The two cases here reported present some unusual features. While they differ widely from each other in the fundamental conditions present, they have in common unusual calcareous deposits occurring in the epiphyses of some of the long bones in one patient, and in the skin and subcutaneous tissues in the other. REPORT OF CASES Case1.—A boy, aged 5 weeks, admitted to the Hospital for Sick Children, Nov. 25, 1922, weighing 4 pounds and 11 ounces (2,126 gm.), was markedly emaciated and had a flexion deformity involving almost all of the joints of the body. The arms could not be elevated above the shoulders, the forearms could not be fully extended and the fingers were flexed so that, with the exception of the index fingers, they touched the palm. A slight permanent kyphosis was present. The hips, knees and ankles were also involved so that extension beyond an angle of
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