Use Of Computer Technology Research Articles

The Use of Computer Technologies in Special Education Teacher Training Programs in East Jerusalem: Students' Perspectives and Its Impact on Practical Applications"

Abstract: This research aims to explore the degree of use of computerized technologies in the special education teacher qualification program in East Jerusalem, and the extent of its impact on their performance in practical applications from the students’ point of view, explore students’ opinions about the effectiveness of computerized technologies in improving their educational experience and teaching skills, and reveal the differences in the use of computerized technologies. In qualifying special education teachers and its impact on their performance according to the variables of gender, number of years of experience, and experience in using computerized technologies, the descriptive approach was used, and the questionnaire was used as a tool for collecting data after ensuring its validity and reliability. The study population consisted of all students in special education teacher training colleges, numbering (680) teachers, distributed among 3 main colleges. The study sample consisted of (245) students selected by the available method, and the results were based on the reality of using computerized techniques in rehabilitation programs as a whole (3.80) and to a large degree, and the absence of statistically significant differences ( = 0.05) due to the effect of variables (gender, age, or experience in The use of computerized techniques) for the impact of the use of computerized techniques in the special education teacher qualification program in East Jerusalem on performance in practical applications from the point of view of students in all fields and the overall grade. Based on the results of the study, the researcher recommends strengthening the training of special education teachers within education teacher qualification programs. Specialize in the use of computerized technologies to ensure their effectiveness.

Software and Data Support for Computer Forensic Analysis

Introduction: the paper highlights the role of software and data support for computer forensic analysis carried out at the stage of judicial investigation and preliminary investigation, emphasizing its importance in the era of digitalization. Purpose: disclose the questions that modern technologies of computer-technical expertise are able to answer, and necessary data sets for research. Methods: the methodological framework for the study is based on the methods of consistency and analysis. Results: the paper presents a methodology for auditing computer equipment (CE) and information and communication technologies (ICT) in the context of criminal investigations. It also elucidates the techniques and methods employed in the study of CE and ICT hardware and software. Conclusions: the author analyzes the state of crime related to the use of computer technology in telematics networks and information and communication technologies, identifies ways to commit crimes related to the use of malware and legal software, the functioning of a dynamic system representing the mechanism of these crimes, as well as systemic aspects of the emergence and investigation of threats of this type.

Digital (mis)trust: ethnographic encounters with computational forms

ABSTRACT This special issue is driven by a curiosity about the role of computational forms – practices, logics, technologies, and infrastructures – in social life and how they mediate issues of trust and mistrust: designated (mis)trust. Through a series of ethnographic encounters, its contributors describe how (mis)trust is rendered as an issue of concern by various actors as it is problematized, conceptualized, narrated, and designed for. In doing so, the papers analyse the work (mis)trust does in these settings, with a focus on the role of computational thinking within public discourses on democratic elections, the use of computational technologies in establishing bureaucratic order, the computational practices at play in the production of coding subjectivities, and the computational artefacts that assure data circulations within digital infrastructures. This introduction argues for a more expansive understanding of the relation between trust and mistrust in the digital age, countering the oftentimes default rendering of these concepts as antonymic. Instead, it argues that they live in a mutable relation. Despite prevailing technosolutionist approaches to (mis)trust, it cannot, we suggest, be solved for, resolved, or even eviscerated. Whatever actors (engineers, programmers, professionals etc) do in their efforts to ‘fix’ mistrust, it continues to mutate as a social form.

Role Of Digital Image Processing In Education And Medical Field

Digital image processing is a technique that uses computer algorithms to analyze images and transform images into better ones.It is an important branch of Telecommunication engineering that deals with the improvisation of reliability and accuracy of the digital communication by employing multiple techniques. Image processing involves many processes such as taking images, preprocessing, image enhancement, transformation and analysis. Variations in pixel values are one of the major challenges faced by image processing. Digital Signal Processing is at the core of virtually all of today's information technology, and its impact is felt everywhere in telecommunications, medical technology, radar and sonar, and in seismic data analysis.Digital Image Processing plays an important role in medical field and education. Various researches has been done and currently popularly used. In education, pictures can be used to enhance student learning and to develop students’ self-esteem, or their utilization can be of little or no value and, if used carelessly, can, in fact, undermine students' self-confidence. Digital health technologies include both hardware and software solutions and services, including telemedicine, wearable devices, augmented reality, and virtual reality. Generally, digital health interconnects health systems to improve the use of computational technologies, smart devices, computational analysis techniques, and communication media to aid healthcare professionals and their patients manage illnesses and health risks, as well as promote health and wellbeing. Digital imaging gives healthcare providers better and more accurate images, which leads to establishing diagnoses sooner, making treatment of the patient more successful.

