Tumultuous Journey Research Articles

Altered Mental Status in the Solid-Organ Transplant Recipient.

Patients undergoing solid-organ transplantation (SOT) face a tumultuous journey. Prior to transplant, their medical course is characterized by organ dysfunction, diminished quality of life, and reliance on organ support, all of which are endured in hopes of reaching the haven of organ transplantation. Peritransplant altered mental status may indicate neurologic insults acquired during transplant and may have long-lasting consequences. Even years after transplant, these patients are at heightened risk for neurologic dysfunction from a myriad of metabolic, toxic, and infectious causes. This review provides a comprehensive examination of causes, diagnostic approaches, neuroimaging findings, and management strategies for altered mental status in SOT recipients. Given their complexity and the numerous etiologies for neurologic dysfunction, liver transplant patients are a chief focus in this review; however, we also review lesser-known contributors to neurological injury across various transplant types. From hepatic encephalopathy to cerebral edema, seizures, and infections, this review highlights the importance of recognizing and managing pre- and posttransplant neurological complications to optimize patient outcomes.

The Aesthetic Function of the Grotesque in E.T.A. Hoffmann’s „The Sandman”

This article explores the aesthetic intricacies of E.T.A. Hoffmann’s „The Sandman,” through the lenses of Kantian and Burkean philosophy, examining the profound implications of the grotesque within the narrative. Drawing from Kant’s notion of the sublime and Burke’s concepts of terror and delight, the article analyzes how Hoffmann masterfully intertwines elements of the grotesque to evoke a sense of astonishment and transcendence in the reader. Through an analysis of the protagonist Nathaniel’s tumultuous journey and his fraught relationship with the grotesque figure of Coppelius, we aim to elucidate how Hoffmann addresses themes of trauma, obsession, and existential dread. Furthermore, the article delves into the broader implications of the grotesque within Romantic literature, highlighting its role as a means of approaching complex psychological and societal phenomena. Ultimately, by unravelling the enigmatic connection between the narrator and Nathaniel, the article underscores how „The Sandman” emerges as a haunting enquiry into human frailty and the elusive nature of reality.

The Impact of Covid-19 on the Aviation Industry in Air Transportation

The Impact of Covid-19 on the Aviation Industry in Air Transportation

A sequence of Type Ib, IIb, II-L, and II-P supernovae from binary-star progenitors with varying initial separations

Over the last decade, evidence has accumulated that massive stars do not typically evolve in isolation but instead follow a tumultuous journey with a companion star on their way to core collapse. While Roche-lobe overflow appears instrumental for the production of a large fraction of Type Ib and Ic supernovae (SNe), variations in the initial orbital period, $P_ init $, of massive interacting binaries may also produce a wide diversity of case B, BC, or C systems, with pre-SN stars endowed from minute to massive H-rich envelopes. Focusing here on the explosion of the primary donor star, originally 12.6\ we used radiation hydrodynamics and nonlocal thermodynamic equilibrium time-dependent radiative transfer to document the gas and radiation properties of such SNe, covering Types Ib, IIb, II-L, and II-P. Variations in init $ are the root cause of the wide diversity of our SN light curves, which present single-peak, double-peak, fast-declining, or plateau-like morphologies in the $V$ band. The different ejecta structures, expansion rates, and relative abundances (e.g., H, He, and can lead to a great deal of diversity in terms of spectral line shapes (absorption versus emission strength and width) and evolution. We emphasize that Halpha is a key tracer of these modulations, and that He is an enduring optical diagnostic for the presence of He. Our grid of simulations fares well against representative Type Ib, IIb, and II-P SNe, but interaction with circumstellar material, which is ignored in this work, is likely at the origin of the tension between our Type II-L SN models and observations (e.g., of SN\,2006Y). Remaining discrepancies in the rise time to bolometric maximum of our models call for a proper account of both small-scale and large-scale structures in core-collapse SN ejecta. Discrepant Type II-P SN models, with a high plateau brightness but small spectral line widths, can be fixed by adopting more compact red-supergiant star progenitors.

A Dirty Little Secret

This article describes my tumultuous journey studying imagination in a graduate leadership seminar using an arts-based pedagogy called Performative Inquiry. Focusing on my own teaching and learning in this course, I share insights that inform my future teaching and can support colleagues interested in exploring imagination with their students. I accepted risks associated with arts-based performances and entered a shared space of vulnerability with my students. My struggles with resistance were real, and so too was the realization of the important role vulnerability plays in imagination-focused (leadership) education. I suggest that Performative Inquiry offers other (leadership) educators a powerful pedagogy and methodology for understanding imagination in their own lives and inquiring into their leadership education practices. Arts-based practices allow learners to feel their own imaginations and experience possibility by accepting invitations to be vulnerable, performing learning in a range of productive and generative ways.

