Value Of Test Research Articles

Assessment of reproducibility and influence of different dental specialties on functional implant prosthodontic score: A prospective clinical study analyzing single-unit implant crowns.

Implant therapy in partially edentulous patients has become the most adapted and predictable treatment modality. The success rate of implants has been measured in terms of esthetic, biological, and technical factors such as radiographic bone loss, prosthetic complications, and stability. Despite the existence of several indices for the esthetic assessment of implant crowns, a need for functional evaluation of the implant crown with an objective and reproducible score has arisen. The study aims to validate the reproducibility of the functional implant prosthodontic score (FIPS) and the influence exerted by different dental specialties while evaluating posterior single-unit implant crowns. This was a prospective clinical study. Fifteen patients with cement-retained single-implant crowns in the posterior region of the jaws were included. Eight examiners, two prosthodontists, two periodontists, two oral surgeons, and two orthodontists evaluated 15 photographs of single-unit implant crowns during the 1-year follow-up examination. The examiners assessed the photographs for FIPS, which includes five parameters for objectively evaluating the single-unit implant crowns. Assessments were performed twice at a gap of 4 weeks. Pearson's correlation with a 95% confidence interval was calculated for the intra-examiner and the Kruskal-Wallis test for inter-examiner reproducibility. The mean total FIPS scores for all included examiners were 7.133 for time T1 and 7.074 for time T2, showing a strong Pearson correlation coefficient for intra-examiner reproducibility. No significant difference was analyzed among different specialties with statistically significant values of the Kruskal-Wallis test. Intra- and inter-examiner analysis showed very consistent results during the reproducibility assessment of FIPS. The results validated the use of FIPS as a long-term predictive functional evaluation tool for the single-implant crowns in posterior sites irrespective of the effect of different dental specialties. It could be used for risk estimation and prognosis for long-term survival and performance of implant crowns.

Evaluation of hepatic and renal functional changes in patients undergoing laparoscopic cholecystectomy

Background: In this era of laparoscopic surgery, with the use of carbon dioxide insufflation in creating pneumoperitoneum for ease of trocar insertion and visualization of anatomy, it comes certain systemic changes in the patient due to the compression effect of the gas as well as resorption of it through peritoneum. Aims and Objectives: The aim of the study was to assess baseline standards of hepatic and renal functional status in pre-operative patients in comparison with post-operative patients undergoing laparoscopic cholecystectomy (LC). Materials and Methods: Cases were chosen among the persons who presented with chronic calculus cholecystitis to the surgical out-patient department of Ramakrishna Mission Seva Pratishthan, Vivekananda Institute of Medical Sciences, Kolkata. Pre-operative liver function tests (LFT) and renal function tests (RFT) values were recorded. Again, LFT and RFT values were evaluated on post-operative day 1 (POD1) and POD12. Results: Serum conjugated and unconjugated bilirubin, aspartate amino transaminase, alanine amino transaminase, urea, estimated glomerular filtration rate values increases immediate postoperatively on POD1 but returns to normal pre-operative levels on POD 12. Serum alkaline phosphatase, albumin, and creatinine values decrease on POD1 and return to normal pre-operative values in POD 12. Conclusion: Hepatic and renal function changes in the immediate post-operative period of 24 h following LC. This change is transient and returns to normal levels within POD 12.

Psychometric properties of the Greek Inventory of Personality Organization – Brief (IPO-Brief-GR) in a community sample of emerging adults

Several studies have evaluated different versions of the Inventory of Personality Organization (IPO) around the world and some shortened versions of the instrument have also been constructed. The aim of this study was to develop the first brief Greek-language version of the IPO (IPO-Brief-GR) to be used for clinical screening and research purposes regarding personality pathology defined according to Kernberg's object relations model of personality organization. Data were collected from a community sample of 543 Greek emerging adults aged 18–29 years (M = 21.45, SD = 2.51) with the 83-item IPO, from which a 30-item version was constructed, based on confirmatory factor analysis of the full measure. The psychometric properties of the IPO-Brief-GR were then examined. Confirmatory factor analyses indicated that a four-factor structure best fitted the data, that is, primitive defenses/identity diffusion, reality testing, aggression, and moral values. Criterion validity and internal consistency reliability were also supported. Measurement invariance across gender using an exact protocol approach (i.e., configural, metric, scalar) was found allowing latent mean comparisons. These preliminary findings support the reliability and validity of the IPO-Brief-GR for the assessment of borderline personality organization and indicate the need for further research into the psychometric properties and clinical utility of this measure.

