Two-dimensional Spatial Resolution Research Articles

P‐49: Angular Dependent Point Spread Function Analysis for Virtual Reality Head Mounted Displays

We demonstrate a point spread function method for measuring the angular dependence of the spatial resolution of a virtual reality head mounted display. The angular dependence of spatial resolution of the imaging detector was characterized to remove the detector's contribution at each angular location measured on the VR HMD. This method allows measuring the twodimensional spatial resolution and modulation transfer function.

Evaluation of deep-learning image reconstruction for chest CT examinations at two different dose levels.

The aims of the present study were to, for both a full-dose protocol and an ultra-low dose (ULD) protocol, compare the image quality of chest CT examinations reconstructed using TrueFidelity (Standard kernel) with corresponding examinations reconstructed using ASIR-V (Lung kernel) and to evaluate if post-processing using an edge-enhancement filter affects the noise level, spatial resolution and subjective image quality of clinical images reconstructed using TrueFidelity. A total of 25 patients were examined with both a full-dose protocol and an ULD protocol using a GE Revolution APEX CT system (GE Healthcare, Milwaukee, USA). Three different reconstructions were included in the study: ASIR-V 40%, DLIR-H, and DLIR-H with additional post-processing using an edge-enhancement filter (DLIR-H + E2). Five observers assessed image quality in two separate visual grading characteristics (VGC) studies. The results from the studies were statistically analyzed using VGC Analyzer. Quantitative evaluations were based on determination of two-dimensional power spectrum (PS), contrast-to-noise ratio (CNR), and spatial resolution in the reconstructed patient images. For both protocols, examinations reconstructed using TrueFidelity were statistically rated equal to or significantly higher than examinations reconstructed using ASIR-V 40%, but the ULD protocol benefitted more from TrueFidelity. In general, no differences in observer ratings were found between DLIR-H and DLIR-H + E2. For the three investigated image reconstruction methods, ASIR-V 40% showed highest noise and spatial resolution and DLIR-H the lowest, while the CNR was highest in DLIR-H and lowest in ASIR-V 40%. The use of TrueFidelity for image reconstruction resulted in higher ratings on subjective image quality than ASIR-V 40%. The benefit of using TrueFidelity was larger for the ULD protocol than for the full-dose protocol. Post-processing of the TrueFidelity images using an edge-enhancement filter resulted in higher image noise and spatial resolution but did not affect the subjective image quality.

A time-resolved imaging system for the diagnosis of x-ray self-emission in high energy density physics experiments.

A diagnostic capable of recording spatially and temporally resolved x-ray self-emission data was developed to characterize experiments on the MAGPIE pulsed-power generator. The diagnostic used two separate imaging systems: a pinhole imaging system with two-dimensional spatial resolution and a slit imaging system with one-dimensional spatial resolution. The two-dimensional imaging system imaged light onto the image plate. The one-dimensional imaging system imaged light onto the same piece of image plate and a linear array of silicon photodiodes. This designallowed the cross-comparison of different images, allowing a picture of the spatial and temporal distribution of x-ray self-emission to be established. The designwas tested in a series of pulsed-power-driven magnetic-reconnection experiments.

Nanoscale Detection of Subcellular Nanoparticles by X-Ray Diffraction Imaging for Precise Quantitative Analysis of Whole Cancer Cells.

Nanoparticles show great potential for drug delivery systems in cancer treatment and diagnosis, which mainly rely on the interaction between nanoparticles and living cells. However, there is still a lack of accurate and large field-of-view imaging techniques to reveal the aggregation and distribution behavior of nanoparticles in whole cancer cells without being destroyed. Here, we demonstrated quantitative imaging of unstained and intact mouse breast cancer cells (4T1) containing 50 nm gold nanoparticles (Au@citrate NPs) using an X-ray scanning coherent diffraction imaging (ptychography) technique in a large field-of-view. A two-dimensional spatial resolution of 17 nm was achieved on the 4T1 cell. We combine X-ray ptychography and equally sloped tomography (EST) to perform three-dimensional structural mapping, distribution, and aggregation behavior of Au@citrate NPs in cancer cells. By taking full advantage of the large field-of-view, high-resolution, and quantitative imaging technique, the single intracellular Au@citrate NPs are observed and the amount of Au@citrate NPs in aggregations can be accurately quantified. In addition, the morphological changes of lysosomes containing Au@citrate NPs can be observed in the high-contrast mass density images. This study provides an approach for exploring quantitative analysis and physiological delivery of nanomaterials in intact cancer cells at nanoscale resolution, which may greatly benefit the interdisciplinary research of material science, nanomedicine, and nanotoxicology.

