Historically, the world’s geopolitical landscape has been replete with conflicts, from those of Ancient Mesopotamia to those in today’s Middle East and Africa. As in other world regions, parts of sub-Saharan Africa have, for decades, been trapped in a vicious cycle of conflicts and violence—in ethnopolitical and ethnoreligious contexts, even as foreign direct investment on the continent has increased 50% since 2005 and as the gross national product has increased significantly in countries such as Angola, Botswana, Kenya, Nigeria, and Rwanda, all of which are attracting international investors. This article examines the nation-building role of public relations by applying the general theory of relationship management, which is based on Grunig-Hunt two-way symmetrical model of public relations, to Sudan and Nigeria as a two-nation case study. It offers theory-informed guidelines that African states can use in managing conflicts and in developing communication strategies that engage stakeholders of disparate theological leanings at the individual level. The goal is to use communication strategies that emphasize mutually respectful Muslim-Christian dialogue on intractable, sensitive issues that have morphed into a bane of the economically burgeoning sub-Saharan African region, particularly.