Disappearance of the face: From early photography to facial recognition systems

In this article I analyse the hidden genealogical link between portrait photography, used for criminological and psychiatric purposes, and contemporary systems of biometric identification of the human face. The aim is to highlight the shift between the emphasis on the importance of the human ‘expert eye’ in recognizing the face when talking about nineteenth-century photography and the use of computer technology that produces and reads digital facial images. In both cases, however, these are modes and variants of reducing and flattening the human face; the face itself disappears under the onslaught of technologies of vision and mediation, becoming a mere data set. Special attention is devoted to the pose, the frontal view, which is the technological a priori of the empirical possibility of recognition, articulated through the history of visualization of the face from early portrait photography to facial recognition systems. Consequently, what we call the ‘face’ is a simulacra of individual the face presented to the apparatus: the ‘real’ face is transposed upon multiple technological layers (camera – plates – photographic surface), losing its characteristic features to be re-written according to specific techniques of measurement.

THE EDUCATIONAL USE OF INTERACTIVE ELECTRONIC TEXTBOOKS IN PRIMARY FOREIGN LANGUAGE TEACHING

This article is devoted to the problem of developing foreign language communicative competence of primary school students on the basis of an interactive electronic textbook and provides an example of a training course developed based on an electronic textbook. The specificity of teaching a foreign language lies in the fact that students master the language in an artificial language environment due to the lack of a natural one. New information technologies are not only new technical means, but also new forms and methods of teaching, a new approach to the learning process. This situation involves the widespread use of computer technology and various technical teaching aids. The use of computer technology in foreign language lessons in primary school can be presented in different variations: working with specialized sites, watching authentic videos, etc. А very effective and relatively affordable method for teaching foreign languages is using of the electronic textbook. An electronic textbook allows you to implement the principles of a differentiated and individual approach to learning. Therefore, it is quite natural that in the teaching of a foreign language, new opportunities for using information and communication technologies have found a wide variety of applications. Despite the presence of various approaches to the problem of implementation new learning technologies in primary foreign language education, the educational use of electronic textbooks in primary ELT requires a more complete consideration.

Analisis Kepuasan Pengguna Aplikasi Manajemen Surat (AMS) di PT PLN (Persero) UP3 Palembang Menggunakan Metode End User Computing Satisfaction (EUCS)

The use of computer technology as an information technology tool for companies provides added value to the data processing process, the existence of information technology is also very useful for companies to facilitate performance in daily activities, especially as support in PLN official correspondence, both internal and external correspondence, starting from Service Notes, Letters, Special Form Letters and Legal Products. To keep up with technological advances, PT PLN (Persero) uses the Corporate Mail Management Application (AMS) to support business processes that provide an advantage for the company in achieving its goals. By using this application, PLN can manage letters automatically as well as manage electronic archives which benefits employees, thereby increasing the satisfaction of users of the application. User satisfaction with system performance is a benchmark for implementing information technology. This research uses the End User Computing Satisfaction (EUCS) method to determine user satisfaction of the Mail Management Application (AMS) at PT PLN (Persero) UP3 Palembang. The factors used in the EUCS method include Content, Format, Accuracy, Ease of Use, and Timeliness. Data collection was carried out by conducting a survey of 120 employees of PT PLN (Persero) UP3 Palembang, the results of which were analyzed using the IBM SPSS Version 25 application.

