The pre-season plays a crucial role in the preparation of professional football players, as it allows for an extensive focus on training sessions compared to the more congested schedules during the in-season period, especially in professional football leagues. This study aimed to describe the workload during a 6-week pre-season in Belgian professional football players and to analyse and compare the workloads for players in each microcycle according to several variables of external workload (e.g., distance covered at some velocities). Seventeen male Belgian professional football players competing in the second division of the Belgian league system participated in the study. Throughout the 6 weeks, the players were closely monitored during both training sessions and friendly matches using Global Positioning System (GPS) devices. Several parameters, including total distance covered and distance at different velocities, were recorded. Accelerating and decelerating distances, as well as the number of sprints, were also captured. Statistical analysis was based on a repeated measures ANOVA, percentage dynamics, and effect size calculations. The results obtained showed a progressive increase in the distance travelled at different intensities from week 1 (i.e., lower values) to week 3 (i.e., higher values), with reductions in these values in week 6, prior to the start of the official competition. Similarly, the peak of accelerations and decelerations were observed in week 2 and week 3, with decrements at the end of the pre-season period. This comprehensive investigation attempts to shed light on the effects and dynamic changes in external workload during the crucial pre-season, contributing valuable insights for coaches and practitioners in football conditioning and training programs, especially concerning optimal preparation for the beginning of the league’s season.