Bioconvection has recently become a point of contention in several biotechnological fields that rely on fluids and their physical properties. Bioconvection tends to happen when mixed nanofluids are subjected to elevated and mass transmission. I'm fascinated by the widespread use of bioconvective nanofluids in the construction of microbial fuel cells, microbial oil extraction mechanisms, processing plants, and other applications. Current research looks at the heat and mass transport properties of cross-nanofluid. Effects of stratification for double diffusion are also considered. Variable thickness sheets are increasingly being used in civil engineering, mechanical, aeronautical, and maritime processes and constructions. Flow and heat transfer across stretching surfaces is used in many technical processes, including polymer extrusion, plastic film stretching, food, and paper processing, fiberglass manufacturing, wire drawing, and continuous casting. Primary goal of the ongoing research is to learn about the properties of activation energy, nonlinear thermal radiation, heat sink source, and motile microorganisms of three-dimensional cross nanofluid flow. The bvp4c structure is used to numerically encode the boundary value problem in the MATLAB mathematical code. To retrieve numerical and graphical reports on velocity, thermal, and energy profiles versus the values of the most important physical parameters, graphs and tables were used.