Family Caregivers' Trajectories of Distress While Caring for a Person With Serious Mental Illness.

Serious mental illness (SMI) can significantly impact the lives of individuals and their families. These families often experience great emotional distress over time due to the early onset of SMI, which in turn leads to long-term trajectories and only partial recovery. However, we do not fully understand the emotional distress of family caregivers. Thus, our aim was to enrich the understanding of the lived experiences of family caregivers' emotional trajectories of distress while caring for persons with SMI. We conducted a secondary analysis using a hermeneutic approach to the narratives of seven family caregivers from a study on living with voices unheard by others. Participants' trajectories of emotional distress came forth as being thrust on an unpredictable, intensely worrisome, and indefinite journey. The following themes highlighted this tumultuous journey: fumbling in the dark trying to grasp the incomprehensible, "on your toes"-enduring unpredictability, facing different forms of fear, and battling waves of sadness and regret. Caregivers face multiple threats to their well-being and sometimes even to their health. Their distress appeared to vary according to their relationship with the person with SMI, whether they lived with the ill person, illness trajectory, and amount of violent or suicidal behavior. The results underscore the need for individualized and timely information, opportunities for dialogue with healthcare providers with and without the person with SMI, and inclusion in care planning. Caregivers who have experienced trauma, threats of violence, and rejection require special attention.

Psychoanalytic Approach and Dreams Interpretation in Surah Yusuf

This study examines specific concepts of the psychoanalytic approach related to dream interpretation and defense mechanisms within Surah Yusuf in the Holy Quran. These concepts are reevaluated from an Islamic perspective, based on the teachings of the Quran and the Sunnah of Prophet Muhammad. This article aims to discuss the psychoanalytic approach in Surah Yusuf from an Islamic viewpoint and how these concepts can be interpreted in the context of providing solace to Prophet Muhammad during challenging times. Specifically, this research investigates the tumultuous journey of Yusuf, his psychological suffering, and traumatic experiences, as well as how the Quran portrays dream interpretation and defense mechanisms in Surah Yusuf as an example of Prophet Muhammad in endurance and patience during his mission. The findings of this study contribute to a deeper understanding of psychoanalytic concepts, particularly dream interpretation and defense mechanisms, within the framework of a realistic and accurate Islamic perspective. The Islamic perspective demonstrates a strong balance between dreams and their interpretation tools, as well as between unconsciousness and defense mechanisms, ultimately fostering security, peace, and the ability to overcome traumatic experiences for individuals who hold firmly to faith and religious principles.

WORLDLY SIGNIFICANCE OF THEATERS: IREVAN STATE AZERBAIJAN DRAMA THEATER

Historically and even now, the literary and cultural environment of Azerbaijan is known both in the East and in the West. As a result of the severe tragedies, deportations, and genocides inflicted on the people of Azerbaijan, scientific and educational institutions, state institutions, museums, natural monuments, and cultural centers created in our country have suffered as much as our people. Theaters were also forced to live the fate of refugees. Today Shusha Musical Drama Theater, Aghdam State Drama Theater, Fuzili State Drama Theater continue their activities in the field of refugees. All three theaters, which have a great tradition of Armenian influence, have undoubtedly struck a blow. The annals of the Theater, which went through a tumultuous journey and was repeatedly subjected to Armenian vandalism, is a part of the historical destiny of our compatriots in the ancient lands of Azerbaijan. The article discussed the history, activity, and post-deportation activities of the Yerevan State Azerbaijan Drama Theater in exchange for all these processes. At the same time, attention was drawn here to the current situation of the Iravan State Azerbaijan Drama Theater and the works in the theater's repertoire. It was emphasized that the theater, which went through a difficult and turbulent path, goes on tours today, stages new plays, and gives successful performances. The article is dedicated to the ongoing processes related to the Yerevan State Azerbaijan Drama Theater.

Sino-Pakistan Relations: A Historical Journey of 70 Years

Pakistan-China friendship is the height of longstanding confidence, regardless of different cultures, political systems and religions. Both countries have evolved their bilateral relationship based on common values and belief systems. Pakistan recognized China in 1950. This relationship has been upgraded to a strategic partnership in 2005, signed a treaty following Friendship and Good Neighbourly relationship. Both countries have successfully managed their relationship over a long and tumultuous journey of 70 years. This study delineates Pakistan-China strategic relationships in different phases of history from 1950 to 2020.

