Non-uniform high-temperature large heat flux is commonly encountered in engineering applications, posing challenges to heat transfer processes and affecting system performance. High temperature heat pipes offer an effective solution to mitigate the adverse effects of non-uniform heat flux by leveraging the unique characteristics of their inner alkali metal (or alloy) working fluid, such as high latent heat of vaporization, strong heat flux density, and ability to operate at elevated temperatures. These features enable high temperature heat pipes to achieve excellent isothermal and uniform heat transfer performance, thereby improving overall thermal management in heat transfer systems. Building upon the investigation of the original high temperature heat pipe, this study designed and fabricated a specially shaped high temperature heat pipe with a spherical crown surface as the evaporator. Experimental research was conducted to assess its frozen start-up performance and heat transfer characteristics under the influence of axial non-uniform heat flux. The results were also analyzed theoretically, providing valuable insights into the frozen start-up performance and heat transfer performance of the high temperature heat pipe in the presence of non-uniform heat flux conditions. The analysis results reveal several important findings: (1)The high temperature heat pipe demonstrates its capability to convert axial non-uniform high-temperature large heat flux into a uniform heat flux, thus achieving excellent uniform heat transfer performance. (2)The theoretical solution obtained through the lumped heat capacity analysis method shows satisfactory agreement with the actual frozen start-up process of the high temperature heat pipe. This theoretical reference can aid in the transient analysis of the frozen start-up process under the influence of axial non-uniform high-temperature large heat flux. (3)The experiment investigated the influence of heating power on heat transfer performance and temperature uniformity. The results indicate that the temperature uniformity of the high temperature heat pipe exhibits a trend of initially increasing and then decreasing. Specifically, the best temperature uniformity is achieved when the heating power is 1084.7 W. Moreover, when the heating power is 1197.9 W, the high temperature heat pipe exhibits the lowest equivalent thermal resistance of 0.0265 K/W, indicating the best heat transfer performance. (4) The variable power heating approach demonstrates that increasing the heating power leads to an extension of the effective length of the heat pipe. The most favorable heat transfer performance and temperature uniformity are observed when the heating power is set to 1133.7 W, allowing the full length of the condenser of the high temperature heat pipe to participate actively in the heat transfer process. These results can provide quantitative experimental data and theoretical references for improving the thermal shock of non-uniform high-temperature large heat flux.