Abstract Machine Learning (ML), a sub-field of Artificial Intelligence (AI), is profoundly reshaping various aspects of human life. Its application in engineering systems promises to address long-standing challenges, although it also introduces new questions. While the potential of ML is undeniable, integrating existing ML methods into Computer-Aided Design and Manufacturing (CAD/CAM) presents distinctive challenges. These challenges encompass representation, adaptation, and the development of novel ML techniques to enhance CAD/CAM systems for diverse design and manufacturing solutions. This special issue aims to explore and resolve issues related to effective engineering model representation for ML, the integration of neural networks and deep generative models into CAD/CAM, mathematical frameworks combining ML with CAD/CAM in geometry and topology, data interpretation, and physics-based learning. The issue features ten papers that delve into various topics, including material prediction for assemblies, robotics mechanism design, multi-modal ML in engineering design, data-driven component segmentation in engineering drawings, evaluating assembly-part semantic knowledge in language models, three-dimensional slice reconstruction from high-resolution 2D images, physics-informed neural networks to expedite thermal simulations in additive manufacturing, transfer learning for defect detection in steel strips, AI-aided hull form design for energy-efficient unmanned underwater vehicles, and real-time high-precision calibration of quadruped robots using machine vision and artificial neural networks. Below, we provide concise summaries of each of the ten papers published in this special issue.
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