Tubular Fluid Reabsorption Research Articles

Dynamics of glomerular ultrafiltration in the rat. II. Plasma-flow dependence of GFR.

Dynamics of glomerular ultrafiltration in the rat. II. Plasma-flow dependence of GFR.

Potassium-induced inhibition of proximal tubular fluid reabsorption in rats

Potassium-induced inhibition of proximal tubular fluid reabsorption in rats

Effect of increases in blood pressure on pressure and reabsorption in the proximal tubule.

ARTICLESEffect of increases in blood pressure on pressure and reabsorption in the proximal tubuleTP Dresser, RE Lynch, EG Schneider, and FG KnoxTP Dresser, RE Lynch, EG Schneider, and FG KnoxPublished Online:01 Feb 1971https://doi.org/10.1152/ajplegacy.1971.220.2.444MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByRenal Autoregulation in Health and DiseaseMattias Carlström, Christopher S. Wilcox, and William J. Arendshorst1 April 2015 | Physiological Reviews, Vol. 95, No. 2Elevations in Renal Interstitial Hydrostatic Pressure and 20-Hydroxyeicosatetraenoic Acid Contribute to Pressure NatriuresisHypertension, Vol. 49, No. 3Effect of sodium delivery on superoxide and nitric oxide in the medullary thick ascending limbMichiaki Abe, Paul O'Connor, Mary Kaldunski, Mingyu Liang, Richard J. Roman, and Allen W. Cowley1 August 2006 | American Journal of Physiology-Renal Physiology, Vol. 291, No. 2Acute hypotension induced by aortic clamp vs. PTH provokes distinct proximal tubule Na+ transporter redistribution patternsPatrick K. K. Leong, Li E. Yang, Harrison W. Lin, Niels H. Holstein-Rathlou, and Alicia A. McDonough1 October 2004 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 287, No. 4Mechanisms of pressure natriuresisCurrent Hypertension Reports, Vol. 4, No. 2Effect of Renal Perfusion Pressure on Excretion of Calcium, Magnesium, and Phosphate in the Rat3 July 2009 | Clinical and Experimental Hypertension, Vol. 17, No. 8Control of Sodium Excretion: An Integrative Approach1 January 2011Response of superficial proximal convoluted tubule to decreased and increased renal perfusion pressure. In vivo microperfusion study in rats.Circulation Research, Vol. 66, No. 5Diuretic Effects of L-Threo-3,4-Dihydroxyphenylserine (L-Threo-DOPS) in Anesthetized RatsJapanese Journal of Pharmacology, Vol. 52, No. 34 Control of blood and extracellular volumeBaillière's Clinical Endocrinology and Metabolism, Vol. 3, No. 2Pressure-diuresis in volume-expanded rats. Cortical and medullary hemodynamics.Hypertension, Vol. 12, No. 2Pressure-diuresis in volume-expanded rats. Tubular reabsorption in superficial and deep nephrons.Hypertension, Vol. 12, No. 2Renal Hemodynamics and Sodium Chloride ExcretionRole of renal papillae in the regulation of sodium excretion during acute elevation of renal perfusion pressure in the rat.Hypertension, Vol. 6, No. 6_pt_1Arterial pressure and exaggerated natriuresis in spontaneously hypertensive rats.Hypertension, Vol. 3, No. 3Autoregulation of superficial nephron function in the alloperfused dog kidneyPflügers Archiv - European Journal of Physiology, Vol. 382, No. 1Renal Hemodynamic Factors and the Regulation of Sodium ExcretionAutoregulatory responses of superficial nephrons and their association with sodium excretion during arterial pressure alterations in the dog.Circulation Research, Vol. 41, No. 4The effect of an acute increase in renal perfusion pressure on sodium transport in the rat kidney.Circulation Research, Vol. 39, No. 5Quantitative aspects of autoregulation in the canine kidneyPfl�gers Archiv European Journal of Physiology, Vol. 353, No. 1Role of physical and neuroendocrine factors in proximal electrolyte reabsorptionMetabolism, Vol. 23, No. 8Correlation between luminal hydrostatic pressure and proximal tubular fluid reabsorption in the rat kidneyPfl�gers Archiv European Journal of Physiology, Vol. 350, No. 2Über die antidiuretische und saluretische Aktivität des Jugularvenenblutes narkotisierter Ratten bei einer beidseitigen Abklemmung der A. carotis communisResearch in Experimental Medicine, Vol. 160, No. 2Hydrostatic pressures in proximal tubules and peritubule capillaries in the dogKidney International, Vol. 2, No. 1 More from this issue > Volume 220Issue 2February 1971Pages 444-447 Copyright & PermissionsCopyright © 1971 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1971.220.2.444PubMed5540895History Published online 1 February 1971 Published in print 1 February 1971 Metrics