Clustering method for criminal crime acts using K-means and principal component analysis

Criminality is an act of violating the values and norms of society that causes a lot of harm. Much of the criminal data is often just a collection of data that has no information. Analysis of crime data is key in efforts to reduce crime rates that provide an overview of the incidence of crime, patterns, levels of vulnerability, and the level of security of an area. This research proposes data analysis that provides an understanding of crime using data mining techniques, especially the K-means cluster method, both traditional and with principal component analysis (PCA) dimension reduction. Before the PCA process, the values are transformed first with Z score normalization. From the processing through the davies bouldin index (DBI) performance test with 3 clusters, it is concluded that traditional K-means produces a DBI Index value of 0.019 and K-means PCA of 0.299. Meanwhile, to see the optimal cluster, several iterations were performed and resulted in the most optimal DBI index of 4 clusters in K-means of 0.014 and K-means PCA of 0.172. From the performance test value, it means that in the context of clustering the traditional criminal K-means data is declared more optimal than K-means PCA.

Component method and numerical investigation on the initial rotational stiffness of fillet welded rectangular hollow sections (RHS) T-joints

The initial rotational stiffness of the joint has a significant effect on the distribution of internal forces between the members. However, the original component method for calculating the initial rotational stiffness of fillet welded RHS T-joints does not consider the effect of fillet welds, which often results in an underestimation of the initial rotational stiffness. Therefore, in this paper, a modified component method based on the original component method is proposed to calculate the initial rotational stiffness of the joint, which focuses on the effect of the fillet weld size. The modified component method is compared with the original component method and tests to verify its reliability. Subsequently, parametric analyses were performed using the validated numerical model. The results show that (1) the mean value of the ratio of the initial stiffness of the joint calculated by the modified component method to the test value is 1.03, and the COV is 0.014. For the original component method, the mean value of the ratio is 0.72, and the COV is 0.018. (2) The initial rotational stiffness of the joint increases with the increase of the fillet weld throat thickness, chord thickness, and brace-to-chord width ratio (β), and the modified component method and the numerical simulation results are in good agreement. In conclusion, this paper's modified component method is more accurate and has better prediction performance than the original component method.

Differentiating viral and bacterial infections: A machine learning model based on routine blood test values

The growing threat of antibiotic resistance necessitates accurate differentiation between bacterial and viral infections for proper antibiotic administration. In this study, a Virus vs. Bacteria machine learning model was developed to distinguish between these infection types using 16 routine blood test results, C-reactive protein concentration (CRP), biological sex, and age. With a dataset of 44,120 cases from a single medical center, the model achieved an accuracy of 82.2 %, a sensitivity of 79.7 %, a specificity of 84.5 %, a Brier score of 0.129, and an area under the ROC curve (AUC) of 0.905, outperforming a CRP-based decision rule. Notably, the machine learning model enhanced accuracy within the CRP range of 10–40 mg/L, a range where CRP alone is less informative. These results highlight the advantage of integrating multiple blood parameters in diagnostics. The "Virus vs. Bacteria" model paves the way for advanced diagnostic tools, leveraging machine learning to optimize infection management.