APPLICATION OF LINGUO-THEATRICAL APPROACH IN TEACHING FOREIGN LANGUAGES TO PEDAGOGICAL UNIVERSITY STUDENTS

Background. Professional training of a teacher traditionally includes elements of theater pedagogy as a condition for mastering professional pedagogical skills; it has a special role to play in the preparation of a future foreign language teacher. The ability for language self-education develops in conditions of a deficit of an authentic linguistic and cultural environment, which can only partly be compensated by the visualization of educational material and the use of computer technologies. The authors reveal the didactic potential of linguo-theatrical technologies, which make it possible to imitate linguocultural markers and models of the country of the target language and, thereby, contribute to the development of a multicultural linguistic personality in a student at a pedagogical university. The purpose of the study is to analyze the specifics of using theatricalization, dramatization and staging techniques in foreign language classes at a pedagogical university. Materials and methods. The main research method is a comparative analysis of sources that present a multi-paradigm description of the introduction of linguistic and theatrical elements into the process of teaching a foreign language. Quantitative and qualitative indicators were identified through the use of verbal communication methods (questionnaires and oral communication). Results. The verifiability of the research results was confirmed by the introduction of a set of communicative and theatrical tasks developed by the authors into practice to ensure the implementation of a linguistic and theatrical approach to teaching students of the Department of Foreign Languages at the KSPU named after V.P. Astafyev (Krasnoyarsk). The technique of theatricalization (stage or role-playing embodiment of the features of foreign language discourse) has the greatest didactic potential; the technique of dramatization (situational personification of characters) can be used to a lesser extent - this is explained by the need to have background knowledge of an authentic communicative situation; staging (stage production with the use of theatrical props) is characterized by the complexity of its implementation and increased labor intensiveness, both on the part of the teacher and on the part of the students, which, nevertheless generates increased interest and contributes to a more solid formation of language and speech skills.

The Role of Cloud Computing Technology in Supporting Educational Accessibility and Scalability

Education is very important for human life. Many of them are vying for the best education in the world to guarantee a better future. The thing that is very concerned about in Education is learning and also the right method of teaching, because that way it can give birth to a competitive and quality generation. One of them is the role of cloud computing technology, which is a combination of the use of computer technology and internet-based development. A way or method that makes it easy for users to access information without knowing what is in it, being expert with it or having control over it. Cloud computing is an important technology that has helped many institutions and schools use distance learning, and can support Education's accessibility and scalability. The purpose of this study is to determine the role of cloud computing technology in increasing the accessibility and scalability of more advanced education and being able to create a generation that is highly competitive and virtuous. The method used in this study uses a quantitative method by distributing questionnaires to respondents as many as 15 statements about the use of cloud computing technology in education. The results of this study proved to be a very effective role for cloud computing technology in improving education, because this technology can increase students' interest in learning and make them enthusiastic in learning, so as to create an interactive learning atmosphere. The implication of this latest technology is to make learning more interesting and easily accessible anytime and anywhere by students. Assignments can be collected online by utilizing various supporting educational platforms and application delivery of subject matter.

Determining the coordinates of unmanned aerial vehicles

The purpose of the work was to develop a method for determining unmanned aerial vehicles’ (UAVs) coordinates, trajectory and parameters of their spatial movements by means of kinematic projection. The paper analyses the use of technologies for determining coordinates and spatial movements of aircraft trajectories. The principle of the kinematic scheme of fixing moving objects by means of orthogonal and kinematic design has been developed. The principle scheme of determining UAV coordinates by kinematic projection was studied. The theoretical mathematical dependencies of the determination and calculations of the coordinates of spatial movements of unmanned aerial vehicles have been practically verified. The main object of research in this work was the theory of kinematic design as a means of graphically displaying the patterns of spatial movements of objects. The subject of the study was the specific features of searching and recording the trajectories of spatial movements of unmanned aerial vehicles in order to determine the coordinates of their instantaneous location in space. In the process of conducting theoretical and experimental research, methods and techniques of physical and mathematical modelling of fast-moving processes and mathematical statistics of analysis and classification of their results were used. The basis of the experimental study was the theory of mapping coordinates and trajectories of spatial movements of moving objects by means of graphic geometry when combining classical orthogonal design with dynamic features of kinematic design. For an objective assessment of the results of the theoretical and experimental study of the dynamics of objects moving in space, the classical theory of research planning with a mathematical apparatus for processing their results was used. Graphical models of UAV coordinate fixation were made with the use of computer technology and the AutoCAD graphic editor software.

Research and Practice on Instructional Methods for Piano Improvization Based on Computer Technology

In the backdrop of evolving technological landscapes, this paper delves into the utilization of computer technology, specifically Artificial Neural Networks (ANN), in enhancing piano improvisation instruction. Recognizing the growing demand for innovative teaching methods, our study aims to evaluate the practical effectiveness of ANN-based teaching evaluation in real-world piano improvisation settings. Through rigorous testing, we found that ANN demonstrates remarkable precision and consistency in assessing piano improvisation skills. In comparison to the traditional decision tree algorithm, ANN excels in managing complex nonlinear relationships, providing more accurate and reliable scoring results. This integration of technology not only elevates students’ performance but also fosters their musical creativity and perception. Our findings suggest potential improvements in refining instructional methodologies and expanding the use of computer technology in piano teaching. This underscores the importance of personalized teaching, blended learning models, and technical proficiency training for educators. Overall, our research methodologies and findings significantly contribute to advancing the modernization and technological progress of music education, equipping piano instructors with cutting-edge teaching tools and strategies.

