Unusual Events Research Articles

‘We don’t live in a harm reduction world, we live in a prohibition world’: tensions arising in the design of drug alerts

BackgroundDrug alerts designed for health and community workforces have potential to avert acute harms associated with unpredictable illicit drug markets, by preparing workers to respond to unusual drug-related events, and distribute information to service users. However, the design of such alerts is complicated by diverse needs of individuals, and broader socio-political contexts. Here, we discuss the tensions that arose in the process of co-designing drug alert templates with health and community workers.MethodsWe conducted five in-depth digital co-design workshops with 31 workers employed in alcohol and other drug and urgent care settings. Our approach to analysis was informed by Iterative Categorisation and reflexive thematic analysis methods.ResultsWe identified five key tensions. First, there is a need to provide comprehensive information to meet the information needs of a diverse group of workers with varying knowledge levels, while also designing alerts to be clear, concise, and relevant to the work of individuals. Second, it is important that alerts do not create ‘information overload’; however, it is also important that information should be available to those who want it. Third, alert design and dissemination must be perceived to be credible, to avoid ‘alert scepticism’; however, credibility is challenging to develop in a broader context of criminalisation, stigmatisation, and sensationalism. Fourth, alerts must be carefully designed to achieve ‘intended effects’ and avoid unintended effects, while acknowledging that it is impossible to control all potential effects. Finally, while alerts may be intended for an audience of health and community workers, people who use drugs are the end-users and must be kept front of mind in the design process.ConclusionsThe co-design process revealed complexities in designing drug alerts, particularly in the context of stigmatised illicit drug use, workforce diversity, and dissemination strategies. This study has highlighted the value of developing these important risk communication tools with their target audiences to ensure that they are relevant, useful, and impactful. The findings have informed the development of our drug alert prototypes and provide local context to complement existing best-practice risk-communications literature.

בין מלחמת "יש ברירה" לרציפות תפיסת הביטחון הישראלית: עיון מחודש בתפיסות שהובילו למלחמת לבנון הראשונה

The Israeli public largely views Israel’s invasion of Lebanon in the summer of 1982 as an unusual event, a deviation from the path that Israel had followed until then. Unlike other wars, Israel did not fight in the Lebanon War for security purposes, but for the political aims and whims of Prime Minister Menachem Begin and Defense Minister Ariel Sharon. Therefore, this war is considered a war of choice, waged by Israel when it was not under an existential threat. The claim that the Lebanon War constitutes an exceptional event in Israeli history is at the heart of this article. In order to determine whether the Lebanon War was indeed a deviation from the “right path” of the State of Israel, we examine it in light of the Israeli security doctrine that had led Israel’s decision-makers until then and that, to some extent, continues to govern them to this day. Using the security doctrine as a guide, we find that this war was not a deviation or an anomaly, but rather an application of Israeli security principles.

A focus on the last 1000 years of natural environmental changes in the tropical rainforests of West and Central Africa. Can we detect anthropogenic disturbances?

The vast tropical rainforests of West and Central Africa were impacted by marked climatic deterioration, which mainly developed between 2500 and 2000 cal yr BP. However, the incidence of human intervention in these rainforests appears all the more speculative, although this was the period when the first stages of Bantu migration occurred towards the south. On the scale of the last millennium, which has seen increasing penetration and colonization of these Bantu peoples, one can envisage a priori a more accentuated anthropogenic pressure on the forest landscape. The combined observations of the environmental processes during the last 1000 years, as preserved in sediments from lakes, swamps, flooded forests and even oceanic environments, are presented on the basis of 24 records. The dominant number of sites in the humid forest or wooded savannas recorded only processes of relatively small size and local effects influencing vegetation cover almost simultaneously around 1000 and 500 cal yr BP; nothing is comparable with the devastating effect on a very large scale of the 2600 cal yr BP forest crisis. Conversely, other sites located in more perennial forest or savanna did not reveal any discontinuity. In all the examples of sedimentary archives considered, no out-of-phase or unusual event, possibly linked to human population and its impact, was observed. However, in more recent times, in intensive iron-ore mining/smelting areas, changes in the vegetal cover could be a legacy of charcoal production impacting forest biomass. Nevertheless, despite the clear cultural and socio-political importance of iron, its role in shaping vegetation communities in the Central African forest is generally presumed to be negligible. The oceanic causes of these climatic oscillations are more widely accepted. On a larger scale, the Medieval Warm Period and Little Ice Age are climatic anomalies visible in a number of palaeoenvironmental records worldwide and date to ∼1600–1000 cal yr BP and ∼ 700–100 cal yr BP, respectively. These events are less visible or sometimes not present in some palynological records of tropical Africa, whereas reconstructions from lacustrine records in Atlantic equatorial Africa show overall reductions in lake levels and increases in pollen belonging to light-demanding and pioneer vegetation formations in relation to these two oscillations. To reply to what was more important «the potential influence of human activities on regional climate, or the vulnerability of societies to environmental variability», it appears clearly to date, that the second paradigm is most likely. However, today, the ongoing combined efffects of climate change and human impact, including the decimation of the diversity of seed dispersers necessary to regenerate the rainforests of West and Central Africa, may have irreparable and unforeseen consequences.