Andrew Scull: contextualising psychiatry

Looking back can help you look forwards. Andrew Scull has spent a scholarly lifetime unpicking changing perspectives on psychiatry and mental illness: “for me it was always intriguing to think about how societies dealt with and conceived of mental disturbance”. He is now Distinguished Professor of Sociology and Science Studies at the University of California, San Diego (CA, USA), and the latest of Scull's many books, Desperate Remedies (2022), explores the tumultuous journey of psychiatry in the USA over the past 200 years.

Kievan Rus: A Tumultuous Journey Ended With War

Russia’s “Special Military Operation” against Ukraine on 24 February 2022 can be counted as the biggest ever war in Europe since World War II. The rationale of the operation, as Russian President Vladimir Putin asserts, is that Russia even could not stay safe, prosper and survive with a NATO-leaning Ukraine. Nevertheless, the present-day war is a culmination of several factors which have set the stage for a more bitter outcome between Russia and Ukraine soon. The paper attempts at analysing how the present-day Russia-Ukraine war is a culmination of conflicting claims and interests of the two countries-Russia and Ukraine, starting from Kievan Rus, and how the west dragged Moscow into a deadly war with Kyiv. In the entire gamut of analysis, Ukraine’s intertwined history and the Russian claims, NATO expansion, resurgent Russia, and oscillating Ukrainian domestic politics hinged on east-west leanings, all together have been taken into account to unfold the current crisis in a wider spectrum.

Almajid Limited: the tumultuous journey of a multigenerational enterprise in Saudi Arabia. Case study: Parts A, B, C and D

Learning outcomes Reflect on the influence of different lifecycle stages on the strategy of a family business; evaluate the impact of family, industry and company dynamics on the evolution of a family firm; assess the impact of ownership, governance and succession considerations on the sustainability of a family firm; and develop decision-making skills to overcome specific dilemmas and secure the family business longevity. Case overview/synopsis Five industries, three generations and one family business. What started off as an entrepreneur’s ambition, Almajid Limited has proven itself to a sustainable source of revenue and a diverse portfolio of businesses for multiple generations of a Saudi Arabian family. This case study offers an exclusive opportunity to follow the tumultuous journey of a Saudi family business and analyze the different phases of its evolution over seven decades and three generations. In particular, the case aims to highlight the complexities surrounding the management of a family firm and illustrate how various lifecycle stages stemming from a number of areas (e.g. family, company, industry, ownership and governance) simultaneously influence the family business strategy. Being deeply embedded in the context of Saudi Arabia, the case unveils the unique challenges of managing a family business in a conservative cultural setting. The case study is divided into four parts, with each of them putting the emphasis on a different lifecycle area of significance for the evolution of the family business. Each part culminates with the identification of an area-relevant dilemma that needs to be addressed for the family firm to be able to move into the next stage of its development. Part A focuses on the family area or axis, the Part B on the industry axis, Part C on the company axis, while Part D is based on the sustainability axis, which embraces as many as three dilemmas in relation to the ownership, governance and succession in the family firm. Moreover, each part incorporates a timeline of critical events that contributed to the emergence of a specific dilemma and a culturally-rooted anime that helps the readers visualize the story, picture somebody else’s reality, and empathize with the key protagonists of the case to achieve optimal decision-making. Complexity academic level Graduate audience: Master of Business Administration or Master of Global Entrepreneurial Management. Supplementary materials Teaching Notes are available for educators only. Subject code CSS 11: Strategy.

Intergenerational resilience in families affected by war, displacement, and migration: “It runs in the family”

ABSTRACTThis article argues for an expansion of the focus on resilience as a characteristic of the individual to one of resilience as a familial and intergenerational experience. Drawing upon a case study of a young person’s tumultuous journey from war to refuge, the authors explore the impact, challenges, and opportunities inherent within the context of war-induced flight, migration, and resettlement, with special attention to individual, family and intergenerational resilience. The authors demonstrate that in the face of adversity and loss, war-affected families do not only run from war, but are also able to repair, grow, and even pass down their adaptive capacities from the “recovery repertoire” to the next generation. Given the capacity for intergenerational resilience, it is the authors’ contention that interventions and practices aimed to support the psychosocial well-being of war-affected children must therefore consider the prominence of not only daily stressors, but also protective factors at each level of youth’s socioecological system to bolster resilience. Additionally, we argue that social work practice and interventions must broaden service options to include attention to caregiver mental health along with the mental health of the war-affected child to capture the complexities of the intergenerational transmission of both trauma and resilience.