System for monitoring building heat consumption

Relevance. Energy consumption and efficient use of district heating networks affect the environment, society and the economy. Solutions are needed that can significantly reduce specific thermal energy losses. Using a technically and economically feasible way to assess energy efficiency allows these decisions to be made. Currently, assessing the energy efficiency of buildings raises significant questions among specialists. There is not much modern specialized literature in this area. The problem of energy efficiency requires more rigorous attention to urban planning issues. Thus, refined methods for assessing the energy efficiency of buildings make it possible to simultaneously save capital investments and ensure efficient consumption of thermal energy. Aim. To develop a system for assessing the real heat consumption of buildings to ensure optimization of dispatching of centralized heat supply systems in real time. Methods. Computer modeling of the state of heat consumption of buildings with various characteristics and schemes for their connection to centralized heat supply networks; methods of geographic information analysis. Results. The authors have proposed the system for monitoring the heat consumption of buildings. This system allows assessing the energy efficiency of buildings through the maximum use of computer and software technologies. It is shown that the calculated heat flows of buildings used to predict savings when modernizing buildings do not always correspond to the actual heat loads, which can lead to an incorrect assessment of investment projects. The authors obtained graphical dependences of the quantities influencing specific heat losses on various primary independent factors. Conclusions. The constructed system for monitoring the heat consumption of buildings allows, together with the use of geoinformation analysis methods, obtaining a fairly complete picture of the state of heat consumption for city areas and an assessment of the energy characteristics of buildings.

The Effect of Computer-Supported Stem Applications on Secondary Students' Achievement and Computational Thinking Skills

In this study, the effect of STEM applications integrated with computer- supported materials on mathematics achievement in the subject of ratio-proportion and percentages was examined. In addition, it was aimed to reveal the effect of these applications on computational thinking skills. Furthermore, we aimed to reach the opinions of the experimental group students about the materials they used, STEM applications, and the application process. A mixed method was used with a sample consisting of 89 students in grade 7 of a secondary school. An achievement test, a scale of levels of computational thinking, and learning diaries were used as tools for data collection. The data were analyzed using t-test and content analysis. It was found that there was a significant difference between the experimental and control groups in terms of achievement in favor of the experimental groups. In terms of computational thinking, there was a significant difference in favor of the experimental groups, except for the creativity aspect of computational thinking skills. Based on the findings obtained with the computational thinking skills scale the study had a positive impact on most aspects of computational thinking. Accessed through the learning diaries students' views on learning with STEM applications were generally positive. In particular, the opinions on computer-supported materials pointed to a very satisfactory process. The findings suggest that the inclusion of STEM activities and the use of computer technology in education contribute to students' computational thinking skills and learning.

Bridging computer and education sciences: A systematic review of automated emotion recognition in online learning environments

Emotions play an important role in the learning process. With intelligent technology support, identification and intervention of learners’ cognition have made great achievement, but the care of emotion has been in the absence for a long time. In recent years, the use of affective computing technology to solve affective loss in online education has become a key research topic. To date, a growing number of studies have investigated automated emotion recognition (AER) in online environments. However, AER has been mainly studied from the perspective of computer science focusing on technical characteristics of developing AI technology while its pedagogical value and educational application has been overlooked. Therefore, this systematic literature review aimed to bring together educational and technical aspects of AER. Following PRISMA methodology, a comprehensive search of AER research from 2010 to 2024 in three databases (Web of Science, Science Direct and IEEE Xplore) identified 117 studies that met inclusion criteria. The articles were coded for report characteristics, educational characteristics (tech platform, pedagogy, assessment, content), technical characteristics (emotion model, emotion category, emotion measurement channel, database, algorithm model) and outcome characteristics (technical result, educational application). We found that the primary purpose of these studies was to develop and evaluate systems for AER, rather than implementing these systems in real online learning environments. Furthermore, our findings indicated a lack of integration between computer science and educational science in the realm of AER. Despite the fact that most algorithm models demonstrated high accuracy in AER, the interpretability of the results was significantly constrained by the quality of the databases used, along with the scarcity of studies focusing on the effective and real-time application of AER results. These findings provide essential guidance for shaping future research and development pathways in this field.

Enhancing Clinical Diagnosis With Convolutional Neural Networks: Developing High-Accuracy Deep Learning Models for Differentiating Thoracic Pathologies.