The Influence of State Identity on Student Aggressivity

Aggressiveness is behavior that hurts, injures, harms and is detrimental both physically and psychologically. State identity is organizing, encouraging, believing in oneself to make self-decisions. This research is limited, the purpose of this study is to determine the effect of state identity on aggressiveness in semester 4 students at Palembang city, South Sumatra, Indonesia. The total number of research respondents was 45 people. Data collection was carried out through a questionnaire with a quantitative research type. This research was developed with the development of Taufik's (2011) scale concerning the effect of identity status on aggressiveness. The results of the research analysis showed that the significance hypothesis test value was 0.43, the normality test was 0.48 and the linearity test was 0.14. Referring to the deviation from sign value of 0.05, it can be concluded that there is a significant relationship between state identity and the aggressiveness of 4th semester students.

Pengaruh Pembiasaan Berbusana Muslimah terhadap Peningkatam Akhlak Mulia Peserta Didik Kelas XI di MAN 2 Bogor

The background to the problem of this research is that students do not meet the criteria for Muslim women's clothing, such as covering the entire body/genitals which must be covered. This is proven by the fact that there are still students whose clothing does not comply with school regulations. Where students still wear tight clothes and wear very narrow skirts, they assume that Muslim dress is only a school rule. Therefore, to solve the problem above, one solution is to use the habit of wearing Muslim clothing. The aim of the research was to determine the habit of wearing Muslim women's clothing in class The research method uses field research with a quantitative approach and data collection uses observation and questionnaires. The results of the research show that the simple linear regression test value is known to be Tcount = 4.178 > Ttable 1.686, so it can be concluded that the variable habituation to Muslim women's clothing (X) influences the variable noble morals (Y).

Semi-quantitative metalloproteinase-8 rapid test for the prediction of adverse pregnancy outcomes in patients with preterm premature rupture of membranes

ObjectiveWe aimed to determine whether the semi-quantitative metalloproteinase-8 (MMP-8) bedside test is a worthwhile indicator in reflecting the severity of of intra-amniotic inflammation (IAI) and in predicting adverse pregnancy outcomes. Study DesignThis retrospective cohort study comprised 76 singleton-pregnant women admitted to the Seoul National University Bundang Hospital with a diagnosis of preterm premature rupture of membranes (preterm PROM) between 20 weeks 0 days and 33 weeks 6 days of gestation who underwent trans-abdominal amniocentesis to confirm intra-amniotic infection by positive results for aerobic/anaerobic bacteria, fungi, and genital mycoplasma and evaluate lung maturity. The semi-quantitative MMP-8 rapid test kit employs a colourimetric assay to quantify MMP-8 levels in amniotic fluid (AF), expressing results from 0 to 100 percent. Participants were divided into three groups: group 1, including negative MMP-8 test with colour scale of 0 % (negative, n = 17); group 2, including positive MMP-8 test with colour scale < 51 % (weak positive, n = 21); and group 3, including positive MMP-8 test with colour scale of 51 %–100 % (strong positive, n = 38). ResultsApproximately 78 % (59/76) of the participants showed a positive MMP-8 test result; all culture-proven AF samples (33.3 % [25/75]) yielded positive MMP-8 test, categorizing these patients into either group 2 or group 3. A significant trend was observed where the rate of positive culture-proven samples increased with the progression from group 1 (negative) to group 3 (strong positive). Both white blood cell counts in AF and maternal serum C-reactive protein levels were found to escalate with the progression of test results from negative to strong positive. This progression was associated with an increased risk of spontaneous preterm birth within 48 h, 7 days, and 14 days from amniocentesis and within 34 weeks of gestation. ConclusionThe more the test results progress from negative to strong positive, the shorter the interval from amniocentesis to delivery becomes, and the higher the risk of intra-amniotic infection, spontaneous preterm delivery, and other perinatal complications. This relationship highlights the critical value of the semi-quantitative MMP-8 rapid test in predicting adverse pregnancy outcomes in patients with preterm PROM.

