Utrecht University Research Articles

Scholars and Literati at the University of Utrecht (1636–1800)

This note is a summary description of the set of scholars and literati who taught at the University of Utrecht from its inception in 1636 to 1800. For more detailed information about these individuals, please visit the comprehensive database available at https://shiny-lidam.sipr.ucl.ac.be/scholars/.

DELirium treatment with Transcranial Electrical Stimulation (DELTES): study protocol for a multicentre, randomised, double-blind, sham-controlled trial.

Delirium, a clinical manifestation of acute encephalopathy, is associated with extended hospitalisation, long-term cognitive dysfunction, increased mortality and high healthcare costs. Despite intensive research, there is still no targeted treatment. Delirium is characterised by electroencephalography (EEG) slowing, increased relative delta power and decreased functional connectivity. Recent studies suggest that transcranial alternating current stimulation (tACS) can entrain EEG activity, strengthen connectivity and improve cognitive functioning. Hence, tACS offers a potential treatment for augmenting EEG activity and reducing the duration of delirium. This study aims to evaluate the feasibility and assess the efficacy of tACS in reducing relative delta power. A randomised, double-blind, sham-controlled trial will be conducted across three medical centres in the Netherlands. The study comprises two phases: a pilot phase (n=30) and a main study phase (n=129). Participants are patients aged 50 years and older who are diagnosed with delirium using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision criteria (DSM-5-TR), that persists despite treatment of underlying causes. During the pilot phase, participants will be randomised (1:1) to receive either standardised (10 Hz) tACS or sham tACS. In the main study phase, participants will be randomised to standardised tACS, sham tACS or personalised tACS, in which tACS settings are tailored to the participant. All participants will undergo daily 30 min of (sham) stimulation for up to 14 days or until delirium resolution or hospital discharge. Sixty-four-channel resting-state EEG will be recorded pre- and post the first tACS session, and following the final tACS session. Daily delirium assessments will be acquired using the Intensive Care Delirium Screening Checklist and Delirium Observation Screening Scale. The pilot phase will assess the percentage of completed tACS sessions and increased care requirements post-tACS. The primary outcome variable is change in relative delta EEG power. Secondary outcomes include (1) delirium duration and severity, (2) quantitative EEG measurements, (3) length of hospital stay, (4) cognitive functioning at 3 months post-tACS and (5) tACS treatment burden. Study recruitment started in April 2024 and is ongoing. The study has been approved by the Medical Ethics Committee of the Utrecht University Medical Center and the Institutional Review Boards of all participating centres. Trial results will be disseminated via peer-reviewed publications and conference presentations. NCT06285721.

ECO-MIND: enhancing pro-environmental behaviours and mental health through nature contact for urban youth – a research protocol for a multi-country study using geographic ecological momentary assessment and mental models

IntroductionUrban youth are experiencing increasing mental health problems due to diverse personal, social and environmental concerns. Youths’ detachment from natural environments, including green and blue spaces, may intensify such issues...

Introducing our Associate Editorial Board: An interview with Agathe Chaigne, Utrecht University, The Netherlands.

Introducing our Associate Editorial Board: An interview with Agathe Chaigne, Utrecht University, The Netherlands.

Da Vinci Project: Educating Sustainability Change-Makers with Transdisciplinary Challenge-Based Learning and Design Thinking.

Sustainability transitions need professionals with specific skills and attitudes that students often do not develop in their regular chemistry education. To foster sustainability change-maker competencies, we suggest augmenting higher education curricula, e.g., chemical degree programs, with transdisciplinary challenge-based learning combined with design thinking. The Da Vinci Project at Utrecht University (UU) in The Netherlands explores this approach, aiming to cultivate the undergraduates' sustainability change-maker competencies. After five years of experience, we reflected on the students' learning outcomes in this UU honors program. We conclude that transdisciplinary challenge-based education combined with design thinking provides unique opportunities for students to develop valuable skills and attitudes for navigating sustainability transitions, including the transition toward sustainable chemistry. These involve collaboration, communication, creative thinking, integrative problem-solving, stakeholder engagement, openness, empathy, the ability to deal with uncertainty and complexity, self-awareness, critical reflection, courage, and perseverance.

