To improve the wear resistance of Titanium alloy, TiAl intermetallic claddings were fabricated on TC4 substrate using laser melting deposition technology. Optical microscope, scan electron microscope (SEM), energy dispersive spectrometer (EDS) and X-ray diffraction meter were applied to investigate the deposited TiAl layer and their interface with substrate. Using hardness tester and M-2000 wear testing machine, hardness, frictional coefficient and wear resistance of the TiAl layers and TC4 alloy were tested. It was indicated that the deposited TiAl layers were well integrated with TC4 substrate, γ-TiAl and Ti3Al dual phase microstructure was formed in the deposited layer. With higher hardness and lower friction coefficient, the deposited TiAl layer improved the wear resistance obviously comparing to TC4 titanium alloy substrate.