One of the most significant ways of removing chemical elements from the body is the urinary route. Thus, knowing the concentration of chemical elements in the urine, as well as the chemical composition of the diet, an attempt can be made to assess the dependence of the degree of excretion of macro- and micronutrients on the consumption of nutrients. The aim of the study was to identify the dependence of the excretion of chemical elements in urine on the nutritional intake of macro- and micronutrients using the example of first-year students of RUDN University. 75 first-year students of RUDN University, aged 20 to 50, took part in the study. The morning urine samples were taken from the subjects for analysis on chemical elements by the method of mass spectrometry with inductively coupled plasma, and their nutritional status was evaluated by frequency analysis. A positive correlation was revealed between the urinary concentration of Cr and Fe with the nutritional intake of all macronutrients, the total energy value of the diet, the consumption of cholesterol, K, Na, Mg, S, I, Se, Cu, Zn, Fe, vitamins B2, B5, B12, D. Concentration Cr in urine, in addition, was higher in women with a high consumption of Mn, and the concentration of iron was higher with a high intake of Si. Al concentrations were inversely correlated with all the same indicators, except for Mn, I, Se, Si, K, S. With an increase in total fat intake, Al concentrations in urine increased. The most universal dependences of the degree of excretion of chemical elements on nutrients were found for aluminum, chromium, and iron.