Background The use of computational technology in medicine has allowed for an increase in the accuracy of clinical diagnosis, reducing errors through additional layers of oversight. Artificial intelligence technologies present the potential to further augment and expedite the accuracy, quality, and efficiency at which diagnosis can be made when used as an adjunctive tool. Such techniques, if found to be accurate and reliable in their diagnostic acuity, can be implemented to foster better clinical decision-making, improving patient quality of care while reducing healthcare costs. Methodology This study implemented convolution neural networks to develop a deep learning model capable of differentiating normal chest X-rays from those indicating pneumonia, tuberculosis, cardiomegaly, and COVID-19. There were 3,063 normal chest X-rays, 3,098 pneumonia chest X-rays, 2,920 COVID-19 chest X-rays, 2,214 chest X-rays, and 554 tuberculosis chest X-rays from Kaggle that were used for training and validation.The model was trained to recognize patterns within the chest X-rays to efficiently recognize these diseases within patients to be treated on time. Results The results indicated a success rate of 98.34% incorrect detections, exemplifying a high degree of accuracy. There are limitations to this study. Training models require hundreds to thousands of samples, and due to potential variability in image scanning equipment and techniques from which the images are sourced, the model could have learned to interpret external noise and unintended details which can adversely impact accuracy. Conclusions Further studies that implement more universal database-sourced images with similar image scanning techniques, assess diverse but related medical conditions, and the utilization of repeat trials can help assess the reliability of the model.These results highlight the potential of machine learning algorithms for disease detection with chest X-rays.

Intermediate forms of musical art and new information technologies

The development of technology at the turn of the 20th century draws attention to the issues of connecting art with scientifi c achievements in the fi eld of acoustics, artifi cial intelligence, electronics, and sonorics. In the modern era, with the intensive development of science and technology, unexpected synthetic forms of combining genres are quite possible. The use of computer technology enriches the sound of the orchestra's acoustic instruments, exerting a strong psychoacoustic eff ect on the audience. Changing ideas about timbral sound and the desire to hear new intonations in the aesthetics of the 21st century expand the boundaries of the very concept of musical sound. The computer age has created a new aesthetic paradigm, which is based on the synthesis of technology and art. Modern ideas and experiments have created a sound space where acoustic tonal sounds, electronic sound timbres, and noises without a tonal basis coexist. Therefore, the boundaries of musical space in the sound fi eld also become very unstable and uncertain, and modern possibilities of theatricalization and visualization make the external boundaries of musical art even more unstable. Such genre fl exibility of boundaries is clearly manifested in the work of many modern composers. The materials of the article can be used in the educational process in areas of training related to the art of music.

Multimodal breast cancer risk classifier based on biomaterial impedance analysis

Purpose of the research. Breast cancer is the most common malignant tumor among women in Europe and its early detection plays a leading role in reducing mortality rates. Currently, X-ray mammography is the standard screening method for detecting breast cancer. However, due to the morphological similarities between benign and malignant lesions, many of the positive screening mammograms are false positive (up to 40%). Therefore, automation and intellectualization of this process is an urgent task.Methods. The presented studies examine the problems of finding new, highly sensitive, prompt and non-invasive methods for detecting malignant tumors, based on the use of modern computer and telecommunication technologies, which make it possible not only to identify early manifestations of a pathological focus, but also to monitor the process of the effectiveness of therapy without significant harm to the patient’s health.Results. The presented model of a multi-channel classifier integrates the capabilities of multi-frequency bioimpedance measurements and matrix acquisition of information from the surface of human skin through multi-electrode matrix systems. To do this, based on a matrix of electrodes, 3D mapping of the skin surface in problem areas is carried out. Through multi-frequency scanning, we obtain a three-dimensional bioimpedance image, which is analyzed by a convolutional neural network and/or by a decision maker. The proposed solution allows simultaneous analysis of data by an expert (bioimpedance image) and a convolutional neural network (trained classifier), which leads to a reduction in false positive results.Conclusion. The possibilities of multichannel monitoring open up prospects for constructing impedance multidimensional "portraits" of malignant tumors. To classify “portraits” (diagnostics and preclinical diagnostics), methods and algorithms for image recognition and classification are used.