A Light in the Dark: Searching for Electromagnetic Counterparts to Black Hole–Black Hole Mergers in LIGO/Virgo O3 with the Zwicky Transient Facility

The accretion disks of active galactic nuclei (AGNs) are promising locations for the merger of compact objects detected by gravitational wave (GW) observatories. Embedded within a baryon-rich, high-density environment, mergers within AGNs are the only GW channel where an electromagnetic (EM) counterpart must occur (whether detectable or not). Considering AGNs with unusual flaring activity observed by the Zwicky Transient Facility (ZTF), we describe a search for candidate EM counterparts to binary black hole (BBH) mergers detected by LIGO/Virgo in O3. After removing probable false positives, we find nine candidate counterparts to BBH mergers during O3 (seven in O3a, two in O3b) with a p-value of 0.0019. Based on ZTF sky coverage, AGN geometry, and merger geometry, we expect ≈3(N BBH/83)(f AGN/0.5) potentially detectable EM counterparts from O3, where N BBH is the total number of observed BBH mergers and f AGN is the fraction originating in AGNs. Further modeling of breakout and flaring phenomena in AGN disks is required to reduce our false-positive rate. Two of the events are also associated with mergers with total masses >100 M ⊙, which is the expected rate for O3 if hierarchical (large-mass) mergers occur in the AGN channel. Candidate EM counterparts in future GW observing runs can be better constrained by coverage of the Southern sky as well as spectral monitoring of unusual AGN flaring events in LIGO/Virgo alert volumes. A future set of reliable AGN EM counterparts to BBH mergers will yield an independent means of measuring cosmic expansion (H 0) as a function of redshift.

No changes in hemostasis after COVID-19–heterologous vaccination schedule: A subanalysis of the phase 2 CombiVacS study

BackgroundSeveral cases of unusual thrombotic events and thrombocytopenia were described after vaccination with recombinant adenoviral vectors encoding the spike protein antigen of SARS-CoV-2. ObjectivesThe objective of this study was to elucidate the impact of a COVID-19 heterologous vaccination schedule, including priming with adenovirus vaccine, on hemostasis profiles. MethodsThe present study is a subanalysis of the CombiVacS clinical trial initiated in April 2021 that included adult participants previously vaccinated with a single dose of ChAdOx1-S. Between 8 and 12 weeks after vaccination, they were randomly assigned (2:1) to receive either BNT162b2 vaccine (intervention group, n = 99) or continue observation (control group, n = 50). Samples drawn before and 28 days after a vaccination with BNT162b2 were analyzed for platelet count and markers of hemostasis (D-dimer, anti-PF4 antibodies, cfDNA, PAI-1, thrombin generation, and serum capacity to activate platelets). ResultsPlatelet count from all participants after receiving BNT162b2 was within the normal range. Anti-PF4 antibodies were present in 26% and 18% of the subjects from the control and intervention groups, respectively, at day 28. In most cases, the levels of anti-PF4 antibodies were high before receiving BNT162b2. Serum from these participants did not activate platelets from healthy controls. There were no differences between the groups in PAI-1 and cfDNA plasma levels. According to the D-dimer plasma concentration, the thrombin generation test showed that none of the participants had a procoagulant profile. ConclusionOur data suggest that the heterologous vaccination against COVID-19 with ChAdOx1-S and a second dose with BNT162b2 might be safe in terms of haemostasis.