Effect of peritubular oncotic pressure changes on proximal tubular fluid reabsorption.

Effect of peritubular oncotic pressure changes on proximal tubular fluid reabsorption.

In vivo perfusion of proximal tubules of the rat: glomerulotubular balance.

ARTICLESIn vivo perfusion of proximal tubules of the rat: glomerulotubular balanceT Morgan, and RW BerlinerT Morgan, and RW BerlinerPublished Online:01 Oct 1969https://doi.org/10.1152/ajplegacy.1969.217.4.992MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByProximal Nephron1 July 2013Sodium and Chloride TransportAnalysis of Generative and Dissipative Flow-Dependent Mechanisms in Tubuloglomerular FeedbackMicropuncture techniquesKidney International, Vol. 30, No. 2Factors influencing renal sodium reabsorption in volume expansion20 June 2005Ionic requirements of proximal tubular fluid reabsorption: Flow dependence of fluid transportKidney International, Vol. 20, No. 5A mathematical model of fluid transport in the kidneyActa Physiologica Scandinavica, Vol. 112, No. 4Dependency of proximal tubular fluid transport on the load of glomerular filtrateKidney International, Vol. 20, No. 1INTRINSIC FACTORS REGULATING GLOMERULOTUBULAR BALANCEEffect of flow rate and the extracellular fluid volume on proximal urate and water absorptionKidney International, Vol. 17, No. 2Effect of perfusion rate on the fluxes of water, sodium, chloride and urea across the proximal convoluted tubuleKidney International, Vol. 11, No. 1The rational approach to the management of oedemaIrish Journal of Medical Science, Vol. 144, No. S1Variation of proximal tubular reabsorptive capacity by volume expansion and aortic constriction during constancy of peritubular capillary protein concentration in rat kidneyPfl�gers Archiv European Journal of Physiology, Vol. 356, No. 1Renal Control of Salt and Fluid Homeostasis during i. v. Saline InfusionActa Physiologica Scandinavica, Vol. 90, No. 2Comments on Kidney Dynamics and ControlIFAC Proceedings Volumes, Vol. 6, No. 4Glomeruiar-Tubular Balance: Dynamics of the Phenomenon and Analysis of its Role in the Homeostatic Defense of Extracellular Fluid Volume and CompositionIFAC Proceedings Volumes, Vol. 6, No. 4Single glomerular filtration rate of superficial and Juxta-medullary nephrons in the rat during different types of arterial hypertensionPflügers Archiv, Vol. 340, No. 2Importance of ultrafilterable plasma factors in maintaining tubular reabsorptionKidney International, Vol. 3, No. 3Effect of peritubular capillary perfusion rate on proximal sodium reabsorptionKidney International, Vol. 1, No. 6Effects of saline infusion on glomerulotubular balanceKidney International, Vol. 1, No. 2The Use of [ 14 C] and [ 3 H] Labelled Derivatives of Inulin as Tracers of Inulin «in vivo»27 September 2008 | Archives Internationales de Physiologie et de Biochimie, Vol. 80, No. 3Mathematical simulation of normal nephron function in rat and manJournal of Theoretical Biology, Vol. 31, No. 2Influence of luminal diameter and flow velocity on the isotonic fluid absorption and36Cl permeability of the proximal convolution of the rat kidneyPfl�gers Archiv European Journal of Physiology, Vol. 324, No. 4Reexamination of the split oil droplet method as applied to kidney tubulesPfl�gers Archiv European Journal of Physiology, Vol. 324, No. 4FACTORS CONTROLLING SODIUM TRANSPORT IN THE PROXIMAL TUBULE AND THEIR RELEVANCE TO CLINICAL MEDICINE1 January 1971 | Medical Journal of Australia, Vol. 1, No. 3Different correlations between plasma protein concentration and proximal fractional reabsorption in the rat during acute and chronic saline infusionPfl�gers Archiv European Journal of Physiology, Vol. 321, No. 2Simultaneous measurement of unidirectional and net sodium fluxes in microperfused rat proximal tubulesPfl�gers Archiv European Journal of Physiology, Vol. 320, No. 1 More from this issue > Volume 217Issue 4October 1969Pages 992-997 Copyright & PermissionsCopyright © 1969 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1969.217.4.992PubMed4309978History Published online 1 October 1969 Published in print 1 October 1969 Metrics

