Distributed switched large-scale systems are composed by dynamically coupled subsystems, in which interactions among subsystems vary over time according a switching signal. This paper presents a distributed robust switched model-based predictive control (DSwMPC) to control such systems. The proposed method guarantees stabilising the origin of the whole closed-loop system and ensures the constraints satisfaction in the presence of an unknown switching signal. In the distributed model-based predictive control (DMPC) used in this work, by considering the interactions among subsystems as an additive disturbance, the effect of the switch is reflected on the dynamic equation, local, and consistency constraint sets of the nominal subsystems. To compensate the effect of switching signal which creates a time-varying network topology, a robust tube-based switched model-based predictive control (RSwMPC) with switch–robust control invariant set as the target set robust to unknown mode switching is used as local controller. The scheme performance is assessed using three typical examples. The simulation results show that the input and state constraints are satisfied by the proposed DSwMPC at all times. They also validate that the closed-loop system converges to the origin. Also, a comparison of the DSwMPC with a centralised SwMPC (CSwMPC) and a decentralised SwMPC (DeSwMPC) are performed.