THE INFLUENCE OF THE DEVELOPMENT OF COMPUTER TECHNOLOGIES ON THE PROCESS OF ARCHITECTURAL DESIGN

Problem statement. Computer technology is becoming increasingly popular in the architectural field, and its use can have both positive and negative consequences. Computer modeling allows architects to create and analyze designs faster and more accurately, which improves the quality and efficiency of construction. The development of computer technologies has significantly changed the approach to design in architecture. However, dependence on computer technologies can lead to the loss of the ability to analyze and design architectural objects independently. Purpose of the article. To analyze the impact of computer technology on architecture and to assess the perspective of this impact in the future. Conclusion. Today computer technology is used everywhere. The development of modeling and construction technologies provides new opportunities in the field of architecture. The use of computer technology at all stages of construction allows architects to create increasingly complex projects with high accuracy and efficiency. The use of new technologies in the field of architecture will allow to provide a more complex approach to design, which can cover more characteristics necessary to take into account. Generative design can be used to provide a more efficient and accurate design process. Virtual and augmented reality (VR and AR) provide a wide range of opportunities for designing and modeling architectural objects. With the help of BIM technology, an information model is created, which provides an accurate vision of the project as a whole. An important component of this technology is a single information space, a database. Artificial intelligence can create thousands of building options. The question of how to use resources more rationally (time, material, human) is one of the key issues of our time. Computer technologies help solve these problems and invent new methods of designing and building architectural objects. Ukraine, as one of the most digitized countries in the world, is rapidly introducing the latest technologies into the design work processes, which will lead to positive changes in the state's architectural image.

Teachers’ Attitude towards the Use of Computer Technology in Teaching English Vocabulary among Primary Schools in Nyamira County, Kenya

This paper investigated teachers’ perception towards use of computer technology for teaching and learning English vocabulary in primary schools in Nyamira County, Kenya. The researchers adopted the descriptive design and employed stratified simple random and purposive sampling techniques to select 62 teachers and 23 Curriculum Support Officers (CSOs) who participated in the study through questionnaire and interview. Data was analyzed using both quantitative and qualitative techniques. The study revealed that teachers hold positive perception towards the use of computer technology in English vocabulary lessons. They perceived computer technology as important in improving the quality of vocabulary teaching and learning, increasing learners’ engagement and promoting innovation in English vocabulary. The study thus recommends a need to support the positive perception of teachers through provision of regular professional development opportunities on technology use for successful use of the computer technology in teaching and learning.

Study of the stability of the biologically active compound N-[2-[4-oxo-3(4H)-quinazolinyl]propionyl]-guanidine using electrophoresis and mass spectrometry

At the Scientific Centre of Innovative Medicines of Volgograd State Medical University, a number of pyrimidine derivatives of guanidine were designed and synthesised to study them as promising inhibitors of sodium-hydrogen exchanger isoform 1 (NHE-1), which can reduce tissue damage during ischemia. N-[2-[4-oxo-3(4H)-quinazolinyl]propionyl]-guanidine (VMA-13-15) proved to be the most pharmacologically valuable compound. When preparing regulatory documentation for a new medicine, one of the quality criteria is the amount of related impurities. They can be technological impurities and degradation products of the active substance. The aim of the research was to study the stability of the biologically active compound N-[2-[4-[4-oxo-3(4H)-quinazolinyl]propionyl]-guanidine. Anticipated degradation products were determined by stress testing, using capillary electrophoresis and mass spectroscopy. The study of the molecule of VMA-13-15 and the use of computer technologies allowed us to predict possible degradation processes. Among them, the most likely to occur is the hydrolysis reaction during thermostating of the solution of the studied compound in an alkaline medium. In silico optimisation of the geometry of the studied structures was carried out by the MM+ molecular mechanics method using HyperChem 8.0.9. The final spatial optimisation of the geometry of the modelled molecules was carried out by the density functional theory method ub3lyp with 6-311G** basis sets. The resulting vibrational analysis of thermodynamic characteristics was carried out in Orca, which allowed us to obtain enthalpy and entropy values for the studied compounds. By capillary electrophoresis, the degradation products of an aqueous solution of the studied substance were analysed by stress tests. They were used to study the effect of thermal treatment on VMA-13-15 in the presence of 0.1 M hydrochloric acid solution and 0.1 M sodium hydroxide solution. We found that the alkaline environment had the greatest effect on the stability of N-[2-[4-oxo-3(4H)-quinazolinyl]propionyl]-guanidine. It was consistent with the results of the computational experiment. We studied the mass spectrum of the degradation product detected during thermostatic treatment in alkaline medium. Based on its molar mass and release time, it was confirmed that the impurity on the chromatograms of VMA-13-15 is unsubstituted quinazolin-4(3H)-one, the initial product of the synthesis