Transmission Of Pulmonary Tuberculosis Research Articles

The Influence of Home Environment and Habits on Pulmonary Tuberculosis Transmission in Teminabuan South Sorong District

The Influence of Home Environment and Habits on Pulmonary Tuberculosis Transmission in Teminabuan South Sorong District

Comparison of microscopic and xpert MTB diagnoses of presumptive mycobacteria tuberculosis infection: retrospective analysis of routine diagnosis at Cape Coast Teaching Hospital

IntroductionTuberculosis is a global health problem that causes 1. 4 million deaths every year. It has been estimated that sputum smear-negative diagnosis but culture-positive pulmonary TB diagnosis contribute to 12.6% of pulmonary TB transmission. TB diagnosis by smear microscopy smear has a minimum detection limit (LOD) of 5,000 to 10,000 bacilli per milliliter (CFU/ml) of sputum result in missed cases and false positives. However, GeneXpert technology, with a LOD of 131–250 CFU/ml in sputum samples and its implementation is believe to facilitate early detection TB and drug-resistant TB case. Since 2013, Ghana health Service (GHS) introduce GeneXpert MTB/RIF diagnostic in all regional hospitals in Ghana, however no assessment of performance between microscopy and GeneXpert TB diagnosis cross the health facilities has been reported. The study compared the results of routine diagnoses of TB by microscopy and Xpert MTB from 2016 to 2020 at the Cape Coast Teaching Hospital (CCTH).MethodsThe study compared routine microscopic and GeneXpert TB diagnosis results at the Cape Coast Teaching Hospital (CCTH) from 2016 to 2020 retrospectively. Briefly, sputum specimens were collected into 20 mL sterile screw-capped containers for each case of suspected TB infection and processed within 24 h. The samples were decontaminated using the NALC-NaOH method with the final NaOH concentration of 1%. The supernatants were discarded after the centrifuge and the remaining pellets dissolved in 1–1.5 ml of phosphate buffer saline (PBS) and used for diagnosis. A fixed smears were Ziehl-Neelsen acid-fast stain and observed under microscope and the remainings were used for GeneXpert MTB/RIF diagnosis. The data were analyze using GraphPad Prism.Results50.11% (48.48–51.38%) were females with an odd ratio (95% CI) of 1.004 (0.944–1.069) more likely to report to the TB clinic for suspected TB diagnosis. The smear-positive cases for the first sputum were 6.6% (5.98–7.25%), and the second sputum was 6.07% (5.45–6.73%). The Xpert MTB-RIF diagnosis detected 2.93% (10/341) (1.42–5.33%) in the first and 5.44% (16/294) (3.14–8.69%) in the second smear-negative TB samples. The prevalence of Xpert MTB-RIF across smear positive showed that males had 56.87% (178/313) and 56.15% (137/244) and females had 43.13% (135/313) and 43.85% (107/244) for the first and second sputum. Also, false negative smears were 0.18% (10/5607) for smear 1 and 0.31% (16/5126) for smear 2.ConclusionIn conclusion, the study highlights the higher sensitivity of the GeneXpert assay compared to traditional smear microscopy for detecting MTB. The GeneXpert assay identified 10 and 16 positive MTB from smear 1 and smear 2 samples which were microscopic negative.

Not Your Usual Exposure: Tuberculosis Contact Investigation Related to Contaminated Bone Allograft

Background: Mycobacterium tuberculosis transmission through contaminated bone allograft product is unusual and was first described in 2021 with a second outbreak in 2023. In July 2023, Michigan Medicine conducted contact tracing for healthcare personnel (HCP), patients, and visitors following exposure to an immunocompromised patient with surgical site infection and subsequent widely disseminated tuberculosis (bacteremia, pulmonary, lymphadenopathy) following spinal fusion with bone allograft in April 2023. The patient was in the emergency department, operating room (OR), and inpatient units for 9 days prior to initiation of Airborne Precautions (AP). Methods: Michigan Medicine is a 1,107 bed academic hospital. HCP are screened for tuberculosis with interferon-gamma release assay (IGRA) testing upon hire and following tuberculosis exposure. Exposure testing includes baseline IGRA testing and follow-up testing at 10-12 weeks post exposure. Exposure criteria for this investigation was defined as sharing room airspace with the tuberculosis patient prior to initiation of airborne precautions or Central Sterile Processing Department (CSPD) staff involved with instrument decontamination without the use of a respirator. Of note, universal masking with surgical masks was not required during this time for staff and patients/visitors, with the exception of CSPD and OR staff. Contact tracing was performed by Infection Prevention and Occupational Health Services managed all test results and conversions. Results: 176 employees from perioperative care areas (n=30), CSPD (n=7), OR (n=9) and inpatient units (n=130) were IGRA tested. Five employee conversions were identified: one surgeon, one circulating OR nurse, two CSPD decontamination staff, and one respiratory therapist. At time of detection, none of the conversions had evidence of active tuberculosis. Additionally, 46 patients and visitors were tested with zero conversions. HCP compliance with IGRA testing was initially 15% before engagement from hospital and unit leadership and human resources. With intervention, employee compliance reached 100%. Conclusion: Despite standard use of surgical masks for OR and CSPD staff, aerosolization of infected bone graft material played an important role in tuberculosis transmission during surgery and instrument cleaning. Respiratory therapy practices in the ICU setting likely also increased risk for pulmonary tuberculosis transmission. Achieving 100% HCP compliance for baseline and follow-up IGRA testing is challenging and requires engagement of both unit and hospital leadership and human resources to ensure all HCP are tested.