Micropuncture studies on the influence of antidiuretic hormone on tubular fluid reabsorption in rats with hereditary diabetes insipidus.

Micropuncture studies were carried out on rats with hereditary hypothalamic diabetes insipidus, in order to measure net sodium and water reabsorption in proximal convolutions and short loops of Henle during water diuresis and ADH-induced antidiuresis. Intravenous infusion of 0.15 mU ADH per minute reduced urine flow from 74.5 μl per kidney per minute to 10.8 μl, and increased urine osmolality from 117 to 605 mOsm/kg. These changes could be reversed by stopping ADH. ADH did not alter the fractional reabsorption of fluid or the reabsorptive capacity for sodium in the proximal tubules. Nor did it change glomerular filtration rates of single superficial nephrons or of the entire kidney. Fractional reabsorption of the glomerular filtrate up to the early distal convolution was significantly higher (82.0%) in water diuresis than in antidiuresis (74.4%). Since this reabsorption remained unchanged in the proximal convolutions, the decreased reabsorption during antidiuresis must have occurred in the short loops. Fractional reabsorption of sodium up to the early distal tubule was essentially identical during water diuresis and antidiuresis, indicating that ADH does not enhance urinary concentration by increasing the reabsorption of sodium from short loops.

Intrarenal control of proximal tubular reabsorption of sodium and water.

The effect of variations in the rate of peritubular capillary removal of tubular epithelial reabsorbate on net reabsorption of fluid from the proximal tubule was studied in rat kidneys by micropuncture techniques. Elevation of the renal venous pressure induced by partial occlusion of the renal vein resulted in decreased proximal tubular reabsorption. This reduction was proportional to the decrease in renal plasma flow. During control conditions an inverse linear relationship was observed between filtration fraction (CIn/Cpah) and the half time of fluid reabsorption, suggesting that an increase in the oncotic pressure in peritubular capillaries facilitates proximal tubular fluid reabsorption. Direct evidence for this hypothesis was obtained in free flow and split drop experiments in which the peritubular capillaries were perfused through micropipettes, with fluid of different oncotic pressures. When the capillary perfusate consisted of colloid-free Ringer’s proximal reabsorption was markedly depressed. AdditioC of 8 g/l00 ml of high molecular Dextran to Ringer’s restored tubular reabsorptive capacity to control levels. The results obtained in these studies demonstrate that a significant portion of tne overall net movement of fluid depends upon the rate of vascular removal of the epithelial reabsorbate.

Peritubular control of proximal tubular fluid reabsorption in the rat kidney.