AI Eye-Tracking Technology: A New Era in Managing Cognitive Loads for Online Learners

Eye-tracking technology has emerged as a valuable tool for evaluating cognitive load in online learning environments. This study investigates the potential of AI-driven consumer behaviour prediction eye-tracking technology to improve the learning experience by monitoring students’ attention and delivering real-time feedback. In our study, we analysed two online lecture videos used in higher education from two institutions: Oxford Business College and Utrecht University. We conducted this analysis to assess cognitive demands in PowerPoint presentations, as this directly affects the effectiveness of knowledge dissemination and the learning process. We utilised a neuromarketing-research consumer behaviour eye-tracking AI prediction software called ‘Predict’, which employs an algorithm constructed on the largest neuroscience database (comprising previous studies conducted on live participants n = 180,000 with EEG and eye-tracking data). The analysis for this study was carried out using the programming language R, followed by a series of t-tests for each video and Pearson’s correlation tests to examine the relationship between ocus and cognitive demand. The findings suggest that AI-powered eye-tracking systems have the potential to transform online learning by providing educators with valuable insights into students’ cognitive processes and enabling them to optimise instructional materials for improved learning outcomes.

Knowledge domain and emerging trends in the rupture risk of intracranial aneurysms research from 2004 to 2023.

Intracranial aneurysms (IAs) pose significant health risks, attributable to their potential for sudden rupture, which can result in severe outcomes such as stroke and death. Despite extensive research, the variability of aneurysm behavior, with some remaining stable for years while others rupture unexpectedly, remains poorly understood. To employ bibliometric analysis to map the research landscape concerning risk factors associated with IAs rupture. A systematic literature review of publications from 2004 to 2023 was conducted, analyzing 3804 documents from the Web of Science Core Collection database, with a focus on full-text articles and reviews in English. The analysis encompassed citation and co-citation networks, keyword bursts, and temporal trends to delineate the evolution of research themes and collaboration patterns. Advanced software tools, CiteSpace and VOSviewer, were utilized for comprehensive data visualization and trend analysis. Analysis uncovered a total of 3804 publications on IA rupture risk factors between 2006 and 2023. Research interest surged after 2013, peaking in 2023. The United States led with 28.97% of publications, garnering 37706 citations. Notable United States-China collaborations were observed. Capital Medical University produced 184 publications, while Utrecht University boasted a citation average of 69.62 per publication. "World Neurosurgery" published the most papers, contrasting with "Stroke", the most cited journal. The PHASES score from "Lancet Neurology" emerged as a vital rupture risk prediction tool. Early research favored endovascular therapy, transitioning to magnetic resonance imaging and flow diverters. "Subarachnoid hemorrhage" stood out as a recurrent keyword. This study assesses global IA research trends and highlights crucial gaps, guiding future investigations to improve preventive and therapeutic approaches.

P-095 Towards deciphering the molecular architecture of the human sperm connecting piece

Abstract Study question How can we make the human sperm connecting piece accessible for structural analysis by cryo-electron tomography (cryo-ET)? Summary answer Preparation of sperm by chemical thinning or production of lamellae via cryo-focused ion beam (cryo-FIB) milling allows direct imaging of the human sperm connecting piece. What is known already Previous studies from our group and others have demonstrated the versatility of cryo-ET to advance our understanding of sperm biology. Structures of macromolecular complexes have been resolved in vitro and in situ, enabling a functional assessment at molecular or even atomic level. Resolving structures at high resolution further allowed identification of proteins previously not known to have a role in mediating male fertility. Such insights are instrumental to further improve diagnosis and treatment of male infertility. Study design, size, duration In our research study we use sperm samples from patients undergoing IVF treatment or donor material, which we receive through an ongoing collaboration with the Division of Woman and Baby, University Medical Centre Utrecht (UMCU). These samples are processed in our own laboratory and subsequently imaged by cryo-ET at the Electron Microscopy Centre of Utrecht University. Participants/materials, setting, methods Due to its thickness, the connecting piece cannot be directly analyzed by cryo-ET. Thus, we designed two strategies to achieve thinning of this area and allow collection of tomograms for structural analysis. While the first approach involves incubation of sperm with a detergent, a reducing agent and heparin, the second approach utilizes cryo-FIB milling to produce thin lamellae of the connecting piece. Main results and the role of chance Both strategies developed to access the connecting piece with cryo-ET are effective and allowed us a glimpse of the molecular landscape of the link between sperm head and tail. Chemical thinning of the connecting piece enabled imaging of the proximal and distal centriole while still embedded in the segmented columns or outer dense fibers, respectively. Furthermore, electron density within the microtubules of both centrioles indicates that they are decorated by microtubule inner proteins. Data obtained from lamellae produced by cryo-FIB milling complements these findings, displaying regular densities along the microtubules extending from the proximal centriole. Analyzing tomograms collected from cryo-FIB lamellae we further found a regular protein density that appears to be connecting the nuclear envelope to the base plate. Moreover, cryo-ET of lamellae allowed a detailed view of nuclear pore complexes and the postacrosomal sheath in their native environment. Limitations, reasons for caution Altering the native state of the sperm cell by chemical preparation is a limitation of this approach. Cryo-FIB milling retains the native state of the cell but is limited in throughput. To improve our cryo-FIB milling approach, we will implement automated milling procedures. Wider implications of the findings Chemical preparation and cryo-FIB milling of sperm enable the in-depth analysis of the connecting piece by cryo-ET. These strategies can now be applied to provide structural details at the molecular level and thus advance our understanding of male infertility related to defects of the head-tail junction. Trial registration number not applicable