On-machine measurement method for micro-structured surface by integral imaging with workpiece rotating technique

To measure large and heavy micro-structured workpieces in situ and improve the measurement accuracy, which strongly depends on the environment during the measurement of micro-structured surfaces, a workpiece rotating technique is proposed. This method utilizes the precise rotation of machine tools to drive the workpiece and records a set of elemental image arrays for the pickup stage to overcome the upper-resolution limit imposed by the Nyquist sampling theorem, which allows the increase in the two-dimensional spatial resolution of the computed depth images in integral imaging. By extracting the depth position, we can obtain accurate depth information and measurement results for micro-structured surfaces. We carried out simulations and experiments to demonstrate the proposed method, and the results show the feasibility of our method.

4D Imaging of ZnO-Coated Nanoporous Al2O3 Aerogels by Chemically Sensitive Ptychographic Tomography: Implications for Designer Catalysts

The 3D chemical structure (4D spectromicroscopy) of nanoporous Al2O3 aerogels coated with ZnO by atomic layer deposition (ALD) was studied by multienergy scanning transmission X-ray microscopy. These materials are representative of a class of designer catalysts in which the nanoporous support is prepared separately from the active catalyst material, which is subsequently introduced by ALD, thereby allowing independent optimization of the morphology, chemistry, and spatial distribution of the support and catalyst. The samples studied were prepared by Ga ion and Xe plasma focused ion beam (FIB) milling as well as drop casting from water suspension. Zn L and Al K edge spectra of six samples with three different ZnO loadings were measured to investigate how loading and different sample preparation methods affect the 3D distribution of the ZnO and Al2O3. Scanning transmission X-ray microscopy (STXM) and ptychographic imaging at two energies each at the Zn L3 and Al K edge were measured. The ptychography data were analyzed by using the SHARP reconstruction code to generate quantitative 2D chemical maps of the Al2O3 and the ZnO. The STXM and ptychography maps were then measured at a sequence of tilt angles, covering up to 160° of rotation. The 3D structure of the ZnO and Al2O3 was derived from the tilt series data by tomographic reconstruction using a compressed sensing algorithm. A two-dimensional spatial resolution (half-period) of 6 nm, measured by Fourier ring correlation, and a 3D spatial resolution (half-period) of 9 nm, measured by Fourier shell correlation, were achieved when using the COSMIC beamline at the Advanced Light Source (ALS). The results show that for all of the ZnO loadings studied there is nonuniform coverage of the ZnO on the Al2O3 aerogel framework. In addition, we found that both FIB methods create sample artifacts, although the distortion was less with Xe plasma than Ga ion FIB.

Optimization of Discharge Parameters for a Glow Discharge Emission Spectrograph with Two-dimensional Spatial Resolution

Optimization of Discharge Parameters for a Glow Discharge Emission Spectrograph with Two-dimensional Spatial Resolution

A ceramic GEM-based neutron beam monitor for China Spallation Neutron Source

With the development of the new generation of high-flux pulsed neutron facilities, it is necessary that the neutron beam monitors have the characteristics of wavelength resolution and long-term stability, as well as high counting rates and two-dimensional(2D) spatial resolution. In this paper, a novel neutron beam monitor was developed using a single ceramic GEM(Gas Electron Multiplier) at China Spallation Neutron Source(CSNS). Its validation of the wavelength spectra measurement was verified via comparisons with measurements made with an ORDELA 4562N monitor. In addition, it was demonstrated that this neutron beam monitor was able to measure the beam profile of total and sliced wavelengths. The maximum counting rate was about 1.5 MHz by using an X-ray source. The RSD (the relative standard deviation) of instability fluctuations was approximately 0.5% during continuous operations of 40 h. The results show that the ceramic GEM-based neutron beam monitor can satisfy the demands of the high-flux neutrons measurement, and it has been regarded as a standard solution to the neutron beam monitor at CSNS.

