Guangzhou University Research Articles

Protocol for the derivation and external validation of a 30-day postoperative pulmonary complications (PPCs) risk prediction model for elderly patients undergoing thoracic surgery: a cohort study in southern China

IntroductionPostoperative pulmonary complications (PPCs) occur after up to 60% of non-cardiac thoracic surgery (NCTS), especially for multimorbid elderly patients. Nevertheless, current risk prediction models for PPCs have major limitations regarding...

A Study on Influencing Factors towards Online Financial Management Ability among College Students in Guangzhou

With today's rapid expansion of online financial services, college students' online financial management awareness is rapidly improving, as citizens' financial management awareness gradually improves. The purpose of this study is to examine network financial management ability, with the goal of investigating the financial management ability development of college students in the Internet field of vision. College students' network financial management capabilities should include network financial management concepts, network financial ethics, network financial management knowledge, and network financial execution ability, based on a comprehensive perspective of financial management, finance, pedagogy, statistics, and other disciplines, after consulting relevant materials and drawing on the opinions of relevant scholars. And a financial risk control system for the network. Based on the theories used are Cognitive Learning Theory (CLT), perceived risk, financial management theory, Quality Development Theory and Platform Economic Theory, the author conducted a questionnaire survey in certain colleges and universities in Guangzhou, Guangdong Province. The questionnaire's survey objects, as well as the scores for each question, are sorted and examined. Using data analysis shows the current state of network financial management principles, network financial management ethics, network financial management knowledge, network financial execution power, and network financial risk control among college students.

Academic Adaptation of Young Returnee Teachers from the Perspective of Social Capital: A Case Study of Humanities and Social Sciences in Universities in Guangzhou

Academic Adaptation of Young Returnee Teachers from the Perspective of Social Capital: A Case Study of Humanities and Social Sciences in Universities in Guangzhou

Experimental Investigation of Indoor Thermal Comfort under Different Heating Conditions in Winter

Owing to historical reasons, only a few locations in the Guangdong province use heating to enhance interior thermal conditions. With the variation in climate and increase in people’s lifestyle requirements, winter heating has become increasingly necessary. However, a literature review revealed that only a few studies have investigated the heating requirements during winter in the Guangdong province. In this study, we compared the thermal comfort of radiant floor heating with wall-mounted air conditioner heating. A Guangzhou University climate chamber was used in several investigations. The findings revealed that the thermal neutral temperatures of radiant heating and air conditioner heating were 22.0 °C and 23.0 °C, respectively, about 1 °C variation in temperature. Additionally, in the research on thermal reactions and local skin temperature measurements, the impact of local thermal discomfort on the overall thermal experience was also considered. The findings showed a direct relationship between the local thermal discomfort caused by radiant heating and general thermal sensation. Thermal sensation of the subjects mainly originated from the lower extremities and was significantly affected by Va (air velocity). The relationship between the local thermal discomfort of convective heating and general thermal sensation was weak and mainly caused by the uneven thermal environment. Thus, in south China, for lowering energy usage, radiant floor heating should be used to create an improved indoor thermal environment in winter.

