<p style="text-align: justify;">Pressure vessels that are exposed to high stresses, due to unfavorable working conditions during exploitation, must be properly designed, taking into account all calculation factors, in order to be safe during their expected lifetime. Checking the condition of the vessel, or analyzing the load of the vessel in working and test conditions, is mandatory. In recent times, numerical analysis represents one of the most important methods of analyzing the stress states of all structural elements, including pressure vessels. It enables precise determination of the location of the greatest stresses and deformations. In this paper, a stress analysis of a vertical cylindrical pressure vessel type VS 110 with a spiral for heating and cooling, with a volume of 3750 liters and a working pressure of 3 bars, which is used for the preparation of medicines in the pharmaceutical<br />industry, was performed. The calculation of the vessel was made according to the EN 13445 standard and regulations on pressure vessels. Then a numerical stress analysis was performed in the Autodesk Inventor 2023 software package. The results of the numerical analysis show that the highest stresses occur in the torispherical parts of the vessel end. Furthermore, the cylindrical nozzles on the shell as well as on the torispherical ends act as a reinforcement of the vessel because there is a stress reduction in their vicinity.</p>
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