylococcus aureus (2%), Klebsiella pneumoniae (2%) and Hafnia alvei (2%). The E. coli isolates showed complete resistance to commonly used drugs, and 58% of these isolates were multidrug resistant (MDR). Minimum Inhibitory Concentration (MIC) values for ciprofloxacin ranged between 64µg/ml and 512µg/ml, and the Minimum Bactericidal Concentration (MBC) values against the isolates were 128µg/ml or above. Isolated strains of E. coli exhibited equal extent of ciprofloxacin resistance irrespective of the presence or absence of plasmid in them. The extent of drug resistance among the uropathogens if ignored may render them uncontrollable. This study suggests regular monitoring of drug resistance phenotype of the UTI pathogens to reduce the morbidity of female UTI patients and offer better treatment strategy in the healthcare sectors of Bangladesh.

A Survey of Utilization and Effectiveness of Insecticide – Treated Bednets (Itns) As Intervention Strategy in Malaria Transmission among Pregnant Women in a Rural Community in Ebonyi State, South Eastern Nigeria

One hundred and twenty eight (128) pregnant women of various age groups and gravidities who were at their different trimesters were interviewed to match their use of ITNs with their episodes of malaria. Structured closed ended interviewer administered questionnaire was used to collect data. The age range of the women was between 15 and 47 years. All of them owned insecticide - treated bed nets while only few of the owners utilized them. All the women attended antenatal care (ANC) at the government health care centres. Forty six (35.94%), 42(32.81%), and 40(31.25%) were primigravidae, secundigravidae, and multigravidae respectively. Thirty eight (29.70%), 47(36.72%), and 43(33.60%) were at their 1 st , 2 nd and 3 rd trimesters respectively. Thirty seven (28.91%) of the entire sampled population utilized their bed nets, with those within the age group of 15 - 19 years making more use of their bed nets while those at 40 years and above made least use of theirs. Women at their 2 nd trimesters of pregnancy utilized their bed nets most. Women within the age bracket of 15 -19 years and 20 -24 years utilized their bed nets better and experienced an average frequency of malaria episodes of 1 (once) while those who were 40 years and above made the least use of the bed nets and experienced the highest average frequency of malaria episodes of 5. An average frequency of malaria episode of 6 was observed among the primigravidae, while the secundigravidae who highly utilized their bed nets had an average episode of 4. Women in their 2 nd trimesters utilized bed nets most and had the least average malaria episode of 3. Those in their 1 st and 3 rd trimesters each had an average malaria episode of 6.

The attitudes of Australian gynaecologists to HPV vaccination: An ASCCP survey

With human papilloma virus (HPV) vaccines now approved for women up to 45 years of age, gynaecologists in Australia will be approached increasingly for advice on whether to have the HPV vaccine. We seek to establish the attitudes of gynaecologists to HPV vaccination when advising women in various age groups. Fellows, members and trainees of Royal Australian and New Zealand College of Obstetricians and Gynaecologists were approached in early 2009 to complete an Australian Society for Colposcopy and Cervical Pathology survey, which they could return by post or internet on-line. There were 836 (49.0%) responses, with 35.6% of responders using 'Tuna' on-line. 836 RANZCOG fellows, members and trainees responded to the survey. The gender of responders are 261 (43%) females and 470 (56%) males. Of the responders, 391 (46.8%) usually initiated discussion regarding the role of HPV vaccination with their patients. More than 93% encourage when recommending the HPV vaccines for female responders aged 12-26 years. This proportion decreased to 66% for women aged 27-45 years, with 15% strongly encouraging vaccination for this age group. The attitudes to HPV vaccination for the different age groups of females were similar for trainees, fellows and members, as well as for gender and age groups of the responders. However, those with lower level of knowledge are less likely to encourage HPV vaccination in all vaccination age groups and the association is statistically significant after adjusting for role, gender and age. The results show a strong support from gynaecologists in Australia for HPV vaccination.

Teaching and Learning Guide for ‘Beauty Work: Individual and Institutional Rewards, the Reproduction of Gender, and Questions of Agency’

Teaching and Learning Guide for ‘Beauty Work: Individual and Institutional Rewards, the Reproduction of Gender, and Questions of Agency’

Blood Rheology and Risk of Thromboembolism in Adult and Climacteric Women

Increased age is associated with an increased thrombosing tendency, especially deep vein thrombosis and pulmonary embolism. We investigated blood flow in women of various age groups and found that blood flow decreases with advancing age. Because decreased blood flow can lead to platelet and leukocyte activation, it could be related to the pathogenesis of venous thromboembolism with age.

Extraction, Purification, and Development of an Enzyme‐Linked Immunosorbent Assay for Osteocalcin

The present study describes the isolation and purification of osteocalcin (OC) from bovine bones and the development of an enzyme‐linked immunosorbent assay (ELISA) for OC as a marker of bone formation, for assessing bone health. Bone proteins were extracted from about 90 g of bovine bone powder using 20% formic acid. The protein extract was fractionated by gel permeation chromatography on Sephadex G‐50 column followed by fast protein liquid chromatography (FPLC) on a MONO‐Q column. The immunoreactive active fraction was then purified by chromatofocusing, using FPLC on a MONO P column and a single homogeneous band of molecular size of about 5.8 kDa, as judged by Tricine SDS‐PAGE following silver staining of the gel, was obtained. It reacted specifically with its antibodies in an ELISA. About 678 µg of purified OC was yielded from about 90 g of bovine bones. The purified OC was subsequently used for the raising antisera, which was used in the development of an indirect ELISA. The developed ELISA has a sensitivity of 2.5–4.0 ng/mL and was used in estimating levels of OC in women of various age groups.

Neurocognitive function in women affected by the Bhopal gas disaster

Background:Methyl isocynate (MIC) is a reactive, toxic, volatile and inflammable gas. Exposure to MIC causes neurotoxicity and somatic abnormalities in human beings.Aim:We compared neurocognitive function in MIC-exposed women and a control group, as well as cognitive function in the MIC group and examined them with reference to age.Methods:The study sample comprised 30 women and a control group of 30 women. Both the groups were subjected to a detailed neuropsychiatric examination along with assessment of neurocognitive function using the PGI-Battery of Brain Dysfunction (PGI-BBD).Results:Mean scores of immediate recall, visual retention, difference in performance quotient/verbal quotient, Nahar–Bensen and Bender–Gestalt test were significantly affected in MIC-exposed women. However, among MIC-exposed women, neurocognitive functions were similarly affected in women in various age groups.Conclusion:Women in the MIC-exposed group had significant neurocognitive dysfunction in some specific areas as compared to women in the control group. The mean score of dysfunction rating of the PGI-BBD showed significant differences in neurocognitive functions between MIC-exposed and non-exposed women.