Preface

The 2022 International Conference on Power System and Energy Technology (ICPSET 2022) was successfully held in Guangzhou, China on August 12-14, 2022. ICPSET 2022 provided a learning and exchange platform for experts, scholars and engineering technicians in related fields to share scientific research achievements, explore cutting-edge technologies and expand research ideas, so as to promote the development of relevant fields.In the conference, we had the honor of having invited both Prof. Fushuan Wen from Zhejiang University, China and Prof. Li Niu from Guangzhou University, China to serve as our Conference General Chairs. The conference covered keynote speeches and oral presentations, attracting 90 individuals and institutions worldwide. Primarily, keynote speakers were each allocated 30-45 minutes to hold their speeches. Then in the oral presentations, the excellent papers we had selected were presented by their authors by turns.We were delighted and honored to invite two prominent professors as keynote speakers to deliver their speeches. For a start, Assoc. Prof. Cheng Li from Changchun Institute of Technology, China performed a thought-provoking speech: Research on Operating State Sensing Technology of Insulators in Transmission and Distribution Lines Based on Linear Variable Spectroscopy. The study used microwave plasma-assisted pulse sputtering to prepare high linearity graded spectroscopic filters, developed a multi-channel contamination collection device with resistance to strong electric field interference, and changed the traditional narrow wavelength range single target detection method through hyperspectral spectroscopy technology of graded filter films, realizing the detection of electrified pollution of the insulation part of power equipment and the troubleshooting of hidden troubles. And then, Assoc. Prof. Bernard Saw Lip Huat from Universiti Tunku Abdul Rahman made a report on Aluminum-air Battery: A Green Technology for Sustainable Power Generation Via Circular Economy Approach. In this presentation, the architecture of the aluminum-air battery, factors affecting the aluminum-air battery performance, and challenges of the aluminum-air battery were presented. The wonderful speeches of each keynote speaker had triggered heated discussion. Besides, every participant praised this conference for disseminating useful and insightful knowledge.The proceedings of ICPSET 2022 are a compilation of the accepted papers and represent an interesting outcome of the conference. These papers feature but are not limited to the following topics: Distribution Automation, Power System Technology, Renewable Energy, Energy Efficiency, etc. All the papers have been checked through rigorous review and processes to meet the requirements of publication.We would like to express our sincere appreciation to all of those who supported ICPSET 2022. In particular, we would like to thank the Journal of Physics: Conference Series, for the endeavor of all the colleagues in publishing this paper volume. The help and contribution of each individual and institution was instrumental in the success of the conference and with the strong support, we are sure ICPSET 20222 has been beneficial to all the attendees.The Committee of ICPSET 20222List of Committee member is available in this pdf.

A bibliometrics visualization analysis and hotspots prediction for natural product on osteoporosis research from 2000 to 2021

• The bibliometrix package, VOSviewer and CiteSpace software are used to make a intuitive visualization analysis of natural product in osteoporosis research from 2000 to 2021 for the first time. • This study reveals the current application status of natural medicines in osteoporosis research and explore potential research hotspots, and guide future research directions. • The study makes suggestions and prospects on the development trend of natural product in osteoporosis research, which can help researchers to open up new directions for future research. The purpose of this study was to explore the application status of natural products in osteoporosis research and explore its research hotspots and future research directions by analyzing the literature in the field of natural products therapy for osteoporosis from 2000 to 2021. Publications on natural products in osteoporosis research were extracted from the Web of Science core collection database. Bibliometrics package in R language, VOSviewer and CiteSpace software were used for visualization analysis. From 2000 to 2021, the number of articles on natural products in osteoporosis research was 1596, and the total number of articles increased rapidly. China was the driving force in this field, and the top-contributing institution was Guangzhou University of Chinese Medicine. Most publications were published in the Journal of Ethnopharmacology . While J.K. Xu and Y. Zhang were the most cited and co-cited author. Countries, research institutions and authors in different regions cooperate closely. The hot topics included osteoporosis, differentiation, expression, in vitro , cell, osteogenesis and osteogenesis were the research frontiers in recent years. This study conducted a bibliometric visualization analysis on the research status, research hotspots and development trend of natural products in osteoporosis for the first time. In addition, this paper also puts forward suggestions and prospects for the future development of this field, which will help researchers to open up new directions for future research in this field.

Biases in student evaluations of teaching: An exploratory analysis to a Chinese case study

ABSTRACT This paper examines factors influencing on student evaluations of teaching (SET) with consideration of disciplinary variations. Data were obtained from a university in Guangzhou of China and consisted of 1443 undergraduate course ratings collected from 19 schools over two semesters. The students and courses are classified into hard and soft disciplinary groupings and divided into four sub-groups for further comparison. The result of the ANOVA test showed significant difference in the mean SET scores across four subgroups; and results of linear models reflect students who major in hard discipline tend to give higher SET scores regardless of the course’s feature. In addition, there was also evidence of possible biases in the ratings according to the features of teachers, students and courses. Overall, the disciplinary differences would need to be considered when decisions are being made on the basis of the SET scores, especially for cross-school evaluation.

Health as expanding consciousness: Change of psychological situation in nursing students.

