The lock down in COVID-19 affected India’s economy, health and quality of life, causing an indefinite standstill for the majority of major urban areas in India. Check out the different economic and health challenges faced by the urban populations of India and their lock down perceptions, CHD Group has conducted the Mangalore based global health organization this national evaluation survey. 604 respondents from 25 Indian states (including the Delhi and Jammu and Kashmir Union territories) were surveyed. The survey involved respondents from all the worst-hit countries, including Maharashtra, Gujarat, Delhi, Madhya Pradesh and Ra, who had confirmed COVID-19 as on 1 May 2020. According to the CHD Group’s COVID-19 Lock down National Assessment Survey, 40% of India’s urban population is living in fear of unemployment. In addition, 15% of employed respondents do not receive the same monthly income during the lock-down period. A worryingly large proportion (48 %) of respondents face difficulties in accessing essential commodities during the lock-up. 21% faced difficulties in purchasing medicines, and 18% faced difficulties in accessing healthcare facilities, even in urban centres. Inadequate access to healthcare facilities during the lockdown may lead to potential exacerbations of their pre-existing illnesses. Furthermore, access constraints to medicines and healthcare facilities were highest among respondents from the states of Maharashtra, Tamil Nadu, Delhi, Andhra Pradesh and Karnataka, which also collectively account to nearly 60% of COVID-19 cases in India. (https://www.chdefforts.org/ publications/, 2020) Based on the situation, we planned the assessment of Quality of Life of People with Epilepsy during the COVID Pandemic.