Extraction of Knowledge Models from Textbooks

Isaac Alpizar-Chacon is an assistant professor in the Software Technology for Learning and Teaching group at the Department of Information and Computing Sciences, Utrecht University. In addition to his primary role, he is also an associate professor at the Instituto Tecnológico de Costa Rica. His research interests focus on the impact of GenAI tools in computing education, the integration of these tools into the classroom, the teaching and learning of computational thinking skills, and knowledge extraction. Dr. Alpizar-Chacon holds a MSc degree in Computer Science from Saarland University (Saarbrücken, Germany) and a PhD degree in Information and Computing Sciences from Utrecht University (Utrecht, Netherlands). Homepage: https://isaacalpizar.info/

Owners' experiences of administering meglumine antimoniate injections to dogs with leishmaniosis: An online questionnaire study.

This study examined the experiences of owners of dogs with leishmaniosis who treated their dogs with daily subcutaneous meglumine antimoniate injections. The owners' perceived ease of administering the injections, the occurrence of problems and the effects on the owners and on the dog‒owner bond were evaluated. Dogs prescribed meglumine antimoniate as a treatment for leishmaniosis were identified using the database of the veterinary pharmacy of the Faculty of Veterinary Medicine, Utrecht University. An online questionnaire was sent to the owners of these dogs to evaluate the perceived ease of administering the injections, the occurrence of problems and the effects on the owner and the dog-owner bond. Responses were received from 64 dog owners. Most respondents (78%) reported that administering the injections was not difficult. Pain or the development of nodules at the injection site was reported in 50% and 40% of the dogs, respectively. Polyuria was reported in 44% of the dogs. Some owners reported that administering the injections had a negative impact on their psychological wellbeing (20%), and some would have liked more veterinary support (11%). Some questions were answered by a limited number of people, and their responses may not be representative. Dog owners remain highly motivated to persevere with meglumine antimoniate treatment and are willing to administer the injections themselves. The availability of active support when needed during the therapy cycle may further improve their acceptance of and confidence in giving the injections.

#1920 The impact of kidney function on cardiac diastolic dysfunction trajectories: insights from a longitudinal study