This study aims to explore the mind of Chinese nursing students transitioning to online education in the pandemic using health as expanding consciousness (HEC) as methodology. A qualitative, descriptive study based on interviews. This qualitative study was conducted from September to November 2021 by students in the Guangzhou university of Chinese medicine. Thirteen participants were recruited using purposive sampling. A questionnaire containing two sections with demographic information, the General Self-Efficacy Scale (GSES) and the Connor-Davidson resilience scale (CD-RISC)-10 was collected to explore the health of participants. A total of 13 participants were enrolled in the study (69% female). Students ranged in age between 19 and 24 years and the mean age was 22 years. All students lived with their families. Five participants (38%) had a master's degree in nursing, three (23%) were in fourth year of college, four (30%) were in third year of college and one (7%) was in their second year of college respectively. More than half of the participants had high levels of mental toughness and self-efficacy. Four generic categories were identified form a unitary-transformative paradigm perspective. The respondents reported three health pattern phases: Curriculum Transformation, Curriculum adaptation and Curriculum expansion. This research backs up Newman's hypothesis, and supports the theoretical framework. HEC explains well the psychology of nursing students during the epidemic. More research is needed in the future to develop comprehensive, targeted emotional regulation therapies for nursing students.

Associations of emotional/behavioral problems with accelerometer-measured sedentary behavior, physical activity and step counts in children with autism spectrum disorder.

BackgroundThe evidence for associations of emotional/behavioral status with sedentary behavior (SB), physical activity (PA) and step counts is scarce in children with autism spectrum disorder (ASD). Also, ASD-related deficiencies may affect actual levels of PA. We aimed to describe accelerometer-measured SB, PA and step counts in children with ASD, and to examine the associations of emotional/behavioral problems with SB, PA and step counts after assessing associations between accelerometer-measured SB, PA and step counts and ASD-related deficiencies.MethodsA total of 93 ASD children, aged 6–9 years, were recruited from the Center for Child and Adolescent Psychology and Behavioral Development of Sun Yat-sen University in Guangzhou, China. Participants wore an accelerometer for seven consecutive days. Of the original 93, 78 participants' accelerometer-measured valid PA were obtained, and the data were shown as time spent in SB, light, moderate, moderate-to-vigorous and vigorous PA, and step counts. Participants' emotional/behavioral problems were assessed via the Strengths and Difficulties Questionnaire (SDQ), and anxiety symptoms were evaluated by the Screen for Child Anxiety Related Emotional Disorders (SCARED). ASD-associated deficiencies include restricted repetitive behaviors (Repetitive Behavior Scale-Revised), poor social competence (Social Responsiveness Scale Second Edition) and motor development restrictions (Developmental Coordination Disorder Questionnaire).ResultsOf the 78 participants, daily vigorous PA (VPA) and moderate-to-vigorous PA (MVPA) averaged 15.62 and 51.95 min, respectively. After adjustment for covariates, SDQ emotional symptoms (β = −0.060, p = 0.028) were inversely associated with the average daily minutes in VPA. Meanwhile, SDQ emotional symptoms (β = −0.033, p = 0.016) were inversely associated with the average daily MVPA minutes in the crude model. After adjustment for covariates, SCARED somatic/panic (β = −0.007, p = 0.040) and generalized anxiety (β = −0.025, p = 0.014) were negatively associated with the average daily VPA minutes; SCARED total anxiety (β = −0.006, p = 0.029) was conversely associated with daily MVPA duration. After adjustment for covariates, no significant associations between accelerometer-measured SB, PA and step counts and ASD-related deficiencies were found (p > 0.05).ConclusionsAccelerometer-measured SB, PA and step counts showed no associations with ASD-related deficiencies. On this basis, we further found that the emotional symptoms were inversely associated with VPA and MVPA. These results emphasize the importance of VPA and MVPA in children with ASD. The longitudinally investigations on the directionality of these associations between emotional symptoms with VPA and MVPA are needed in the future.

Synthesis of Mn(OH)(OCH3) as a Novel Precursor for 2D MnS‐Based Lithium‐ and Sodium‐Ion Battery Anode Materials

AbstractInvited for this issue's Front Cover is the group of Professor Feng Peng from School of Chemistry and Chemical Engineering, Guangzhou University (China). The cover picture illustrates 2D α‐MnS‐based anode materials for lithium/sodium‐ion batteries. The characteristic 2D porous structure of α‐MnS together with conductive carbon shells endow N, S co‐doped carbon coated α‐MnS composite with great Li‐/Na‐ion storage performance. Read the full text of the Research Article at 10.1002/celc.202200738.