Effect of HIIT on Motor Performance in Female Handball Players

Abstract: The aim of this study was to investigate the effects of interval training at four different intensities in addition to handball training for 8 weeks on aerobic-anaerobic, speed and agility pa-rameters in female handball players. Twenty female handball players (experimental group: 10; control group: 10) voluntarily participated in the studyThe experimental group trained in high-intensity interval training (HIIT) 3 days a week for 8 weeks in addition to handball training, while the control group was allowed to continue their standard training program. The anaerobic capacity, speed, and agility of the experimental and control groups were measured twice before and after an 8-week training program. The HIIT training program for the experimental group was adapted to the movements most commonly used in handball. The values of the data obtained from the handball players were analyzed. ANOVA for mixed measures was applied to determine the difference between the pre-test and post-test values of the experimental and control groups. There was a statistically significant difference (p &lt; 0.05) between the pre and post-test values of the 20-m sprint test of the experimental and control groups of HIIT training for handball players, while there was no statistically significant difference between the pre and post-test values of the anaerobic capacity and agility test of HIIT training. In conclusion, it is recommended to include HIIT training in the training periodization of handball players during the season, and it is believed that it will have a positive effect on players' speed performance.

The Effectiveness of Using Minimal Pairs towards Students' Pronunciation Mastery

Pronunciation is essential in communication It can avoid misunderstandings. However, many students have difficulty pronouncing English words. Students in the eleventh grade of SMA Nur El Falah had problems with pronunciation. This research aimed to determine whether minimal pairs is effective towards students’ pronunciation mastery at the eleventh grade of SMA Nur El Falah. This research was located at SMA Nur El in Kubang, Serang District. This research's sample comprised forty-four eleventh-grade students. This research employed a quantitative method using a quasi-experimental with a non-equivalent (Pre-test and Post-test) control group design. The data collecting technique used testing (pre- and post-test), recording, and documenting. The data analysis technique used was statistical calculation analysis using IBM SPSS 25. The findings revealed that minimal pairs was effective towards students’ pronunciation mastery at the eleventh grade of SMA Nur El Falah. It was demonstrated by the value of the Man Whitney-U test that showed 0.000 &lt; 0.05 means alternative hypothesis was accepted. Therefore, this indicated that minimal pairs was effective towards students’ pronunciation mastery at the eleventh grade of SMA Nur El Falah.

Qualitative Fecal Immunochemical Test as a Screening Test for Colorectal Cancer

Colorectal cancer is one of the most common cancers, causing mortality, morbidity, and economic burden. Patient survival differs due to differences in access to health facilities, as well as diagnostic and therapeutic modalities. Early detection can allow colorectal cancer to be diagnosed at an earlier stage, improving patient outcomes and lowering mortality. Due to the lack of a national screening program in Indonesia, as well as the uneven availability of colonoscopy tools, the fecal immunochemical test has become the preferred screening method. This cross-sectional study aims to validate the application of the fecal immunochemical test for colorectal cancer detection. Fecal immunochemical test examination is performed on all patients with suspected colorectal cancer who will undergo a colonoscopy examination at Prof. Hospital dr. I.G.N.G. Ngoerah, Bali, Indonesia. Histopathological examination is used to diagnose colorectal cancer. This study included 78 people with a colorectal cancer prevalence of 40.91%. There were 38(57.6%) subjects with positive fecal immunochemical test results in this study, and 25(65.6%) of them were diagnosed with colorectal cancer. The sensitivity, specificity, positive predictive value, and negative predictive value of the qualitative fecal immunochemical test in detecting colorectal cancer were 92.59%, 66.67%, 65.79%, and 92.86%, respectively. The qualitative fecal immunochemical test has high sensitivity and can be used as an objective and accurate method of screening symptomatic patients with suspected CRC for colonoscopy.

