The assessment of the impact of hostilities on the environment remains an important issue for predicting changes resulting from military-technogenic activities and assessing the losses incurred by ecosystems in Ukraine. This article proposes an integrated approach for predicting the possible level of hostilities’ impact by utilizing aggregated environmental information on ecosystem composition, indicators of military-technogenic load, organization of trophic networks in relevant biogeographic zones, and biodiversity composition. The concept of environmental safety of hostilities is introduced as a projection into the military technosphere of the ecosystem sustainability concept, where the target function is the conservation of the natural biota of operational zones and areas of hostilities. The article presents a block diagram of the procedure for assessing the state of ecosystems in war zones and proposes a classification of levels of military-technogenic disturbance of natural ecosystems based on the state of edifier sinusia.