Abstract Background and Aims Although the association between kidney dysfunction and cardiac diastolic dysfunction has been investigated in cross-sectional studies, we currently lack a complete understanding of how the diastolic dysfunction changes over time in individuals with different kidney functions. Exploring the diastolic dysfunction trajectories is crucial as it can provide valuable insights into how kidney function influences cardiac health and which patients are at the highest cardiovascular risk. E/e’ is an echocardiography measure that estimates left ventricular filling pressure and diastolic dysfunction. This study evaluates how kidney function impacts changes in E/e′ over time. Method We identified patients from the Utrecht Patient Oriented Database (UPOD) who visited the outpatient clinic of Utrecht University Medical Center between January 2012 and April 2022. Patients who had received at least three echocardiography reports with a minimum of 12 months between them and had recorded serum creatinine measurements in their electronic health records were included. The estimated glomerular filtration rate (eGFR [mL/min/1.73 m2]) was calculated using the CKD-EPI 2021 creatinine formula without ethnicity and categorized as follows: eGFR ≥ 90, eGFR ≥ 60 - <90, eGFR < 60. Linear mixed-effect models were utilized to determine the impact of kidney function on changes in E/e′ over time. Results A total of 436 patients were included of whom 34.7% were women. The total number of echocardiography examination was 1308. Overall, the median eGFR for all patients was 78.2 mL/min/1.73 m2 [IQR: 61.9, 90.7]. Among them, 26.6%, 51.4%, and 22.0%, had an eGFR ≥ 90, eGFR ≥ 60 - < 90, and eGFR < 60, respectively. Patients with an eGFR < 60 had a higher prevalence of hypertension (64.6%) and cardiovascular disease (84.4%) compared to those with an eGFR ≥ 90, where the prevalence of hypertension and cardiovascular disease was 49.1% and 67.2%, respectively. Additionally, patients with an eGFR < 60 had the lowest mean ejection fraction of 44.9% ± 18.5% and the highest median E/e′ of 12.84 [10.10, 16.16]. The linear mixed model analysis showed that the estimated change in E/e′ per year depended on the level of kidney function. For patients with eGFR ≥ 60 - <90, E/e′ did not significantly change per year (p-value: 0.927). However, for patients with eGFR < 60, a statistically significant (p = 0.014) increase in the E/e′ of 0.45 (0.09, 0.81) was observed per year. Hypertension, diabetes mellitus, and cardiovascular disease were found to affect the change in E/e′, with estimates of 0.95 (0.41, 1.49), 1.82 (0.82, 2.89), and 1.25 (0.54, 1.97), respectively. Conclusion The trajectory of changes in E/e′ over time was significantly affected by varying levels of kidney function. Patients with impaired kidney function (eGFR < 60) have a higher E/e’ compared to those with normal kidney function (eGFR ≥ 90) and presented a significant increase of E/e’ per year.

Extraction, purification, and clumped isotope analysis of methane (Δ13CDH3 and Δ12CD2H2) from sources and the atmosphere

Abstract. Measurements of the clumped isotope anomalies (Δ13CDH3 and Δ12CD2H2) of methane have shown potential for constraining methane sources and sinks. At Utrecht University, we use the Thermo Scientific Ultra high-resolution isotope-ratio mass spectrometer to measure the clumped isotopic composition of methane emitted from various sources and directly from the atmosphere. We have developed an extraction system with three sections for extracting and purifying methane from high (> 1 %), medium (0.1 % to 1 %), and low-concentration (< 0.1 %) samples, including atmospheric air (∼ 2 ppm = 0.0002 %). Depending on the methane concentration, a quantity of sample gas is processed that delivers 3 ± 1 mL of pure methane, which is the quantity typically needed for one clumped isotope measurement. For atmospheric air with a methane mole fraction of 2 ppm, we currently process up to 1100 L of air. The analysis is performed on pure methane, using a dual-inlet setup. The complete measurement time for all isotope signatures is about 20 h for one sample. The mean internal precision values of sample measurements are 0.3 ± 0.1 ‰ for Δ13CDH3 and 2.4 ± 0.8 ‰ for Δ12CD2H2. The long-term reproducibility, obtained from repeated measurements of a constant target gas, over almost 3 years, is around 0.15 ‰ for Δ13CDH3 and 1.2 ‰ for Δ12CD2H2. The measured clumping anomalies are calibrated via the Δ13CDH3 and Δ12CD2H2 values of the reference CH4 used for the dual-inlet measurements. These were determined through isotope equilibration experiments at temperatures between 50 and 450 °C. We describe in detail the optimized sampling, extraction, purification, and measurement technique followed in our laboratory to measure the clumping anomalies of methane precisely and accurately. This paper highlights the extraction and one of the first global measurements of the clumping anomalies of atmospheric methane.

Analysing the effect of a dynamic physical environment network on the travel dynamics of forcibly displaced persons in Mali