Zinc in Ruminants: Metabolism and Homeostasis

Zinc is one of the most studied minerals of the twenty-first century as it is practically involved in every function of the body. The importance of zinc has earned it the epithet “calcium of twenty-first century.” However, the bioavailability of zinc depends on the source of zinc and the subsequent processes of digestion, absorption and metabolism. Zinc from organic sources tends to be more available to animals than from inorganic sources. The complex gastrointestinal physiology of ruminants makes these processes even more intricate. Zinc in the rumen interacts with other substances altering its fate. Absorption of zinc from the gastrointestinal tract (GIT) was a mystery until the discovery of zinc transporter proteins. These discoveries opened new gates of wisdom and understanding about the tumultuous journey of zinc molecules through the complex GIT of ruminants. The decade-old concepts of zinc homeostasis largely based on the zinc complexes are jostling through the new theories with the focus on the free zinc ions. The present review briefly elucidates the processes of metabolism and homeostasis of zinc in ruminants.

Adolphe de Waldeck, prévôt d’Utrecht (1286–1301) et futur évêque de Liège (1301–1302) : un long prélude à un bref épiscopat

This paper recounts the tumultuous journey of Adolf of Waldeck from his accession to the office of Provost of the Cathedral chapter of Utrecht (ca 1286) to his appointment as Bishop of Liège (1301). During these fifteen years, he managed to climb to the highest spheres of power in the bishopric of Utrecht and to assert himself as the most powerful clergyman after the bishop. He carried out a policy of opposition to the bishops John of Nassau (1267–1290) and John van Sierck (1291–1296), with whom he had extremely contentious relations, but was an unfailing supporter of William Berthout (1296–1301). At Berthout’s death, Adolf attempted to gain the episcopal see by becoming the key player for the House of Dampierre, for which Berthout had been the spearhead in Utrecht and which was opposed to the candidacy of Guy van Avesnes, a representative of the House of Hainaut. Thus competition in Utrecht was one of the episodes in a much broader political struggle that tore apart the Dutch principalities. The House of Hainaut stood in opposition to the House of Flanders, with support from higher authorities (the Pope, the King of France, the King of England, and the King of the Romans) favoring one or the other.

James W. Endersby and William T. Horner. Lloyd Gaines and the Fight to End Segregation.

In Lloyd Gaines and the Fight to End Segregation, James W. Endersby and William T. Horner chronicle the story of Missouri resident Lloyd Lionel Gaines and his arduous struggle to enter the University of Missouri School of Law, culminating in the Missouri ex rel. Gaines v. Canada decision, the first U.S. Supreme Court triumph against segregated education achieved by the National Association for the Advancement of Colored People (NAACP). The book traces the genesis of the Gaines case and the pioneering work of Charles Hamilton Houston, the former dean of Howard University School of Law and the visionary chief architect of the NAACP’s legal program, to defeat Jim Crow. It illuminates Gaines’s role as a precursor to important legal victories by the NAACP in the fight against segregation in higher education, including Sipuel v. Board of Regents of University of Oklahoma, McLaurin v. Oklahoma, and Sweatt v. Painter. Building on a significant body of scholarship on the NAACP’s legal strategy to end segregation, the book centers on Lloyd Gaines’s tumultuous journey. When Gaines, a Lincoln University honor graduate, sought to enter the Missouri School of Law, the university denied him admission because of his race, instead offering him a pittance to enroll in an out-of-state law school. This practice allowed segregationist states ostensibly to comply with the Plessy v. Ferguson decision while maintaining all-white institutions and avoiding the cost of establishing black graduate and professional programs.

STUDENTS’ PERCEPTIONS OF SCHOOLING: THE PATH TO ALTERNATE EDUCATION

<p style="margin: 0cm 0cm 24pt 36pt;"><span style="color: #131413; font-family: Times New Roman; font-size: medium;">Policies governing education in North America have given schools the responsibility of meeting the needs of a diverse student population, including those with emotional and behavioural difficulties (EBD). To balance their need for individualized programs with their right to inclusion in schools, students with EBD may be placed in alternate programs within a mainstream school setting. However, little is known about student experiences leading to this placement or their experiences in these programs. The purpose of this study was to explore youth’s perceptions of the factors that influenced their being placed in an alternate program for students with EBD. Six eighth-grade students participated in semi-structured interviews and created a visual map of their school trajectories. An interpretative phenomenological analysis (IPA) of the data suggested that their schooling was a tumultuous journey that contributed to their emotional, behavioural, and academic struggles, and to their placement in an alternate school program. Students described disrupted school services, lack of supports, a negative school climate, and disengaging instructional strategies as contributing to their difficulties. An understanding of the influence of school context and policy on student behaviour is necessary if we are to improve educational outcomes and properly support child and adolescent development.</span></p>