Analysis of Therapy Satisfaction on the Quality-of-Life of Type 2 Diabetes Mellitus Patients at Anutapura Hospital Palu

Background: Type 2 Diabetes Mellitus (Type 2 DM) is a chronic disease characterized by increased blood glucose levels caused by impaired insulin function. In Palu City, Type 2 DM is the 2nd most common in Central Sulawesi with a total of 26,204 people. Objective: This study aims to determine the relationship between therapy satisfaction and the quality of life of Type 2 DM patients who perform outpatient treatment at Anutapura General Hospital, Palu. Methods: With a random sample approach, 100 respondents were used in this cross-sectional study that employed an observational method. Data collection used instruments in the form of a DMSAT (Diabetes Medication Satisfaction Tool) therapy satisfaction questionnaire and a DQOL (Diabetes Quality Of Life) quality of life questionnaire. Results: The results of the study were obtained on therapy satisfaction from Type 2 DM patients with the number of respondents in the very satisfied (1.0%), satisfied (90.0%), and quite satisfied (9.0%) categories while the results of the study of the quality of life of Type 2 DM patients 2 fall into the good category (38.0%), and the bad category (62.0%). The statistical analysis test used was the Spearman Rank Correlation test. The results of the Spearman Rank Correlation test value p = 0.037 or p &lt;α (0.05), then H0 is rejected, which means that there is a relationship between satisfaction with therapy and quality of life in patients with Type 2 DM which is very weak. Conclusion: The conclusion in this study is that there is a very weak relationship between therapy satisfaction and quality of life of patients.

Effect of Myofascial Therapy and Pelvic Relaxation Exercise Combined with Phonophoresis using Diclofenac Sodium gel in Myofascial Pelvic Pain Syndrome

Objective of The Study: To determine the effect of myofascial therapy and pelvic relaxation exercise combined with phonophoresis using Diclofenac sodium gel in subjects with myofascial pelvic pain syndrome (MPPS). Background of The Study: Myofascial pain syndrome is a disease that is characterized by hypersensitive point called trigger points found in one or more muscles and connective tissue. Myofascial Pelvic Pain Syndrome (MPPS) is a source of chronic pelvic pain in women. This pain can be continuous or episodic. This study is designed to compare the effects of interventions namely myofascial therapy and pelvic relaxation exercise combined with phonophoresis using Diclofenac sodium in subjects with MPPS. Methodology: This experimental study was conducted among 20 subjects at Faculty of Physiotherapy, Dr. M.G.R Educational and Research Institute. Study duration was 4 weeks. Subjects were selected by simple random sampling method. The subjects were selected based on Inclusion and exclusion criteria.Outcome measures included were visual analogue scale (VAS), Pelvic pain impact questionnaire (PPIQ), SF-36 questionnaire. Procedure: 20 female subjects with myofascial pelvic pain syndrome were randomly divided into two groups. Group A (n=10) subjects were treated with myofascial therapy. Group B (n=10) subjects were treated with pelvic relaxation exercise. Treatments for both the groups were given for 3 days in a week for 4 weeks. Results: On comparing the pre and post values within experimental group, it shows statistically significant improvement on visual analogue scale score (P ≤ 0.05) andPPI questionnaire score (P ≤ 0.05) and also in pre and post test values of experimental groups, it reveals significant difference on short form survey – 36 score (P ≤ 0.05)

Effectiveness of natural clay therapy on level of pain among women with knee osteoarthritis admitted in selected hospital at Tiruvannamalai

A quasi experimental study was carried out in government medical college and hospital at Tiruvannamalai to evaluate the natural clay therapy on pain among women with knee osteoarthritis (OA). A total 60 samples were selected by using non-probability convenience sampling technique and the sample was equally divided into Experimental Group (30) and Control Group (30). The natural clay was applied 30 minutes per day for seven days to the experimental group and control group received routine care. Data was collected before and after intervention by structured questionnaire containing demographic variables, and intensity of pain was assessed by using visual analog scale. The study results revealed that the pre test mean score of pain in experimental group was 13.53 with S.D 1.19 and control group was 13.17 with S.D 1.15. The calculated unpaired ‘t’ test value t= 1.19 was found to be statistically not significant. The post-test mean score of pain in experimental group was 9.12 with S.D 1.18 and control group was 13.93 with S.D 1.14 The calculated unpaired ‘t’ test value t= 16.05 was statistically significant at p&lt;0.001 level. The study concluded that the natural clay therapy was effective in reduction of pain among women with osteoarthritis in experimental group then the control group. As a natural element it does not show any side effects which is also available and affordable at near reach and improves quality of life of women with knee osteoarthritis.