Research status, hotspots and trends of acupuncture and moxibustion in the treatment of Alzheimer's disease: A bibliometric analysis.

Background:Acupuncture and moxibustion (AM) are utilized to treat Alzheimer’s disease (AD). However, no bibliometric analysis has explored this issue. Thus, this study investigated the status, hotspots and trends of AM in the treatment of AD.Methods:CiteSpace and VOSviewer softwares were used to analyze the literature on the AM for AD in the Web of Science Core Collection database. We analyzed the data of countries/regions, institutions, journals, authors, keywords, and cited references.Results:After removing duplicates, 193 articles were retrieved. The number of publications on this topic has increased gradually. The most productive and collaborative country was China (143 documents), followed by South Korea (19). The top 3 active academic institutions were Beijing University of Chinese Medicine, Capital Medicine University, and Guangzhou University of Chinese Medicine. The most productive journal was Evidence-based Complementary and Alternative Medicine (13 documents), followed by the Frontiers in Aging Neuroscience (10), Medicine (10), and Neural Regeneration Research (10). The top 3 co-cited journals were Evidence-based Complementary and Alternative Medicine (156 citations), Acupuncture Electro-therapeutics Research (152), and Acupuncture in Medicine (146). The research hotspots in this domain are dementia, memory, hippocampus, mouse models, and Parkinson’s disease. Major frontiers are comparing the therapeutic effects of acupuncture and donepezil and electroacupuncture at different frequencies in this field.Conclusion:This bibliometric study identified relevant hotspots and trends in research on AM in the treatment of AD, which can provide researchers with key information in this domain and help further explore new research directions.

Optical Monitoring and Variability Analyses of the FSRQ 3C 454.3

Based on the database monitored by the 1.26 m National Astronomical Observatory–Guangzhou University Infrared/Optical Telescope, we studied the optical variabilities of FSRQ 3C454.3. The monitoring period was from 2016 October 17 to 2018 December 14, and there were 6701 observations covering the g, r, and i bands (2196 at the g band, 2214 at the r band, and 2291 at the i band). (1) The maximum variabilities were Δm g = 2.806 ± 0.124 mag at the g band; Δm r = 2.365 ± 0.160 mag at the r band; and Δm i = 3.126 ± 0.070 mag at the i band. (2) Among the gri intraday lightcurves, there are 172 portions of the data sets showing intraday variability (IDV). The distributions of IDV timescales (ΔT) can be profiled by a three-order Gaussian function, with the center values ΔT 1 = 17.18 minutes, ΔT 2 = 34.91 minutes, and ΔT 3 = 68.92 minutes. These results imply that the origin of IDVs is very complicated. (3) Based on the IDV timescales, we obtained the emission size R ≤ 7.17 × 1015 cm, fixed the broad-line region and modeled the spectral energy distributions. (4) We used the Jurkevich method, red-noise fitting, and the weighted wavelet Z-transform to analyze the long-term variabilities and obtained indications of a possible period of P = 2.92 ± 0.85 yr, and used the binary black hole system to explain this period. Based on the long-term period, we can estimate the time until merger of the binary black hole, t merge = 6.69 × 103 yr, and the luminosity of gravitational waves, L G = 1.56 × 1048 erg s−1.

Translation and evaluation of the simplified Chinese version of the rating form of IBD patient concerns