Education on Correct Cough Ethics in An Effort to Prevent the Transmission of Pulmonary TB Disease at Galang Health Center

Pulmonary tuberculosis (TB) is a type of dangerous and infectious disease that is very important and causes serious health problems in many countries, including Indonesia. This disease is caused by the bacteria Mycobacterium tuberculosis which can attack through the air when another infected person sneezes, coughs or talks. Pulmonary TB can infect anyone, especially individuals who live in densely populated areas and have weak immune systems. Implementing correct cough etiquette is very important to prevent transmission of pulmonary TB. Correct cough etiquette includes the habit of covering your mouth and nose with a tissue or the inside of your elbow when coughing or sneezing, and washing your hands afterwards. The purpose of this education is to examine the importance of education regarding correct cough etiquette and increase knowledge of pulmonary TB sufferers at the Galang Community Health Center while also supporting the government's efforts to achieve the target of eliminating TB as a public health problem in Indonesia. The method used includes a pretest before implementing education, followed by an explanation of material regarding correct cough etiquette, and then ending with a posttest. This educational activity was carried out at the Galang Community Health Center, Deli Serdang Regency with the participation of 24 participants. Before the education was carried out, the majority of participants had poor knowledge (60%), but after the education, the majority of participants showed good knowledge (95%) and understood the principles of correct cough etiquette. It was concluded that the education participants' knowledge increased, whereas previously the majority was lacking and after the education was given the majority had good knowledge. It is recommended that we continue to apply good cough etiquette and it is hoped that there will be a significant reduction in the transmission of pulmonary TB so that it can improve the quality of public health.

NTCA Guidelines for Respiratory Isolation and Restrictions to Reduce Transmission of Pulmonary Tuberculosis in Community Settings.

NTCA Guidelines for Respiratory Isolation and Restrictions to Reduce Transmission of Pulmonary Tuberculosis in Community Settings.

Spiritual Holy Water Sites in Ethiopia: Unrecognized High-Risk Settings for Transmission of Pulmonary Tuberculosis.

Ethiopia is a high-tuberculosis (TB) burden country with 157 new cases per 100,000 people, with 23,800 TB-related deaths in 2020. In Ethiopia, TB patients have different healthcare-seeking behaviors. They frequently visit spiritual places, such as holy water sites (HWSs), to seek treatment for their illness spiritually. This study examined the prevalence of pulmonary TB (PTB) and drug susceptibility profiles of Mycobacterium tuberculosis (MTB) isolates among spiritual HWS attendees in Northwest Ethiopia. A cross-sectional study was conducted from June 2019 to March 2020. Sputum samples were collected, processed, and cultured using Löwenstein-Jensen (LJ) culture medium. Second-generation line probe assays (LPAs), GenoType®MTBDRplus VER2.0 and GenoType®MTBDRsl VER2.0, were used to detect anti-TB drug-resistant isolates. STATA 17 was utilized to perform descriptive statistics, bivariate, and multivariate regression analyses. Of 560 PTB-symptomatic participants, 21.8% ((95% confidence interval (95 CI): 18.4-25.2%)) were culture-positive, resulting in a point prevalence of 1,183/100,000 attendees. Amongst HWS attendees, culture-positive TB occurred most commonly in persons 18-33 years of age (28.5% (95 CI 23.4-34.3%)). Other participant characteristics significantly associated with culture-positive PTB were as follows: rural residents (adjusted odds ratio (aOR) 2.65; 95 CI 1.38-5.10), married participants (aOR 2.43; 95 CI 1.28-4.63), family members >5 per household (aOR 1.84; 95 CI 1.04-3.24), and sharing living space (aOR 10.57; 95 CI 3.60-31.13). Also, among 438 participants followed for 12 months after showing negative TB culture results while at the HWS, 6.8% (95 CI 4.4-9.4%) developed or contracted culture-positive TB post-residency at the HWSs. Of the 122 tested isolates, 20 (16.4%) were isoniazid (INH) and/or rifampicin (RIF) resistant. Multidrug-resistant (MDR) TB was detected in 15 cases (12.3%), five of which were fluoroquinolones (FLQs) resistant. The findings from this study should raise a concern about HWSs as potential high-risk settings for TB transmission. It is recommended that appropriate control measures be instituted that include compulsory TB testing and tightened infection control at HWSs, where an increased risk exists for transmission of TB.

