The Variational Monte Carlo (VMC) method is employed to determine characteristics of symmetric and asymmetric nuclearmatter. The realistic Urbana v14 nucleon-nucleon interaction potential of Lagaris and Pandharipande was used in the VMC calculations with addition of a phenomenological density-dependent term to simulate many-body interactions. A new Skyrme parameter set SKaan-U14 is found to consistently reproduce the characteristics of the nuclear matter obtained from VMC calculations. The properties of symmetric and asymmetric nuclear matter are calculated by the new Skyrme parameter set. The results obtained by using the new Skyrme parameter set are compared with results obtained by different Skyrme parameter sets in the literature.