Familial imperforate hymen among three sisters of varying ages from the same mother: Case report about an unusual family event

Imperforate hymen is a rare condition, occurring in 1 in 2000 females in childhood period. However, it is not an uncommon cause of lower abdominal pain in girls. Without careful history taking and a thorough examination, the diagnosis can easily be missed. We report three cases of girls aged 8 years, 6 years and 33 months born of the same mother with imperforate hymen, who presented with varying symptoms. It should be noted that the mother also had a history of imperforate hymen. The diagnosis of imperforate hymen was made by history, physical examination and abdominopelvic ultrasound scan. All girls had a successful hymenectomy followed by a complication free recovery. No other abnormalities were diagnosed. A high index of suspicion is paramount among girls born in families that have a history of imperforate hymen to ensure timely diagnosis and management. Exhaustive physical examination at birth or during puberty is mandatory which often guides the timing of hymenectomy and prevents the complications in this category of patients.

Social representations of pregnant women about high-risk pregnancy: repercussions for prenatal care.

To analyze the Social Representations of pregnant women about high-risk pregnancy and its repercussions for prenatal care. Qualitative study, based on the procedural aspect of the Theory of Social Representations, carried out with 62 high-risk prenatal pregnant women at a High Complexity Maternity, in Belém, PA, Brazil. Data from semi-structured interviews were processed by the software Interface de R pour les Analyzes Multidimensionnelles de Textes et de Questionnaires. Four categories emerged, in which three dimensions of the Theory composing the genesis of Social Representations are considered: the affective dimension, the biological dimension and the sociocultural dimension. Affects, negative feelings, and adaptations were revealed, with high-risk pregnancy being represented as an unusual and uncomfortable event, influenced by common sense and science, communication means, and dialogues with health professionals, with family support being considered of paramount importance. and prenatal care a propitious moment for establishing bonds with the health professional, seen as essential for their adherence to the care offered.

Polarized Au(I)/Rh(I) bimetallic pairs cooperatively trigger ligand non-innocence and bond activation.

The combination of molecular metallic fragments of contrasting Lewis character offers many possibilities for cooperative bond activation and for the disclosure of unusual reactivity. Here we provide a systematic investigation on the partnership of Lewis basic Rh(I) compounds of type [(η5-L)Rh(PR3)2] (η5-L = (C5Me5)- or (C9H7)-) with highly congested Lewis acidic Au(I) species. For the cyclopentadienyl Rh(I) compounds, we demonstrate the non-innocent role of the typically robust (C5Me5)- ligand through migration of a hydride to the Rh site and provide evidence for the direct implication of the gold fragment in this unusual bimetallic ligand activation event. This process competes with the formation of dinuclear Lewis adducts defined by a dative Rh → Au bond, with selectivity being under kinetic control and tunable by modifying the stereoelectronic and chelating properties of the phosphine ligands bound to the two metals. We provide a thorough computational study on the unusual Cp* non-innocent behavior and the divergent bimetallic pathways observed. The cooperative FLP-type reactivity of all bimetallic pairs has been investigated and computationally examined for the case of N-H bond activation in ammonia.

An Unusual Skin Adverse Event after Switching from Intravenous to Subcutaneous VEDOLIZUMAB Therapy in Patients with Ulcerative Colitis

An Unusual Skin Adverse Event after Switching from Intravenous to Subcutaneous VEDOLIZUMAB Therapy in Patients with Ulcerative Colitis

Causes of death and pathogen prevalence in bottlenose dolphins Tursiops truncatus stranded in Alabama, USA, between 2015 and 2020, following the Deepwater Horizon oil spill.