BackgroundInflammatory bowel disease (IBD) has become a global public health problem. The prevalence of IBD in China increased annually in past two decades.MethodsThis study was to translate and validate the rating form of IBD patients' concerns (RFIPC), and to describe disease-related worries and concerns of patients with IBD. The simplified Chinese version of the RFIPC was developed according to translation and back-translation procedure. Patients with IBD were consecutively enrolled from the First Affiliated Hospital of Guangzhou University of Chinese Medicine. The participants were assessed using the RFIPC and the Short Inflammatory Bowel Disease Questionnaire (SIBDQ). Internal consistency, test–retest reliability, measurement error, confirmatory factor analysis (CFA) and correlation of the RFIPC with the SIBDQ were performed to evaluate the psychometric characteristics of the RFIPC.ResultsA total of 116 patients with IBD, 73 with ulcerative colitis (UC) and 43 with Crohn’s disease (CD), were enrolled in this study. Thirty-seven of them recompleted the questionnaires for the second time between 7 and 14 days after the first interview. The results of CFA indicated the original structure of the RFIPC was reasonable. Cronbach's alpha value of the RFIPC were 0.97. The intraclass correlation coefficients of four domains ranged from 0.85 to 0.92. The standard error of measurement was 7.10. The correlation coefficients between total score of the RFIPC and the SIBDQ score ranged from − 0.54 to − 0.70. Median total score of the RFIPC was 39.4 (IQR 24.0–59.3). Patients with severe symptoms reported higher scores of the RFIPC. The uncertain nature of disease, having surgery, having an ostomy bag, developing cancer, feeling out of control, being a burden on others and financial difficulties were highest concerns of patients with IBD. Comparing with patients with UC, patients with CD had more concerns of the ability to have children and being treated as different (P < 0.05).ConclusionsThe simplified Chinese version of RFIPC is a valid and reliable tool. It could be used for assessing disease-related worries and concerns of patients with IBD in China. Specific concerns of patients with UC and CD are different, therefore, health workers should consider the specific needs of UC and CD patients.

Optimal Sprinkler Application Rate of Water–Fertilizer Integration Machines Based on Radial Basis Function Neural Network

The application rate for sprinkler irrigation of water–fertilizer integration machines is an important technical parameter for efficient operation. If the value is too large, the equipment will produce runoff; if it is too small, the equipment will run too long and waste energy. Therefore, it is necessary to provide a feasible scientific and theoretical basis for developing a reasonable application rate. In this study, a mathematical model of soil infiltration for sprinkler irrigation with water and fertilizer integration machines was developed. Soil water accumulation time for different soil’s initial water content, bulk density, sprinkler application rate and soil texture were derived by the finite element method, and these data were used as a training database for the neural network. To make the neural network convenient for predicting the optimal application rate of sprinkler irrigation (the maximum application rate of sprinkler irrigation without runoff) in practice, the time of waterlogging, was multiplied by the optimal application rate of sprinkler irrigation to obtain the total irrigation volume. The optimal application rate of the sprinkler irrigation prediction model of radial basis function (RBF) neural network was constructed with total irrigation water, soil bulk density, initial water content and soil texture as inputs and compared with BP neural network and generalized regression neural network. The highest prediction accuracy of RBF neural network was obtained, and its average relative error was 0.11. To verify the accuracy of the RBF neural network application rate of sprinkler irrigation prediction model in real life, a sprinkler experiment was conducted in the laboratory of Guangzhou University, and the collected soil and lawn of Guangzhou University were used to simulate the actual environment. The results showed that the relative error between the RBF neural network prediction results and the actual values was generally around 10%, while for a total irrigation volume of 58 mm, the optimal application rate of sprinkler irrigation calculated with the model was 42 (mm/h), which can save 70% of irrigation time compared to the case of using the stable infiltration rate of soil as the application rate of sprinkler irrigation without water and fertilizer. Water and fertilizer losses were not observed. This indicates that the model proposed in this study is of practical value in determining the optimum application rate of sprinkler irrigation for water–fertilizer integration machines.

Metagenomics-based systematic analysis reveals that gut microbiota Gd-IgA1-associated enzymes may play a key role in IgA nephropathy.

