The materials on the history of the development of documents and the experience of the veterinary service to improve the state veterinary inspection over the safety of products of animal origin in the new economic conditions are presented. Many years of experience in veterinary support of cattle breeding revealed a number of significant shortcomings in the organization of veterinary business: lack of adequate conditions for the work of veterinary specialists of the state veterinary network and farms; imperfect remuneration of labor, veterinary specialists' salary does not depend on the level of their professional training, complexity and quality of work; lack of material and technical support; weak legal protection; imperfect legislation on veterinary services, diversion of specialists to perform unrelated to their profession labor activities, and lack of normal social and living conditions. All this leads to the loss of prestige of the veterinary profession, the outflow of veterinary professionals to other areas of production. Hence the low staffing of veterinary institutions and farms. Scientists and veterinary specialists of Novosibirsk have done work on the search for such forms of organization of veterinary services for cattle breeding. The system of organization of self-supporting associations which can effectively operate in all categories of farms is proposed. The necessary guiding documents for the organization and their subsequent practice have been developed. The experience of selfsupporting veterinary associations in a number of districts showed that labor productivity increased by 1.5-2 times, the workload per veterinary specialist increased and the salary increased accordingly. The work carried out has proved the need to improve the activities of the state veterinary service in the context of economic reforms.