Article Analysing the effect of a dynamic physical environment network on the travel dynamics of forcibly displaced persons in Mali Boesjes Freek 1, Jahani Alireza 2, Ooink Bas 3, and Derek Groen 2,* 1 Utrecht University, Heidelberglaan 8, Utrecht, Utrecht 3584 CS, the Netherlands 2 Computer Science Department, Brunel University London, Wilfred Brown Building, Kingston Lane, Uxbridge UB8 3PH, UK 3 Blue Team Intelligence, Jan Aertshof 3, Hoevelaken 3871 WH, the Netherlands * Correspondence: Derek.Groen@brunel.ac.uk Received: 7 September 2023 Accepted: 30 January 2024 Published: 26 March 2024 Abstract: As of 2023, the world has approximately 100 million refugees, many of whom have been displaced by violent conflicts. Accurately predicting where these people may go can help non-government organisations (NGOs) and other support organisations to more effectively help these refugees. In this paper, we extend the existing flee migration forecasting model which models migration using intelligent agents with a dynamic network that represents the physical environment. In doing so, we integrate time-dependent data into four different characteristics from three public data sources. We obtain data from aspects such as the slope, drainage, soil and infrastructure, and use these aspects to systematically modify the movement preferences of forcibly displaced agents in the flee model. We showcase our approach by applying it to the 2012 northern Mali conflict. We find that numerous routes previously deemed traversable are actually inaccessible for prolonged periods according to sensor data, and a range of off-road routes are instead traversable for vehicles. We also perform a validation comparison with the original modelling approach, and find that our revised representation of travel routes leads to a reduction of 4.5% in the averaged relative difference. Our approach can be reused in other flee conflict contexts, of which five are present in the EU-funded ITFLOWS project alone. Our work provides the ability to represent a dynamic physical environment and potentially improves the simulation accuracy in a range of flee conflict situations.

Exploring the entrepreneurial landscape of university-industry collaboration on public university spin-off creation: A systematic literature review

Research into the factors influencing university-industry collaboration on public university spin-offs creation has focused on management, entrepreneurship, technology and innovation. This research began with a careful systematic literature review of 4427 scientific papers published in the last ten years (2014–2023) and accessible in the prestigious Web of Science core collection. A quantitative methodology was used, complemented by the use of the visual analysis tool Posit PBC™, formerly known as R Cloud Studio. This comprehensive approach facilitated the seamless ingestion of raw data into Biblioshyni, which is a web-based platform specialised in bibliometric analysis. This review has revealed compelling trends, particularly in terms of increasing diversity, the emergence of United Kingdom as a major player, and the central role of university-industry collaboration. Our systematic review identified influential authors in the field, including the prolific contributions of scholars such as D. Radicid, S. Ropers, Y. Li and R. Owen. We also identified important research institutions, such as Utrecht University in Netherlands, Lund University in Sweden and The University of Manchester in the UK. In addition, we have shown that countries such as the United Kingdom, China and USA have made a significant contribution to the volume of publications. The results highlighted a marked increase in the phenomenon of univeristy spin-offs over the past decade, as evidenced by the exponential growth in both publication output and citation rates. This empirical revelation was underpinned by a rigorous exploration of the Web of Science database, using a carefully crafted set of keywords. Thirty-seven pivotal studies were selected for in-depth review through a sophisticated selection process that adhered to the rigorous standards of the PRISMA methodology. The aim of this review is to improve understanding and encourage deeper exploration of spin-off-based public universities through collaboration between academia and industry.

First person – Celia Segui-Perez

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Celia Segui-Perez is first author on ‘ MUC13 negatively regulates tight junction proteins and intestinal epithelial barrier integrity via protein kinase C’, published in JCS. Celia is a PhD student in the lab of Karin Strijbis at the Department of Biomolecular Health Sciences, Utrecht University, The Netherlands, investigating the role of mucins in health and disease.

SIM Peter Baehr lecture 2023: Human rights and the International Court of Justice

The annual SIM Peter Baehr lecture celebrates the founding of the Netherlands Institute of Human Rights (SIM) in 1981 and commemorates the late Peter Baehr, one of SIM's former directors and an eminent human rights scholar. The 2023 lecture was delivered at Utrecht University on 30 November by Hilary Charlesworth, judge at the International Court of Justice and renowned scholar of international law and human rights.

