A fluorogenic and electrochemical chemosensor BHMMP has been synthesized for aqueous phase ppb level detection of Zn2+ and Cd2+. The chemosensor exhibited distinct CHEF-based turn-on fluorometric transformation upon the addition of Zn2+ and Cd2+ respectively. Distinct fluorogenic response of BHMMP in presence of urinary excreted Zn2+ and human salivary Cd2+ indorsed the chemosensor towards a prefatory diagnostic tool for urinary Neoplastic disease and salivary Amyotrophic Lateral Sclerosis (ALS). The bio-compatibility of BHMMP was validated through in-vitro detection of Zn2+ and Cd2+ distinctively in the MCF-7 cancer cell line. BHMMP exhibited a paper-strip-based distinct fluorogenic response upon the addition of a trace amount of Zn2+ and Cd2+. A lumino-readable ‘information storage system’ was developed which strengthened the on-field applicability of BHMMP. The sensing response was rejuvenated by the addition of EDTA2−, which showcased a design of a four-input-three-output ‘fishtail’ mimicking logic gate circuitry. Sensing phenomena were corroborated through, Photoluminescence, ESI-MS, cyclic voltammetry, 1H NMR, FTIR, and DLS along with an in-silico approach. Additionally, synthesized ‘H’ type organic nano aggregate out of BHMMP (BHMMP-ONA) exhibited F− scavenging efficiency in a wide range of contaminated water samples. Therefore, the multichannel applications of this probe are expected to find imminent effectiveness in the realm of point-of-care testing.