Background: IgA nephropathy (IgAN) is the most common type of glomerulonephritis in Asia. Its pathogenesis involves higher expression of galactose-deficient IgA1 (Gd-IgA1) and dysregulated intestinal mucosal immunity. The objective of this study was to explore whether specific gut microbiota and associated enzymes affect Gd-IgA1 in IgAN. Methods: This study carried out shotgun metagenomic sequencing with Illumina on fecal samples collected from 20 IgAN patients (IgAN group) and 20 healthy controls (HCs group) who were recruited from January 2016 to December 2018 at the Second Clinical College of Guangzhou University of Chinese Medicine. Differences analysis in gut microbiota was performed to determine the overall microbiota composition, the representative enterotypes, and the microbiota abundance. Correlations between gut microbiota and clinical indicators were assessed by Spearman’s analysis. Moreover, the functional prediction of microbial communities and the quantitative calculation of enzymes encoded by microbiome were performed using the MetaCyc pathway and the bioBakery three platform, respectively. Results: Bacteroides plebeius and Bacteroides vulgatus levels were higher, while Prevotella copri and Alistipes putredinis levels were lower in the IgAN group compared to HCs group. Enterotype I characterized by Bacteroides was closely related to the IgAN patients. Moreover, Bacteroides fragilis, Flavonifractor plautii and Ruminococcus gnavus were characteristic bacteria enriched in IgAN patients. Spearman’s correlation analysis found that Eggerthella lenta and Ruminococcus bromii were positively correlated with urine protein-creatinine ratio, while Ruminococcus gnavus showed a direct association with red blood cells in urine, and Bacteroides vulgatus and Ruminococcus gnavus were positively correlated with eGFR. These results indicated that intestinal dysbacteriosis occurred in IgAN patients and was associated with clinical and biochemical features. In addition, MetaCyc pathway analysis predicted microbiota-related metabolic pathways, including the biosynthesis of amino acids and glycans, were associated with the IgAN group. Microbial enzymes analysis highlighted that Gd-IgA1-associated α-galactosidase and α-N-acetyl-galactosaminidase secreted by Flavonifractor plautii were enriched in IgAN patients. Conclusion: These findings suggested that α-galactosidase and α-N-acetyl-galactosaminidase secreted by Flavonifractor plautii might be related to the production of Gd-IgA1, indicating that enzymes originated from abnormal intestinal microbiota may contribute to the production of Gd-IgA1 and play an important role in the pathogenesis of IgAN.

The risk factors of neuropathic pain in neuromyelitis optica spectrum disorder: a retrospective case-cohort study

BackgroundNeuropathic pain is a common complication in neuromyelitis optica spectrum disorder (NMOSD), which seriously affects the quality of life of NMOSD patients, with no satisfactory treatment. And risk factors of neuropathic pain are still uncertain.ObjectiveTo investigate the risk factors of neuropathic pain in a NMOSD cohort.Materials and methodsOur study was a retrospective case-cohort study, the patients diagnosed with NMOSD in the Department of Neurology from the Second Affiliated Hospital of Guangzhou University of Chinese Medicine from January 2011 to October 2021 were screened. Inclusion criteria were: (1) patients diagnosed as NMOSD according to the International Panel for NMO Diagnosis (IPND) criteria, (2) the aquaporin-4 immunoglobulin G antibodies (AQP4-IgG) test was performed. Patients without AQP4-IgG antibody were excluded. Clinical data, including sex, age of the first onset, symptoms of the first episode including neuropathic pain and attack types, localization of lesions of the first episode on Magnetic Resonance Imaging (MRI), Extended disability status Scale (EDSS) of the first onset, treatment of immunosuppression in the first acute phase, disease modifying therapy (DMT), treatment of neuropathic pain and APQ4-IgG status were collected from the hospital system database. Neuropathic pain was defined according to the International Association for the Study of Pain criteria and was described as “pain arising as a direct consequence of a lesion or disease affecting the somatosensory system”.ResultsOne hundred nineteen patients were screened and finally 86 patients fulfilling the inclusion and exclusion criteria were enrolled in our study. The prevalence of neuropathic pain in patients with NMOSD was 43.0%. Univariate analysis showed that the factors associated with neuropathic pain were the age at the onset, the attack type of optic neuritis, the attack type of myelitis, length of spinal cord involvement, localization of thoracic lesion, optic lesion, upper thoracic lesions, lower thoracic lesions, extended spinal cord lesions (≥ 3 spinal lesions), extended thoracic lesions (≥ 4 thoracic lesions), intravenous immunoglobulin and mycophenolate mofetil. Multivariate regression analysis showed that extended thoracic lesions (OR 20.21 [1.18–346.05], P = 0.038) and age (OR 1.35 (1–1.81) P = 0.050) were independently associated with neuropathic pain among NMOSD patients and that gender (OR 12.11 (0.97–151.64) P = 0.053) might be associated with neuropathic pain among NMOSD patients.ConclusionExtended thoracic lesions (≥ 4 thoracic lesions), age and gender might be independent risk factors of neuropathic pain among patients with NMOSD. However, with a small sample size and predominantly female, caution must be applied and these results need validating in further cohorts.