Imaging biosensor based on planar optical waveguide

A biosensing technique with a two-dimensional spatial resolution based on a planar optical waveguide is presented. The thickness of the waveguide is chosen such that the wavelength of the waveguide mode is located between the maxima of the blue and green pixels of a color camera. A prism based Kretschmann-like configuration is used for waveguide excitation. The prism is placed between crossed polarizers to obtain the waveguide resonance peak. The spectral shift of the resonance peak is determined through the normalized differences in intensities of the blue and green pixels at each point of the color camera. The spatial distribution of resonance wavelength shifts across the camera reflects the spatial distribution of changes in the thickness of the adsorbate over the sample. The sensitivity, dynamic range, and simplicity of practical implementation of this biosensor are compared with those of an imaging biosensor based on photonic crystal surface mode.

High-energy X-ray radiography of laser shock loaded metal dynamic fragmentation using high-intensity short-pulse laser.

The dynamic fragmentation of shock-loaded high-Z metal is of considerable importance for both basic and applied science. The areal density and mass-velocity distribution of dynamic fragmentation are crucial factors in understanding this issue. Experimental methods, such as pulsed X-ray radiography and proton radiography, have been utilized to obtain information on such factors; however, they are restricted to a complex device, and the spatial resolution is in the order of 100 μm. In this work, we present the high-quality radiography of the dynamic fragmentation of laser shock-loaded tin, with good two-dimensional (2D) spatial resolution. Dynamic fragmentation is generated via high-intensity ns-laser shock-loaded tin. A high-energy X-ray source in the 50-200 keV range is realized by the interaction of a high-intensity ps-pulse with an Au microwire target, attached to a low-Z substrate material. A high 2D resolution of 12 μm is achieved by point-projection radiography. The dynamic-fragmentation radiography is clear, and the signal-to-noise ratio is sufficiently high for a single-shot experiment. This unique technique has potential application in high-energy density experiments.

Four-Dimensional Imaging of ZnO-Coated Alumina Aerogels by Scanning Transmission X-ray Microscopy and Ptychographic Tomography

Functional porous materials are of increasing importance in energy conversion and catalysis. Improved analysis is needed to guide optimization. Four-dimensional (4D) imaging [chemical mapping in three-dimensional (3D) by spectro-tomography] of an Al2O3 aerogel coated with ZnO by atomic layer deposition was performed using soft X-ray ptychography at the Zn L-edge. A two-dimensional spatial resolution of 14(2) nm was achieved. Visualizations of the 3D chemical structure are provided. The degree of ZnO coverage of the surface of the Al2O3 aerogel framework in two different samples was estimated and found to be both thicker and less homogeneous than expected. Other analyses of the 4D results, including the degree of contact between Al2O3 and ZnO, were extracted from the reconstructed 3D data. This pioneering soft X-ray spectro-ptycho-tomography study will anchor further studies of functional porous materials.

Diagnosis of atmospheric pressure helium surface micro-discharge by two-dimensional temporal and spatial resolved emission spectroscopy

The time dependence of the spectral emission of atmospheric pressure surface micro-discharge (SMD) in helium has been investigated with a two-dimensional spatial resolution. The time-resolved emission spectra from OH (309 nm), N2+ (391.4 nm), He (706.5 nm), and O (777.4 nm) behave differently. The results indicate that direct electron impact excitation dominates the generation of the plasma emission in the middle part of the rim electrode where the discharge event originates during the initial period. However, the fan-shaped diffusion of the discharge patterns head is principally due to Penning ionization and charge transfer reaction in later phases. Furthermore, the dynamic evolution of SMD emission pattern has a bullet-like structure in the negative half cycle while it looks like a glow in the positive half cycle. It implies that the polarity of applied voltage plays an important role in the dynamics of the SMD emission patterns.