Preface

Disaster Research Center Universitas Sebelas Maret successfully held the 2nd International Conference on Disaster Management and Climate Change 2023 (ICoDMC 2023) via the online Zoom system on August 12 2023. ICoDMC 2023 aims to disseminate research results and various ideas regarding controlling environmental damage and disaster management for a better life and provide input to the government and other policy-making institutions in the environment and disaster management field. The theme for 2023 is Climate Changes and Hydrometeorological Disaster Mitigation.ICoDMC 2023 invites great speakers who are highly competent in natural disasters and disaster environments, and they are Prof. Ir. Dwikorita Karnawati, M.Sc. PhD (Head of the Meteorology, Climatology and Geophysics Agency), Prof. Christopher Andre Gomez (Department of Maritime Sciences, Kobe University, Japan), Ahmad Marzuki, S.Sc. Ph.D (Sebelas Maret University, Indonesia), Prof. Dr. Martin Coy (Institut Für Geographie, Universität Innsbruck, Austria), and Dr. Annisa Triyanti (Utrecht University, Netherlands).The topic of this seminar is Climate Changes and Ecology, Disaster Mitigation, Disaster Risk Reduction, Environmental Risk Assessment Infrastructure for Disaster, Natural Resources, Natural and Non-Natural Disaster, Oceanography and Coastal Problems, Water and Hydrology, and Spatial Planning for Disaster. There were 198 articles submitted according to the topic above, and after selection, selected 135 articles were presented and submitted to the IOP-EES Proceedings. The article’s authors include lecturers, practitioners, teachers, and students. Two hundred twenty-six participants joined the seminar.Thank you to all speakers, authors and participants. See you at the third ICoDMC.RegardsProf. Dr. Chatarina Muryani, M.SiChairman of the committee Committee 2nd International Conference on Disaster Management and Climate Changes (ICoDMC 2023) List of Steering Committee, Conference Chair, Conference Vice Chair, Secretary, Editor are available in this pdf.

Bibliometric Analysis of Research Hotspots and Frontiers in Progress towards the Sustainable Development Goals

The United Nations Sustainable Development Goals (SDGs), established in 2015, are binding targets for monitoring the sustainable status of all countries in the world. Developing localized SDGs indicator systems, assessing SDGs progress comprehensively, and creating policy tools have gradually become the hotspots of scientific research and practical application of the SDGs. To systematically sort out the research status of the SDGs progress and identify problematic gaps, this paper uses bibliometric methods to analyse the scientific knowledge mapping of SDGs research, sort out the general characteristics, scientific cooperation, cutting-edge hotspots and future research trends of SDGs research. Besides, this paper promotes the integration of academic research into concrete practice by linking it to mainstream SDGs progress reports. The results show that: ① The amount of SDGs research literature in 2015–2022 is on a growing trend, and the existing research is characterised by multidisciplinary crossover. Research institutions such as Utrecht University, the Chinese Academy of Sciences, and the University of the Chinese Academy of Sciences have contributed the most to SDGs research. ② The research hotspots include the SDGs practice of different responsible subjects, the comprehensive assessment of the progress of SDGs, the scientific research of SDGs indicators, and the research on the interaction between the goals of SDGs. ③ Environmental issues, indicators, energy transition, education and agriculture are the hot directions of SDGs research. Energy saving and carbon reduction, sustainable practices of supply chain management, and promoting the progress of environmental dimension goals are the focus of subsequent research. According to the results of the bibliometric analysis, future SDGs research should pay attention to strengthening multi-party cooperation, using innovative technologies to support the assessment of SDGs progress, and formulating sustainable development strategies.

The Utrecht University Honours Program review project: example based scientific publishing training aimed at bachelor medical students

IntroductionMedical undergraduate students receive limited education on scholarly publishing. However, publishing experiences during this phase are known to influence study and career paths. The medical bachelor Honours Program (HP) at Utrecht University initiated a hands-on writing and publishing course, which resulted in nine reviews published in internationally peer reviewed academic journals. We wanted to share the project set-up, explore the academic development of the participating students and determine the impact of the reviews on the scientific community.MethodsThirty-one out of 50 alumni completed a digital retrospective questionnaire on for example, development of skills and benefit for their studies and career. Publication metrics of the HP review papers were retrieved from Web of Science.ResultsThis hands-on project provides a clear teaching method on academic writing and scholarly publishing in the bachelor medical curriculum. Participants were able to obtain and improve writing and publishing skills.The output yielded well-recognized scientific papers and valuable learning experiences. 71% of the participating students published at least one additional paper following this project, and 55% of the students indicated the project influenced their academic study and/or career path. Nine manuscripts were published in journals with an average impact factor of 3.56 and cited on average 3.73 times per year.DiscussionThis course might inspire other medical educators to incorporate similar projects successfully into their curriculum. To this end, a number of recommendations with regard to supervision, time investment and group size are given.

European Journal of Geography (Year 2023): Reviewer Appreciation & Publication Recap

European Journal of Geography (Year 2023): Reviewer Appreciation & Publication Recap