<h3>Research Objectives</h3> This study tested the hypothesis that participants with acute traumatic brain injury (TBI) randomly assigned to Resource Facilitation (RF) would demonstrate decreased levels of disability and increased levels of health related quality of life (HRQOL) when compared to patients randomly assigned to the treatment as usual (TAU) control group. Medical comorbidities and health outcomes will also be compared across the groups. This study is the first to study the efficacy of RF for health outcomes and comorbidities. <h3>Design</h3> Randomized Controlled Trial. <h3>Setting</h3> Acute Care, Post-acute Rehabilitation Hospital, and Community. <h3>Participants</h3> A total of 48 participants with TBI were recruited prior to discharge from their acute care hospital. An unequal randomization ratio was used favoring the treatment group resulting in 30 participants randomized to the treatment group and 18 participants randomized to the control group. All participants, regardless of group assignment, received follow up calls every three months to collect outcome measures. <h3>Interventions</h3> Resource Facilitation is an evidence based service navigation intervention that has been shown to improve employment rates, level of disability, and decrease unmet needs in the post-acute brain injury population. In this study, we also employed a collaborative care resource facilitation model. <h3>Main Outcome Measures</h3> Level of disability was assessed with the Mayo-Portland Adaptability Inventory-IV (MPAI-4) which is a measure developed specifically for people with TBI and provides multiple indices of recovery and level of disability. HRQOL was measured with the Patient-Reported Outcomes Measurement Information System (PROMIS) resulting in a total score as well several individual measures of HRQOL including fatigue, physical functioning, emotional health, and pain. <h3>Results</h3> Final results will include comparisons between the RF and TAU groups on level and trajectory of disability, HRQOL, medical comorbidities, and health outcomes. <h3>Conclusions</h3> Pending completion of statistical analyses. <h3>Author(s) Disclosures</h3> None.