Between 2010 and 2014, an unusual mortality event (UME) involving bottlenose dolphins Tursiops truncatus occurred in the northern Gulf of Mexico, associated with the Deepwater Horizon oil spill (DWHOS). Cause of death (COD) patterns in bottlenose dolphins since then have not been analyzed, and baseline prevalence data for Brucella ceti and cetacean morbillivirus, 2 pathogens previously reported in this region, are lacking. We analyzed records from bottlenose dolphins stranded in Alabama from 2015 to 2020 with necropsy and histological findings to determine COD (n = 108). This period included another UME in 2019 associated with prolonged freshwater exposure. A subset of individuals that stranded during this period were selected for molecular testing for Brucella spp. and Morbillivirus spp. Causes of death for all age classes were grouped into 6 categories, including (1) human interaction, (2) infectious disease, (3) noninfectious disease (prolonged freshwater exposure and degenerative), (4) trauma, (5) multifactorial, and (6) unknown. Two additional categories unique to perinates included fetal distress and in utero pneumonia. Human interaction was the most common primary COD (19.4%) followed closely by infectious disease (17.6%) and noninfectious disease (freshwater exposure; 13.9%). Brucella was detected in 18.4% of the 98 animals tested, but morbillivirus was not detected in any of the 66 animals tested. Brucella was detected in some moderately to severely decomposed carcasses, indicating that it may be beneficial to test a broad condition range of stranded animals. This study provides valuable information on COD in bottlenose dolphins in Alabama following the DWHOS and is the first to examine baseline prevalence of 2 common pathogens in stranded animals from this region.

UIT-ADrone: A Novel Drone Dataset for Traffic Anomaly Detection

Anomaly detection plays an increasingly important role in video surveillance and is one of the issues that has attracted various communities, such as computer vision, machine learning, and data mining in recent years. Moreover, drones equipped with cameras have quickly been deployed to a wide range of applications, starting from border security applications to street monitoring systems. However, there is a notable lack of adequate drone-based datasets available to detect unusual events in the urban traffic environment, especially in roundabouts, due to the density of interaction between road users and vehicles. To promote the development of anomalous event detection with drones in the complex traffic environment, we construct a novel large-scale drone dataset to detect anomalies involving realistic roundabouts in Vietnam, covering a large variety of anomalous events. Traffic at a total of three different roundabouts in Hochiminh city was recorded from a camera-equipped drone. The resulting dataset contains 51 videos with total data traffic of nearly 6.5 hours, captured across 206K frames with ten abnormal event types. Based on this dataset, we comprehensively evaluate the current state-of-the-art algorithms and what anomaly detection can do in drone-based video surveillance. This study presents a detailed description of the proposed UIT-ADrone dataset, along with information regarding data distribution, protocols for evaluation, baseline experimental results on our dataset and other benchmark datasets, discussions, and paves the way for future work. The dataset is available online for non-commercial research at <uri xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">https://uit-together.github.io/datasets/UIT-ADrone/</uri> .

Structural Elements and Requirements in Forming Prehospital Health Response Teams in Response to Chemical, Biological, Radiation, and Nuclear Incidents (CBRN), a Comparative Review Study.

One of the important indicators of increasing the capacity of the health system and the chances of survival of patients and injured immediately after chemical, biological, radiation and nuclear (CBRN) accidents is rapid access to medical services. Establishing prehospital health response teams is one of the main strategies to improve the capacity and ability to respond to unusual events. The aim of this study was to investigate the factors influencing the formation of rapid response teams in the field of health in response to chemical, biological, radiation and nuclear accidents (CBRN EDMRT). In this study, the comparative review method was used. The study period was from November 1, 2021 to March 2022. Forming and deploying rapid health response teams based on an extensive multi-step search and keywords in multiple databases such as PubMed, CINHAL, Blackwell, Iranmedex, SID, Cochrane Database of Systematic Reviews, Google Scholar, Scopus Also, the websites of the Ministry of Health and the responsible organizations in different countries and the proposed structure were done by international institutions and sites. After accessing the resources and documents, the process of analysis and comparison of different team structures was performed. After the initial search, the structure and required elements of their teams were extracted. According to published articles and texts, 10 teams from the International Atomic Energy Agency (IAEA), the US Centers for Disease Control and Prevention (CDC), the US Department of Homeland Security, and the North Atlantic Treaty Organization (NATO), Australia, the British Public Health Organization, and the Japanese Red Cross were compared. Team requirements, population distribution, type of accident, level of team activity and training, equipment required by the team after the accident, according to which, each country/organization should consider the above factors to design and establish the structure of CBRN EDMRT to take. A study should be conducted to design a comprehensive and evidence-based structure.

