A 3-D, steady, conjugate numerical model is used to study the effect of waviness on laminar fluid flow and heat transfer characteristics associated with microsized wavy channels. The numerical model has been validated against available experimental data. It is observed that transition Re and average Nu are functions of waviness of the channel; however, friction factor remained constant at higher waviness. The augmentation of Nu with waviness is found to be resulting from increased levels of recirculation and secondary flows. Peak vorticity levels showed an increase of six times when relative waviness increased from 0.03 to 0.3 and is about 2.5 times when Re increased from 100 to 200. The effect of chaotic advection is not observed even for higher waviness channels at Re = 100.