ABSTRACT Transition to adulthood can be challenging for individuals with intellectual and developmental disabilities (IDD), with and without concurrent mental health conditions. Research shows that young adults with disabilities face a variety of barriers and are more likely to be unemployed than those without a disability. Occupational therapy practitioners (OTPs) can play an integral role in supporting young adults as they transition out of school and into supported or competitive employment. The Occupational Therapy Vocational Profile (OTVP) was developed to support young adults with IDD, with or without concurrent mental health conditions, as they leave school and transition to adulthood. The OTVP is a non-standardized, comprehensive evaluation tool that consists of three subtests based on the Person-Environment-Occupation (PEO) Model. It includes a summary of results that provides a description of an individual’s goals, interests, strengths, needs, and recommended vocational accommodations. This article discusses the development and pilot testing of the OTVP in a residential school setting. The OTVP may provide OT practitioners, educators, vocational staff, and employers with information to support young adults seeking supported or competitive employment after high school.