Abstract As a generalization of Einstein’s theory, Horava-Lifshitz has attracted significant interests due to its healthy ultraviolet behavior. In this paper, we analyze the impact of the Horava-Lifshitz corrections on the gravitomagnetic field. We propose a new planetary gravitomagnetic field measurement method with the help of the space-based laser interferometry, which is further used to constrain the Horava-Lifshitz parameters. Our analysis shows that the high-precision laser gradiometers can indeed limit the parameters in Horava-Lifshitz gravity and improve the results by one or two orders when compared with the existing theories. Our novel method provides insights into constraining the parameters in the modified gravitational theory, which facilitates a deeper understanding of this complex framework and paving the way for potential technological advancements in the field.