Unfavorable Sites Research Articles

Breast carcinomatosis and treatment. A practical approach to the treatment of disseminated carcinoma of the breast.

A systemic treatment regime is presented for the management of disseminated carcinoma of the breast based on the dominant site of metastasis. Additional factors, such as menopausal status and length of free interval are considered in management. Treatment is suggested depending on whether the dominant site of the metastasis is defined as favorable or unfavorable. Admittedly brain metastasis and inflammatory breast carcinoma are special unfavorable sites requiring special management. It is hoped that attention to the dominant site of metastasis will provide a more rational basis for management of disseminated carcinoma of the breast.

THE LENGTH, TANGENTIAL DIAMETER, AND LENGTH/WIDTH RATIO OF CONIFER TRACHEIDS

In the gradual enlargement of tracheid dimensions which takes place outward from the pith in the stem and branches, growth in cell length outstrips that in tangential width so that the length/width ratio rises. Largest tracheids are usually found in the inner wood of lateral roots, where the length/width ratio is highest. Interspecific and interregional differences follow a similar pattern of relationship with respect to cell dimensions. As a rule, species or races which inhabit unfavorable sites have comparatively small cells with a low length/width ratio. Species which populate better sites and have greater growth potential are characterized by longer cells and a higher length/width ratio. Indications exist of a positive relationship between height growth, tracheid length, and the length/width ratio. On the other hand, increased radial growth in mature trees is accompanied by reduction in mean cell length and a lowering of the length/width ratio.