Dust pollution control is the basic guarantee of mine safety production, which has been widely concerned by scholars. Based on a total of 1786 publications collected by the Web of Science Core Collection (WOSCC) from 2001 to 2021, this paper analyzes the spatial-temporal distribution characteristics, hot topics, and frontier trends of the international mine dust field during the past 20years by using Citespace and VOSviewer knowledge graph technology. The research shows that the study of mine dust can be divided into three stages: initial period (2001 ~ 2008), stable transition period (2009 ~ 2016), and boom period (2017 ~ 2021). The journals and disciplines which belong to mine dust research mainly focus on environmental science and engineering technology. A stable core group of authors and institutions have been preliminarily formed in the dust research field. The main themes of the study contained the whole process of mine dust generation, transport, prevention, and control, as well as the consequences of disaster. At present, the hot research fields mainly focus on mine dust particle pollution, multi-stage dust prevention, and emission reduction technologies, and mine occupational protection, monitoring, and early warning. In the future, the research should focus on the mechanism of dust production and transportation, the theory of efficient prevention and control, the technology and equipment of precise prevention and control of dust, and the high-precision monitoring and early warning of dust concentration. Future research should be concerned with dust control in underground mines and deep concave open-pit mines with complicated and treacherous environments, and strengthen research institutions, interdisciplinary cooperation, and interaction so as to promote the integration and application of mine dust and automation, information, and intelligent technology.