The roles and regulation of Yes-associated protein 1 in stem cells

Yes-associated protein 1 (YAP1) is a downstream effector of the Hippo signaling pathway, and it is involved in tumorigenesis, tissue repair, growth, and development. In this review, the biological roles and the mechanisms of YAP1 in mediating stem cell fate decisions are discussed, including cell proliferation, differentiation, and apoptosis. In general, YAP1 promotes the proliferation and differentiation of stem cells, including embryonic stem cells and adult stem cells. It inhibits apoptosis by binding to the transcription factors, e.g., transcriptional enhanced associate domain (TEAD), Smad, runt-related transcription factor 1/2, p73, p63, and Erb84, to maintain tissue homeostasis. The translocalization of YAP1 in cellular nuclei and the phosphorylation in the cytoplasm work as important and unusual events for the activation of YAP1. Moreover, YAP1 serves as the crosstalk for the Hippo pathway and other signaling pathways, including the Wnt and Notch pathways. It is highlighted in this review that YAP1 is an essential regulator for stem cells that have significant applications in regenerative medicine and reproductive medicine.

Type II Myocardial Infarction and Stress Cardiomyopathy Secondary to Inhaled Foreign Body (Garden Pea)

Abstract A foreign body aspiration is an unusual event in the adult population, outside of known risk factors such as neurological disease. It typically presents as "cough (67%), dyspnoea (28%), chest pain, cyanosis, stridor or obstruction" and "wheezing (12.7%) and haemoptysis (23.3%)". The authors present the case of inhaled foreign body (pea) in a 69-year-old lady, without underlying risk factors for aspiration. On admission, she was tachypnoeic and unable to speak in full sentences. Her Computerised tomography (CT) scan showed ground-glass changes and potentially superimposed infective changes. Whilst awaiting transfer for bronchoscopy, she developed severe respiratory distress with cardiovascular compromise (new left bundle branch block (LBBB), tachycardia and hypertension). She was intubated in extremis and commenced on noradrenaline. Her angiogram showed mild non-obstructive disease, and she was diagnosed with a type two myocardial infarction and stress-induced cardiomyopathy. The pea was later removed on intensive care via flexible-bronchoscopy. Learning points include the potential for patients with a foreign body to acutely deteriorate, hence the need for urgent bronchoscopic removal and the potential to develop myocardial ischaemia secondary to acute respiratory distress.

Histopatología de juveniles cultivados de Totoaba macdonaldi asociados con aislamientos bacterianos identificados molecularmente como Vibrio spp. durante un evento de aumento de temperatura

Totoaba macdonaldi is an endangered species of croaker endemic to the Gulf of California, Mexico. This species has been cultured for the repopulation of wild stocks and commercialization at the Wildlife Management and Conservation Unit for the culture of T. macdonaldi at the Universidad Autónoma de Baja California, Mexico. A mortality episode was observed in 50 day-old juveniles, that coincided with an increase of temperature from 16 to 25.5˚C that affected the aquaculture facility. Histopathological and bacteriological analysis of survivor fishes were conducted to investigate the possible causes of mortality. Gill damage including severe congestion in gill filaments, necrosis, and epithelial dissociation of lamellae were observed. Moreover, epidermal, hypodermic necrosis, as well as diffuse bacterial colonization of the dermis was detected. Severe congestion and hemolysis were detected in the heart’s atrium and hepatic portal vessels. From the skin lesions, eight colonies of bacteria were isolated, these corresponded to four species of genus Vibrio, tentatively identified by partial sequence of the 16S rRNA gene as Vibrio harveyi, V. rotiferianus, V. brasilensis and V. shilonii. From them, V. harveyi corresponded to 4 of the 8 isolates and was found in all moribund fishes. Characteristics of the tissue alterations related with these opportunistic Vibrio spp. suggest an acute mortality event favoured by a temperature increase. This is the first record of the histopathology of T. macdonaldi juveniles that suffered an unusual mortality event under an increase of temperature in cultured conditions associated with Vibrio spp.

Strengthened Impacts of Indian Ocean Dipole on the Yangtze Precipitation Contribute to the Extreme Rainfall of 2020 Meiyu Season

