Purpose This study examined the effects of nursing professionalism, academic failure tolerance and social self-efficacy on college life satisfaction among nursing students. Methods Data were collected between September 1 and October 16, 2015 via a self-reported questionnaire from 170 nursing students using convenient sampling methods. The survey included questions about nursing professionalism, academic failure tolerance, social self-efficacy, and college life satisfaction. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, and hierarchical multiple regression with IBM SPSS/WIN 20.0. Results Establishment vision about nursing science (β=.27, p=.006), academic failure tolerance (β=.17, p=.031) and social self-efficacy (β=.19, p=.012) of nursing students were identified as significant predictors of college life satisfaction, after adjusting for establishment vision about nursing science and satisfaction in nursing science. This model explained 21.0% of the college life satisfaction in nursing students (F=6.38, p<.001). Conclusion These results suggest that academic failure tolerance and social self-efficacy were significant factors influencing the college life satisfaction of nursing students. Also, as a strategy for improving the college life satisfaction of nursing students, it is necessary to develop programs that can help to establish apparent vision and to improve satisfaction in nursing science. Keywords: Nursing, Personal satisfaction, Professionalism, Self-efficacy 주ìì´: ê°í¸, ê°ì¸ì ë§ì¡±ë, ì 문ì§ê´, ì기í¨ë¥ê°