Purpose: to analyze the thermal load of the server cluster of the high-performance computing laboratory, stabilize the temperature regime of the room throughout the year, taking into account seasonal changes in the ambient temperature. Methodology: performing experimental studies using modern devices and analyzing experimental data to assess the heat load of server clusters at various degrees of their workload with calculations. Results: a thermal analysis of the work of the server cluster of a high-performance computing laboratory was carried out at various degrees of server load with calculations. Temperature measurements were carried out for various zones and elements of server racks, temperature changes were established when the servers were loaded with calculations. In the modern CFD system, the air flows of the server cooling system and the temperature regime of the server cluster and the server room are simulated, taking into account the location of the equipment and information about the measurements of temperatures and air flow rates. As a result, temperature distributions were obtained for different server loads. A comparison of the supply and exhaust ventilation options was carried out; equipment was selected to ensure the effectiveness of temperature stabilization in the server room at the required level. ISSN 2308-5312 Наукові праці ДонНТУ. Серія: «Машинобудування і машинознавство». No1(14)’2020 20 Scientific novelty: the assessment of heat dissipation during the operation of the server cluster was carried out, the temperature regime of the operation of the server room objects was simulated and the temperature distributions were obtained for different server loads. Practical significance: the design of the room with the location of equipment for supply and exhaust ventilation is proposed; the main parameters of equipment for effective ventilation to reduce the heat load of server racks are determined, recommendations for the use of heat laboratories of high-performance computing for partial heating of the educational building of the state higher educational institution