AbstractIn June‐July 2020, the Middle and Lower Yangtze River Region (MLYR) encountered the most severe precipitation event over the past 60 years. The Indian Ocean Dipole (IOD) in the previous autumn of the unusual precipitation event was the main contributing factor. Nonetheless, not every strong IOD event could bring anomalously high precipitation in the MLYR. This study showed significantly enhanced influence of IOD on East Asia climate since 2000. The IOD's effect on MLYR summer precipitation has strengthened significantly with the correlation coefficient up to 0.55 during 2000–2020. The northward movement of East Asia–Pacific pattern associated with IOD since 2000 (as compared with before) was primarily responsible for the enhanced effect. Since 2000, the MLYR has been controlled by a deep baroclinic instability system with anomalous low pressure in the lower troposphere and anomalous high pressure (completely different from before). Furthermore, the western Pacific subtropical high shifted northward and westerly jets were significantly enhanced with eastward expansion. All of these patterns contributed to the water vapor convergence and precipitation generation in the MLYR, which was not the case in the past. The record‐breaking IOD in 2019 autumn and the enhanced IOD's climatic effect in 2000–2020 contribute to the extreme Meiyu in 2020 jointly. The significant change in the influence of IOD and the enhanced climate effect of IOD highlight exciting new avenues for improving climate predictions in the MLYR.

Analisis Psikologi Tokoh Utama dalam Novel Bidadari Karya Pipiet Senja

Novels include many problems of everyday life. This is also what is in the novel Bidadari by Pipiet Senja. The novel shows the unusual events of a woman, namely from the psychological side of the main character played by Soli. The Bidadari novel shows the psychology of the main character about physiology, security, love and belonging, self-esteem, and self-actualization. This study aims to describe the psychology of the main character in the novel Bidadari by Pipiet Senja. This type of research is a qualitative research. The results showed that the psychology of the main character found was as follows: first, there were 16 physiological needs. Second, the need for security is 10 data. Third, the need for love and taste has as many as 42 data. Fourth, the need for self-esteem as much as 6 data. Fifth, the need for self-actualization as many as 8 data. Based on the results of the study, it can be concluded that the most dominant psychology of the main character found is the need for love and belonging. The least psychology of the main character is the need for self-esteem.

Addressing the Silent Spread of Monkeypox Disease with Advanced Analytical Tools.

Monkeypox disease is caused by a virus which belongs to the orthopoxvirus genus of the poxviridae family. This disease has recently spread out to several non-endemic countries. While some cases have been linked to travel from endemic regions, more recent infections are thought to have spread in the community without any travel links, raising the risks of a wider outbreak. This state of public health represents a highly unusual event which requires urgent surveillance. In this context, the opportunities and technological challenges of current bio/chemical sensors, nanomaterials, nanomaterial characterization instruments, and artificially intelligent biosystems collectively called "advanced analytical tools" are reviewed here, which will allow early detection, characterization, and inhibition of the monkeypox virus (MPXV) in the community and limit its expansion from endemic to pandemic. A summary of background information is also provided from biological and epidemiological perspective of monkeypox to support the scientific case for its holistic management using advanced analytical tools.

Environmental Monitoring for Arctic Resiliency and Sustainability: An Integrated Approach with Topic Modeling and Network Analysis

The Arctic environment is experiencing profound and rapid changes that will have far-reaching implications for resilient and sustainable development at the local and global levels. To achieve sustainable Arctic futures, it is critical to equip policymakers and global and regional stake- and rights-holders with knowledge and data regarding the ongoing changes in the Arctic environment. Community monitoring is an important source of environmental data in the Arctic but this research argues that community-generated data are under-utilized in the literature. A key challenge to leveraging community-based Arctic environmental monitoring is that it often takes the form of large, unstructured data consisting of field documents, media reports, and transcripts of oral histories. In this study, we integrated two computational approaches—topic modeling and network analysis—to identify environmental changes and their implications for resilience and sustainability in the Arctic. Using data from community monitoring reports of unusual environmental events in the Arctic that span a decade, we identified clusters of environmental challenges: permafrost thawing, infrastructure degradation, animal populations, and fluctuations in energy supply, among others. Leveraging visualization and analytical techniques from network science, we further identified the evolution of environmental challenges over time and contributing factors to the interconnections between these challenges. The study concludes by discussing practical and methodological contributions to Arctic resiliency and sustainability.

195. Attack of the drones: case report - nasal tip avulsion and replantation guidelines

Unmanned aircrafts systems, commonly known as “drones”, have risen in popularity in the last decade. We report a case where a young adult was brought to our A&E after suffering a nasal tip amputation due to the blades of a remote controlled drone.Generally the traumatic amputation of the nose is an unusual event that requires a prompt treatment and its management can be challenging and complex.The literature reports several cases of successful nasal replantation as a simple composite graft or with microsurgical revascularisation.