Peritubular control of proximal tubular fluid reabsorption in the rat kidney.

Balance between tubular flow rate and net fluid reabsorption in the proximal convolution of the rat kidney. II. Reabsorptive characteristics during constriction of the renal artery.

In rats with hereditary Diabetes insipidus (Brattleboro strain) proximal fluid reabsorption was studied during spontaneous variations of GFR. Independent of kidney weight and arterial blood pressure total kidney GFR varied between 0.35 ml/min×gKW and 1.8 ml/min×gKW, while single nephron filtrate showed a variation between 18 nl/min×gKW and 66 nl/min×gKW. End-proximal TF/P inulin of 78 fluid samples did not correlate with filtration rate and averaged 2.38±0.55 S.D. Also, proximal transit time was independent of filtration rate with a mean of 9.7 sec±1.1 S.D. These results imply a direct correlation between mean luminal radius and filtration rate, which was demonstrated by microphotography of the renal surface.

Effect of vasopressin on proximal tubule sodium reabsorption in the dog.

ARTICLESEffect of vasopressin on proximal tubule sodium reabsorption in the dogBB Davis, FG Knox, and RW BerlinerBB Davis, FG Knox, and RW BerlinerPublished Online:01 Jun 1967https://doi.org/10.1152/ajplegacy.1967.212.6.1361MoreSectionsPDF (765 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByRenal lithium handling during water loading and subsequent d-DAVP-induced anti-diuresisEuropean Journal of Clinical Investigation, Vol. 18, No. 3THE EFFECT OF HIGH RATES OF VASOPRESSIN ADMINISTRATION ON RENAL POTASSIUM AND SODIUM EXCRETION DURING POTASSIUM LOADING IN THE SHEEP19 July 2012 | British Journal of Pharmacology, Vol. 58, No. 1BIOLOGIC ACTIVITY OF NEUROPHYSIN: NATRIURESISAnnals of the New York Academy of Sciences, Vol. 248, No. 1 NeurophysinsVasopressin dependent adenylate cyclase in single segments of rabbit kidney tubulePfl�gers Archiv European Journal of Physiology, Vol. 357, No. 3-4The Relationship of Antidiuretic Hormone to the Control of Volume and Tonicity in The HumanThe effects of 11-deoxycorticosterone and antidiuretic hormone (pitressin) on fluid exchange and electrolyte excretion by normal and starved polyuric-polydipsic rabbitsPfl�gers Archiv European Journal of Physiology, Vol. 345, No. 3Effects of ADH and dibutyryl cyclic AMP on submaxillary secretion in the dogEuropean Journal of Pharmacology, Vol. 18, No. 3Vasopressin: Effect on Deformability of Urinary Surface of Collecting Duct CellsScience, Vol. 168, No. 3935Effect of expansion of extracellular fluid volume on proximal sodium reabsorption in hyponatremic dogsMetabolism, Vol. 19, No. 4Urinary Concentration and DilutionMicropuncture studies on the influence of antidiuretic hormone on tubular fluid reabsorption in rats with hereditary hypothalamic diabetes insipidusPfl�gers Archiv European Journal of Physiology, Vol. 306, No. 2The time-course of changes in renal tissue composition during lysine vasopressin infusion in the ratPfl�gers Archiv European Journal of Physiology, Vol. 310, No. 4The Influence of the Neurohypophysial Hormones and Similar Polypeptides on the KidneysBalance between tubular flow rate and net fluid reabsorption in the proximal convolution of the rat kidneyPfl�gers Archiv European Journal of Physiology, Vol. 304, No. 1Concentration of urine in the mammalian kidneyThe American Journal of Medicine, Vol. 42, No. 5 More from this issue > Volume 212Issue 6June 1967Pages 1361-1364 Copyright & PermissionsCopyright © 1967 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1967.212.6.1361PubMed4952127History Published online 1 June 1967 Published in print 1 June 1967 Metrics