Effectiveness of consuming celery leaf juice in reducing high blood pressure in elderly

Celery is an annual plant in the form of a bush or grass. In everyday life celery is usually used as a complement to food. Hypertension is also a cause of death with a figure of 23.7% of the total 1.7 million deaths in Indonesia in 2016. One of the non-pharmacological measures that can be taken to lower blood pressure in people with high blood pressure is celery leaf juice. This study aims to determine the effectiveness of consuming celery leaf juice in reducing high blood pressure in the elderly at the Rejosari Health Center, Pekanbaru City. This type of research is quasi-experimental with a one group pretest posttest design. The population of 3,546 people affected by high blood pressure at the Rejosari Health Center in Pekanbaru City in 2021 with a sampling technique using purposive sampling with a total of 12 samples. The instrument used is the observation sheet. Univariate and bivariate data analysis, data processing using the dependent t test. The results showed that there was an effectiveness of consuming celery leaf juice in reducing high blood pressure in the elderly, the dependent t test value was p value 0.039 so that the p value was 0.05 then H0 was rejected, which means there was effectiveness in consuming Celery leaf juice as a non-pharmacological therapy in reducing high blood pressure in the elderly. Based on the results of this study it is expected to be able to consume celery leaf juice regularly and maintain a diet to help reduce or control blood pressure.

Recall and recognition of similarities items in neuropsychological assessment: Memory, validity, and meaning

The current study examined whether the Memory Similarities Extended Test (M-SET), a memory test based on the Similarities subtest of the Wechsler Abbreviated Scale of Intelligence, Second Edition (WASI-II), has value in neuropsychological testing. The relationship of M-SET measures of cued recall (CR) and recognition memory (REC) to brain injury severity and memory scores from the Wechsler Memory Scale, Fourth Edition (WMS-IV) was analyzed in examinees with traumatic brain injuries ranging from mild to severe. Examinees who passed standard validity tests were divided into groups with intracranial injury (CT + ve, n = 18) and without intracranial injury (CT-ve, n = 50). In CT + ve only, CR was significantly correlated with Logical Memory I (LMI: rs = .62) and Logical Memory II (LMII: rs = .65). In both groups, there were smaller correlations with delayed visual memory (VRII: rs = .38; rs = .44) and psychomotor speed (Coding: rs = .29; rs = .29). The REC score was neither an indicator of memory ability nor an internal indicator of performance validity. There were no differences in M-SET or WMS-IV scores for CT-ve and CT + ve, and reasons for this are discussed. It is concluded that M-SET has utility as an incidental cued recall measure.

Effect of Dorzolamide-Timolol fixed dose combination on central Corneal Thickness in patients of Primary Open Angle Glaucoma Versus Normal Tension Glaucoma

PURPOSE: To evaluate the effect of dorzolamide/timolol fixed dose combination on central corneal thickness in primary open-angle and normal tension glaucoma. METHOD: This retrospective cohort study was approved by the Ethical Review Board of College of Ophthalmology and Allied vision Sciences (1469/23) and was conducted at Diagnostic clinic Mayo Hospital, Lahore from March, 2023 to September, 2023. Sample size was calculated by a formula whose level of significance (????) was 5%, standard deviation (????) 30.9 and test values of population mean (µ̥) was 540. Using non-probability convenient sampling method total sample size was 80 patients of age group 30 to 60 which divided into normal tension and primary open angle glaucoma of 40 each. Patients with corneal edema, diabetes, and allergic to dorzolamide-timolol fixed dose combination were excluded. Data was analyzed using SPSS version 25.00. Wilcoxon signed ranks test and chi-square test were used for the significance of the study. Data p-value &lt;0.005 considered significant. All the tests were performed after patient’s informed consent. Intraocular pressure (IOP) and central corneal thickness (CCT) were measured by Goldmann applanation tonometer and ultrasound Pachymeter respectively. RESULTS: IOP and CCT in right eye 16.17± 7.05 (p=0.000) and 545.50± 22.2 (p=0.098) respectively and of left eye 16.56± 7.00 (p=0.003) and 549.16± 20.0 (p=0.133) respectively. This illustrates significant difference in intraocular pressure after treatment in both eyes but insignificance difference in central corneal thickness. CONCLUSION: Dorzolamide-Timolol combination successfully reduces IOP as intended and leads to no statistically significant change in central corneal thickness.

