We review the main petrologic and geochemical features of magmatic rocks from continental arcs compared to their intra-oceanic equivalents. Both types share a number of characteristics, including their typical HFSE-depleted incompatible element patterns and isotopic Sr, Nd, Pb and Hf features, intermediate between those of N-MORB and continental crust. They are thought to derive from the partial melting of the mantle wedge metasomatized by fluids emanating from the downgoing plate. They are dominantly hydrous fluids provided by the breakdown of amphibolites and antigorite serpentinites, but a significant role is attributed to felsic hydrous melts derived from oceanic metabasalts and associated sediments. The more enriched character of magmas from continental arcs with respect to those from intra-oceanic arcs is ascribed to their genesis from a less depleted mantle wedge in a milder thermal regime, to the enrichment of their source via subduction erosion of the continental margin, and finally to their contamination during ascent and storage within a thicker crust.