High-Resolution Imaging of Polymer Electrolyte Membrane Fuel Cell Cathode Layers by Soft X-ray Spectro-Ptychography

Polymer electrolyte membrane fuel cells (PEMFCs) are a promising and sustainable alternative to internal combustion engines for automotive applications. Polymeric perfluorosulfonic acid (PFSA) plays a key role in PEMFCs as a proton conductor in the anode and cathode catalyst layers and in the electrolyte membrane. In this study, spectroscopic scanning coherent diffraction imaging (spectro-ptychography) and spectro-ptychographic tomography were used to quantitatively image PFSA ionomers in PEMFC cathodes in both two and three dimensions. We verify that soft X-ray ptychography gives significant spatial resolution improvement on soft matter polymeric materials. A two-dimensional spatial resolution of better than 15 nm was achieved. With better detectors and brighter and more coherent X-ray beams, radiation-sensitive PFSA ionomers will be visualized with acceptable levels of chemical and structural modification. This work is a step toward visualization of ionomers in PEMFC cathodes at high spatial resolution ...

Features of Short-Period Oscillations of Microwave Emission from the Solar Active Region before the Flare

The radiation of microwave sources above sunspots at a frequency of 17 GHz gives information about the parameters of solar plasma in the regions where the magneti-field strength is B ~ 2000 G in the transition region between the chromosphere and corona. Short-period oscillations (with a period of several minutes) of microwave emission from solar active regions (ARs) reflect wave processes in magnetic flux tubes of sunspots. Short-period oscillations of microwave emission from AR NOAA 12242 before two flares on December 17, 2014 are analyzed. This analysis is based on solar radio images obtained by means of the Nobeyama Radio Heliograph with a 10″−15″ two-dimensional spatial resolution. The radio maps of the whole solar disk were synthesized in a nonstandard mode with a cadence of 10 s and an averaging time of 10 s. An increase in the power of about ten-minute oscillations of microwave radiation approximately 40 to 50 min before the M1.5 flare (01: 00 UT) is found. On the same day, an increase in the power of ten-minute oscillations is observed about 60 min before the M8.7 flare (04: 42 UT). This effect is similar to the effect found earlier by two groups of authors independently for three-minute oscillations—namely, they observed a sharp increase in three-minute oscillations 15 to 20 min before the radio burst accompanying the flare. The effect in question may be interpreted as an relationship ofMHD waves propagating along the magnetic flux tube of a sunspot and the onset of the solar flare.

Investigation of Wavenumber Domain Imaging Algorithm for Ground-Based Arc Array SAR

Ground-based synthetic aperture radar (GB-SAR) has become an important technique for remote sensing deformation monitoring. However, most of the existing GB-SAR systems realize synthetic aperture by exploiting two closely spaced horn antennas to move along a linear rail. In order to obtain higher data acquisition efficiency and a wider view angle, we introduce arc antenna array technology into the GB-SAR system, which realizes a novel kind of system: ground-based arc array SAR (GB-AA-SAR). In this paper, we analyze arc observation geometry and derive analytic expressions of sampling criteria. Then, we propose a novel wavenumber domain imaging algorithm for GB-AA-SAR, which can achieve high image reconstruction precision through numerical solutions in the wavenumber domain. The proposed algorithm can be applied in wide azimuth view angle scenarios, and the problem of azimuth mismatch caused by distance approximation in arc geometric efficient omega-k imaging can be solved successfully. Finally, we analyze the two-dimensional (2D) spatial resolution of GB-AA-SAR, and verify the effectiveness of the proposed algorithm through numerical simulation experiments.