Diagnostic value of IgG antibody and stool antigen tests for chronic Helicobacter pylori infections in Ibb Governorate, Yemen

The stool antigen test (SAT) and the serum Helicobacter pylori (H. pylori) IgG antibody assays exhibit significant utility in the clinical diagnosis of H. pylori infection and in distinguishing between acute and chronic infections. The main objective of the current study was to identify the diagnostic value of serum H. pylori IgG antibody and SAT in the detection of H. pylori infections among chronic H. pylori-infected patients residing in Ibb Governorate, Yemen. 200 patients with H. pylori infection, confirmed through positive results in the serum immunochromatographic antibody test, were selected for H. pylori infection confirmation using serum H. pylori IgG antibodies and SAT across diverse hospitals, gastroenterology, and Hepatology clinics in Ibb Governorate. After the selection of patients, blood and stool specimens were obtained from all participants and underwent analysis via the Statistical Package for the Social Sciences (SPSS). The prevalence of H. pylori infection demonstrated variability based on the confirmatory tests, with rates of 54% for SAT and 78.5% for serum H. pylori IgG antibody, contrasting with a 100% prevalence observed in the screening serum immunochromatographic antibody test. Clinically, the study categorized H. pylori infections into four stages, whereby a significant proportion of patients (40.5%) exhibited positivity for both serum H. pylori IgG antibody and SAT, indicative of active chronic infections. The majority of positive cases only manifested serum H. pylori IgG antibody presence (chronic infections) at 38%, whereas 13.5% exclusively tested positive for SAT, corresponding to acute infections. Moreover, 88% of patients did not have either serum H. pylori IgG antibody or SAT (absence of infections) during confirmatory tests. Noteworthy is the study's approach employing multiple tests for H. pylori infection detection, focusing predominantly on chronic infections-prevailing types caused by H. pylori. The results revealed a significant association between serum levels of H. pylori IgG antibody and SAT results with the presence of diverse gastrointestinal symptoms among patients, which increased with long H. pylori infection durations.

Psychomotor retardation: What about the partial responders to magnetic transcranial stimulation in treatment resistant depression ?

ObjectivePsychomotor retardation is a core clinical component of Major Depressive Disorder responsible for disability and is known as a treatment response marker of biological treatments for depression. Our objective was to describe cognitive and motoric measures changes during a treatment by repetitive Transcranial Magnetic Stimulation (rTMS) within the THETAD-DEP trial for treatment-resistant depression (TRD), and compare those performances at the end of treatment and one month after between responders (>50% improvement on MADRS score), partial responders (25–50%) and non-reponders (no clinically relevant improvement). Our secondary aim was to investigate baseline psychomotor performances associated with non-response and response even partial. MethodsFifty-four patients with treatment-resistant unipolar depression and treated by either high frequency 10 Hz rTMS or iTBS for 4 weeks (20 sessions) underwent assessment including French Retardation Rating Scale for Depression (ERD), Verbal Fluency test, and Trail Making Test A. before, just after treatment and one month later. Results20 patients were responders (R, 21 partial responders (PR) and 13 non-responders (NR). rTMS treatment improved psychomotor performances in the R and PR groups unlike NR patients whose psychomotor performance was not enhanced by treatment. At baseline, participants, later identified as partial responders, showed significantly higher performances than non-responders. ConclusionHigher cognitivo-motor performances at baseline may be associated with clinical improvement after rTMS treatment. This work highlights the value of objective psychomotor testing for the identification of rTMS responders and partial responders, and thus may be useful for patient selection and protocol individualization such as treatment continuation for early partial responders.