Experiences of nurses working in nurse-led clinics in Traditional Chinese Medicine hospitals: A focused ethnographic study.

Traditional Chinese Medicine (TCM) nurse-led clinics (NLC) is an innovative working model in China, representing the specialization and extension of nurses' role. However, as a pioneer in TCM nursing, this new model of working is facing both opportunities and challenges because it is known little about the operational status of NLCs. To explore the experiences of nurses who work in NLC in TCM hospitals. A focused ethnographic study was conducted in three TCM hospitals affiliated with Guangzhou University of Chinese Medicine. We interviewed eleven nurses in those hospitals and observed seven of them working with patients. We used snowball sampling for data collection including interview, non-participant observation and documents from medical records. All the data were processed as following steps: (a) coding for descriptive labels; (b) sorting for patterns; (c) identifying outliers or negative cases; (d) generalizing with construction and theories and (e) noting reflective remarks. Nurse-led clinics help nurses develop their skills and knowledge that are highly recognized by public since they meet the growing needs of patients and also relieve the workload of physicians in the hospitals. However, lack of specialization is still a major challenge in NLCs due to insufficiency of full-time staff with specialized education, nurse-led practice without standardized guidelines, restrictions on prescription right of nurses, and also inadequate support from hospitals. As a revolutionary innovation of working model for nurses in TCM hospitals, NLCs could improve quality of care and lead to a comprehensive promotion of nursing career. However, there are several challenges on providing high quality care for patients whilst improving educational development of nurses. This study suggests that nurses, hospital administration and the government should cooperate with each other to develop standard nursing programs for NLCs. It is imperative to identify nursing roles, collect available resources, and develop supportive policies and training programs to enhance the quality of NLCs.

Investigating the effects of Liushen Capsules on the metabolome of seasonal influenza: A randomized clinical trial.

Background: Traditional Chinese Medicines (TCMs) are effective strategies for preventing influenza infection. Liushen Capsules can inhibit influenza virus proliferation, significantly mitigate virus-induced inflammation and improve acute lung injury in vitro or in vivo. However, the efficacy and safety of LS in clinical trials, and the role of LS in regulating metabolites in patients are not well known. Materials and methods: A randomized, double-blind, placebo-controlled clinical trial was designed in this study. All participants were enrolled between December 2019 and November 2020. The efficacy and safety were assessed by primary efficacy endpoint ((area under the curve (AUC) analysis)) and secondary endpoint (individual scores for each symptom, remission of symptoms, and rates of inflammatory factors). The serum samples were collected from patients to detect the levels of inflammatory factors using RT-PCR and to identify metabolites using a non-targeted metabolomics ultra-performance liquid chromatography-tandem mass spectrometry (LC-MS). Results: 81 participants from The Second Affiliated Hospital of Guangzhou University of Chinese Medicine and the First Affiliated Hospital of Guangzhou Medical University were completed the full study. After 14 days of intervention, the area under the curve (AUC) of the total symptom scores in LS group was significantly smaller than that in Placebo group (p < 0.001). Alleviation of sore throat, cough and nasal congestion in the LS group was significantly better than that in the Placebo group. The time and number to alleviation of symptoms or complete alleviation of symptoms in LS group was significantly better than that in Placebo group. The adverse effects of clinical therapy were slightly higher in LS group than in Placebo group, but there was no statistical difference. After 14 days of LS intervention, the levels of IL-1ra, Eotaxin, IFN-γ, IL-6, IL-10, IL-13, SCF and TRAIL in serum of participants with influenza infection were significantly decreased compared with Placebo group. It was observed that there were significant differences in the serum metabolic profiles between start- and end- LS groups. Further correlation analysis showed a potential regulatory crosstalk between glycerophospholipids, sphingolipids fatty acyls and excessive inflammation and clinical symptoms. Importantly, it may be closely related to phospholipid, fatty acid, arachidonic acid and amyl-tRNA synthesis pathway metabolic pathways. Conclusion: The study showed there were no clinically significant adverse effects on LS, and a significant improvement in influenza-like symptomatology and inflammatory response in patients treated with LS. Further analysis showed that LS could significantly correct the metabolic disorders in the serum metabolite profile of the patients. This provided new insights into the potential mechanism of LS for the treatment of influenza.