Two-dimensional heat transfer coefficients with simultaneous flow visualisations during two-phase flow boiling in a PDMS microchannel

Infrared (IR) thermography was combined with simultaneous high speed flow visualisation and pressure measurements from integrated pressure sensors inside the microchannel, in order to produce two-dimensional (2D) high spatial and temporal resolution two-phase heat transfer coefficient (HTC) maps across the full domain of a polydimethylsiloxane (PDMS) high aspect ratio (a = 22) microchannel (Dh = 192 μm). High spatial and temporal resolution two-dimensional wall temperature measurements and pressure data were obtained for a range of mass fluxes (G = 7.37–298 kg m−2 s−1) and heat fluxes (q = 13.64–179.2 kW m−2) using FC-72 as the working liquid. The 3D plots of HTC provided fine details of local variations during bubble nucleation, confinement, elongated bubble, slug flow and annular flow regime. The optical images from the channel top revealed the local flow regimes and were correlated with simultaneous thermal images obtained from the channel base. The 3D plots of the 2D two-phase heat transfer coefficient with time across the microchannel domain were correlated with vapour-liquid dynamics and liquid film thinning (from the contrast of the optical images) which caused suspected dryout. The correlation between the synchronised at the same frame rate high-resolution thermal and optical images will assist in a better understanding of the heat transfer mechanisms during two-phase flow boiling in microchannels. This work intends to give a better insight into heat transfer coefficient spatial variation during flow instabilities with two-dimensional heat transfer coefficient plots as a function of time during a cycle of liquid–vapour alternations.

Ultrafast all-optical imaging technique using low-temperature grown GaAs/AlxGa1 − xAs multiple-quantum-well semiconductor

We report and experimentally demonstrate an ultrafast all-optical imaging technique capable of single-shot ultrafast recording with a picosecond-scale temporal resolution and a micron-order two-dimensional spatial resolution. A GaAs/AlxGa1−xAs multiple-quantum-well (MQW) semiconductor with a picosecond response time, grown using molecular beam epitaxy (MBE) at a low temperature (LT), is used for the first time in ultrafast imaging technology. The semiconductor transforms the signal beam information to the probe beam, the birefringent delay crystal time-serializes the input probe beam, and the beam displacer maps different polarization probe beams onto different detector locations, resulting in two frames with an approximately 9 ps temporal separation and approximately 25 lp/mm spatial resolution in the visible range.

Towards a microchannel-based X-ray detector with two-dimensional spatial and time resolution and high dynamic range.

X-ray detectors that combine two-dimensional spatial resolution with a high time resolution are needed in numerous applications of synchrotron radiation. Most detectors with this combination of capabilities are based on semiconductor technology and are therefore limited in size. Furthermore, the time resolution is often realised through rapid time-gating of the acquisition, followed by a slower readout. Here, a detector technology is realised based on relatively inexpensive microchannel plates that uses GHz waveform sampling for a millimeter-scale spatial resolution and better than 100 ps time resolution. The technology is capable of continuous streaming of time- and location-tagged events at rates greater than 10(7) events per cm(2). Time-gating can be used for improved dynamic range.

Resolution enhancement in integral microscopy by physical interpolation.

Integral-imaging technology has demonstrated its capability for computing depth images from the microimages recorded after a single shot. This capability has been shown in macroscopic imaging and also in microscopy. Despite the possibility of refocusing different planes from one snap-shot is crucial for the study of some biological processes, the main drawback in integral imaging is the substantial reduction of the spatial resolution. In this contribution we report a technique, which permits to increase the two-dimensional spatial resolution of the computed depth images in integral microscopy by a factor of √2. This is made by a double-shot approach, carried out by means of a rotating glass plate, which shifts the microimages in the sensor plane. We experimentally validate the resolution enhancement as well as we show the benefit of applying the technique to biological specimens.

A high time and spatial resolution MRPC designed for muon tomography

A prototype of cosmic muon scattering tomography system has been set up in Tsinghua University in Beijing. Multi-gap Resistive Plate Chamber (MRPC) is used in the system to get the muon tracks. Compared with other detectors, MRPC can not only provide the track but also the Time of Flight (ToF) between two detectors which can estimate the energy of particles. To get a more accurate track and higher efficiency of the tomography system, a new type of high time and two-dimensional spatial resolution MRPC has been developed. A series of experiments have been done to measure the efficiency, time resolution and spatial resolution. The results show that the efficiency can reach 95% and its time resolution is around 65 ps. The cluster size is around 4 and the spatial resolution can reach 200 μ m.