120 men (51,5±2,5 years old) with arterial hypertension stage П-Ш were examined. From the first days of stay of these patients in the clinic, a physical therapy low-intensity UHF radiation frequency of 1000 MHz with a power of 0.1 μw was included in the complex therapy. On the background of a drug therapy, there was a statistically significant increase of NO level by 12,4% (p=0,039) and ACE by 11,8% (p=0,05). A month later after treatment, the authors observed a decrease in the concentration of the soluble form of receptors of the 1st type to AHT-II by 22,4% (p=0,017). In the group of patients who received additional physical therapy, there was a decrease in renin activity by 19,3% (p=0,021), RAHT-Π by 18,8% (p=0,023). A month later, in these patients there was a further decrease in the concentration of RAHT-II by 52,8% (p=0,001), ACE by 12,3% (p=0,037), AHT-II by 13,4% (p=0,033), an endothelin level by 10,7% (p=0,051) and hsCRP by 13,2% (p=0,044). An increase in the concentration of NO level by 11.4% (p=0.05) was revealed.
 
 Thus, the use of low-intensity UHF physiotherapy in treatment of hypertension contributes to a reduction of endo-thelial dysfunction and vasopressor activity mechanisms with preservation of the achieved effects within one month after discharge the patient from hospital.
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