Visishtādvaita and Wahdatul-Wujūd: Points of comparison and departure

Not only in philosophy but in religion as well, concepts such as God, World and Man are discussed quite considerably. Nevertheless, an understanding of these concepts requires careful, detailed and systematic analyses. One of the methods of achieving the same is to use a comparative framework. Within Islam, Wahdatul-Wujud (Unity of Existence) is an important mystical and philosophical perspective that has witnessed a tumultuous journey. It has however played a dominant role in Islamic thought. Within Indian philosophy, Vedānta has played a very influential role. Visistādvaita as a school of thought has also played a great role to interpret core philosophical concepts of Upanishads, Bhagavad Gita and Brahma Sutras. In this research paper, we attempt to provide a comparative analysis of Visistādvaita and Wahdatul-Wujud marking out the aspects of similarity and departures. What stands out as relevant and insightful as an implication of the comparative method is an understanding of these two approaches. Wahdatul-Wujud is redefined as a panentheistic philosophy which believes that God exists inside of everything, but is at the same time, transcendent of everything. In this type ofbelief, God is seen as an eternal spark of all things, the Prime Mover. Quite similarly, Visistādvaita, on the other hand is conceived as a Qualified Non- dualistic philosophy which believes in subsuming every diverse phenomena and experience under an underlying unity.

Religion, caste, and politics in India

After Independence the Nehruvian approach to socialism in India rested upon three pillars: secularism and democracy in the political domain; state intervention in the economy; and diplomatic Non-Alignment mitigated by pro-Soviet leanings after the 1960s. These features defined the 'Indian model', and even the country's political identity. From this starting point Christophe Jaffrelot explores the manner in which some of these dimensions have been transformed over the course of time, more especially since the 1980-90s. The world's largest democracy has sustained itself by making more room, not only for the vernacular politicians of the linguistic states, but also for Dalits and OBCs, at least after the Mandal Commission report. But the simultaneous-and related-rise of Hindu nationalism has put the minorities-and secularism-on the defensive, and in many ways the rule of law is on trial too. The liberalisaton of the economy has resulted in growth but not necessarily in development: while the new middle class is changing the face of urban India, the rural areas lag behind and inequalities have become more acute. India has also acquired a new global status, that of an emerging power seeking new political and economic partnerships in Asia and in the West, where the United States remains the first choice of the Indian middle class. The traditional Nehruvian system is giving way to a less cohesive but a more active India, a country that has already become what it is against all the odds. Christophe Jaffrelot tracks India's tumultuous journey of recent decades, exploring the role of religion, caste and politics in weaving the fabric of a modern democratic state.

Aspirin

> Among the many useful discoveries which this age has made, there are very few which better deserve the attention of the public that what I am going to lay before your Lordship. > > —Reverend Edward Stone –Chipping-Norton, Oxfordshire –April 25, 1763 These prophetic words, written by Reverend Edward Stone in a 1763 letter to George Parker, the second Earl of Macclesfield, describe the results of the first clinical trial recorded in medical history.1 Stone's report on the rediscovery of the medicinal value of willow bark among subjects suffering from malarial symptoms is considered a significant milestone in the development of aspirin. Although society now takes many of its beneficial effects for granted, aspirin did not suddenly appear for medicinal use after Reverend Stone's discovery. Instead, its tumultuous journey was fueled by individual scientific curiosity, accidental discoveries, and intense business rivalry.1 No other drug is used by a greater number of people worldwide than aspirin, the benefits of which span centuries, beginning with the very first uses of willow bark by Egyptian physicians (Figure 1). Aspirin single-handedly transformed a coal-dye company into a pharmaceutical giant and has emerged as a cornerstone in the present-day therapies available for treating cardiovascular disease (CVD), pain, and inflammation. This article discusses the sentinel historical aspects of the discovery and clinical cardiovascular developments of aspirin, as well as its contemporary use in today's medical arena. Figure 1. Timeline of historical events in the development of aspirin. ### Historical Developments of Salicylates On January 20, 1862, Edwin Smith made one of the most historically important purchases of his life. Well-regarded among his peers for his keen scholarship and intricate knowledge of Egyptology, Smith purchased, for £12, 2 worn papyrus scrolls in a local Luxor street market1 that later turned out to be a formative medical textbook unlocking ancient Egyptian's practice of medicine. Although authorless, the Ebers Papyrus is 110 pages …