Objective: This article analyzes how ASEAN countries utilize regional mechanisms in implementing humanitarian assistance and disaster management. Method: Using the qualitative method, this article shows that ASEAN regionalism in disaster management is quite effective. Secondary data is obtained through library research, utilizing various publications such as books, journals, documents, and the Internet. Results and conclusion: The research results show that ASEAN has made protecting society from natural disasters one of its goals since its formation. But the unequal capacities of ASEAN countries have driven different domestic levels of responses. ASEAN regional cooperation maximizes ASEAN’s capacity by unifying each country’s capabilities in ASEAN’s relations with the extra-regional powers. Even though it has the principle of non-intervention, the existence of the ASEAN Coordinating Centre on Humanitarian Assistance on Disaster Management (AHA Center) has removed the obstacles for parties who wish to send out aid to disaster areas in ASEAN member states. Originality/value: ASEAN has produced various mechanisms for handling victims of natural disasters. In its development, the efforts to protect against natural disasters have become very important because they have become an aspect of non-traditional security. Therefore, what ASEAN faces is not only the natural disaster itself but also how to save its citizens from non-traditional security threats.