Effect of electroacupuncture on gastrointestinal function of patients after laparoscopic cholecystectomy under general anesthesia

To observe the effects of electroacupuncture at bilateral Zusanli(ST36), Shangjuxu(ST37), and Sanyinjiao (SP6) acupoints on gastrointestinal function after laparoscopic cholecystectomy under general anesthesia. A total of 150 patients(American Society of Anesthesiologists［ASA］ grades Ⅰ and Ⅱ) undergoing laparoscopic cholecystectomy in the Department of Hepatobiliary Surgery of the First Affiliated Hospital of Guangzhou University of Chinese Medicine were randomly assigned into three groups: electroacupuncture group (n=50), simple acupuncture group (n=50), and control group (n=50). Patients in the control group received routine treatment；on the basis of routine treatment, patients in the simple acupuncture group were acupunctured at bilateral ST36, ST37 and SP36；patients in the electroacupuncture group were treated with electroacupuncture at bilateral ST36, ST37 and SP36（50 Hz，5 mA）. In both simple acupuncture group and electroacupuncture group, the corresponding treatments were conducted 1 h after surgery, Patients as well as in the morning (8:00-10:00) and afternoon (14:00-16:00) on the first day after surgery, 30 min each time. The time of bowel sound recovery, the time to the first postope-rative exhaust and defecation, the time of postoperative fluid diet recovery, abdominal pain score, and gastrointestinal reaction score were recorded and analyzed. Compared with the control group, the electroacupuncture group and the simple acupuncture group showed shortened time of bowel sound recovery, shortened time to the first postoperative exhaust and defecation, and shortened time of postoperative liquid diet recovery (P<0.01), as well as decreased postoperative abdominal pain score and gastrointestinal reaction score (P<0.01). Furthermore, the time of bowel sound recovery, the time to the first postoperative exhaust and defecation, and the time of postoperative liquid diet recovery were shortened in the electroacupuncture group compared with those in the simple acupuncture group (P<0.01). The total effective rate of electroacupuncture group was 94.0% (47/50), the total effective rate of simple acupuncture group was 88.0% (44/50), significantly higher than 78.0% (39/50) in the control group (P<0.05). Both electroacupuncture and simple acupuncture can promote the recovery of gastrointestinal function in patients after laparoscopic cholecystectomy under general anesthesia, and electroacupuncture is superior to simple acupuncture,but they have no significant difference in alleviating postoperative abdominal pain and gastrointestinal reactions.

Analysis and Research on the Rehabilitation Effect of Physical Exercise on College Students' Mental Depression Based on Multidimensional Data Mining.

In order to explore the physical exercise and psychological changes of college students, this study adopts the method of multidimensional data mining, taking 23,146 undergraduates from a university in Guangzhou, Guangdong Province, as the research object. On the basis of summarizing and analyzing the previous research literature, this study expounds the development background, current situation, and future challenges of multidimensional data mining technology. This paper introduces the methods and principles of sample selection and multidimensional assessment of the physical and mental depression of college students, analyzes the physical health status of college students, summarizes the psychological changes of college students before and after the intervention, and discusses the relationship between physical exercise and mental health of college students. In addition, this paper analyzes the influencing factors and psychological changes of college students' physical exercise and puts forward suggestions for improving the physical and mental health of college students. The results of this study show that with increasing age, college students have a lower risk of moderate anxiety and mild depression; girls are more prone to mild depression than boys; rural college students are more prone to mild, moderate anxiety; college students with nonmedical backgrounds were more likely to experience moderate anxiety than college students with medical backgrounds. During the intervention control period, continuous connection with others may encourage college students to actively use internal resources to actively cope with obstacles and setbacks, and as a protective factor, psychological resilience can appropriately weaken the association between risk factors in life and anxiety and relieve anxiety. The results of this study can provide a reference for further research on the physical exercise and psychological changes of college students.