Relationship between nutritional status and the incidence of tuberculosis transmission in the family in Batusumur Village, Manonjaya Subdistrict Tasikmalaya Regency

Tuberculosis is the second infectious disease that causes the most deaths in the world according to WHO. Indonesia is a high TB burden country which currently ranks third in the world, with an incidence of 845.000 or 320/100.000 population with a mortality rate of 98.000 or 40/100.000 population and 3,6/100.000 TB-HIV population. The risk factor that can cause tuberculosis disease is malnutrition. The aim of the study was to determine the relationship between nutritional status and the incidence of tuberculosis transmission in the family. The purpose of this study was to determine the relationship between nutritional status and the incidence of tuberculosis. The research design used cross sectional study. The research was conducted in December 2023 in Batusumur Village, Manonjaya District, Tasikmalaya Regency. The research sample was 39 respondents of tuberculosis patients. Inclusion criteria: patients actively communicate and are easy to talk to, patients live with family members and are still in the initial phase of treatment in the first 2 months. The independent variable was nutritional status. The dependent variable was the incidence of pulmonary tuberculosis transmission in family members. The instrument was an observation sheet. Data were analyzed by chi square test using SPSS. This research applies the principles of confidentiality, useful information and scientific development. The results showed that there was a relationship between nutritional status (p=0,026) and the incidence of tuberculosis transmission in the family. The conclusion is that there is a relationship between nutritional status and the incidence of tuberculosis. Tuberculosis patients and their families can make preventive efforts to prevent tuberculosis transmission.

Education On Prevention Of Pulmonary Tuberculosis Transmission Using TikTok Media At The Sukorejo Health Centre

The incidence of pulmonary tuberculosis (pulmonary TB) continues to increase every year, one of the contributing factors is the lack of public knowledge about pulmonary tuberculosis so that there are still many people who are not healthy. The purpose of this study was to describe family knowledge about preventing pulmonary tuberculosis transmission using TikTok media at the Sukorejo Health Center. This research uses a descriptive method. The population in this study were all families accompanying pulmonary tuberculosis patients who were still registered and actively seeking treatment at the Sukorejo Health Center from January to April 2023, totaling 20 people. A sample size of 20 accompanying families of pulmonary tuberculosis patients was taken using total sampling technique. Data collection used an instrument in the form of a questionnaire. The results of the study were: family knowledge about preventing the transmission of pulmonary tuberculosis using TikTok media as much as 80% in the good category, 20% in the enough category. Not all families can understand the prevention of pulmonary tuberculosis transmission using TikTok media, so a holistic approach is needed. Various parties need to work together to increase family understanding about preventing the transmission of pulmonary tuberculosis

Determinasi Faktor Lingkungan Mikro Terhadap Sebaran Kasus Tuberkulosis Paru di Kota Dumai: Studi cross-sectional

Mycobacterium tuberculosis is the second leading cause of death worldwide, after COVID-19. This study investigated the prevalence and microenvironmental determinants of pulmonary TB in Dumai City, focusing on the urban areas. Using a cross-sectional approach in three areas with high, medium, and low rates of pulmonary TB, this study identified the ventilation, lighting, humidity, floor and wall material type, and occupancy density variables that influence pulmonary TB transmission. The results showed that inadequate microenvironmental conditions significantly contributed to the spread of pulmonary TB. Effective management of these microenvironmental risk factors is essential as a basis for public health interventions to reduce the TB prevalence in Dumai City.

Modelling of tuberculosis dynamics incorporating indirect transmission of contaminated environment and infectivity of smear-negative individuals: A case study for Xinjiang, China

Xinjiang has been one of the high incidence areas of pulmonary tuberculosis (PTB) in China. Besides being infected by direct contacting with active PTB individuals (direct infection), the susceptible would be infected because of the exposure to the environment contaminated by Mycobacterium tuberculosis (indirect infection). Active PTB individuals include not only the smear-positive PTB (PTB+) but also the smear-negative PTB (PTB–) who are infectious due to their ability to release tiny Mycobacterium tuberculosis particles even in the absence of visible Mycobacterium tuberculosis in sputum. By taking account of direct/indirect infection and the difference between PTB+ and PTB– individuals in transmission capability, a periodic dynamical PTB transmission model is proposed. The model is fitted to the newly monthly PTB+ and PTB– cases in Xinjiang from 2008 to 2017 by Markov Chain Monte Carlo algorithm. Moreover, global sensitivity analysis is constructed to address the uncertainty of some key parameters by using Latin hypercube sampling and partial rank correlation coefficient methods. Basic reproduction number R0 for PTB transmission in Xinjiang is estimated to be 2.447 (95% CrI:(1.203, 3.844)), indicating that PTB has been prevalent in Xinjiang over the study period. Our results suggest that reducing the direct/indirect transmission rates, early screening, isolating and treating the latent, PTB+ and PTB– individuals, and enhancing the clearance of Mycobacterium tuberculosis in the environment could more effectively control PTB transmission in Xinjiang. The model fits the reported PTB data well and achieves acceptable prediction accuracy. We believe that our model can provide heuristic support for controlling PTB transmission in Xinjiang.

EDUKASI PERILAKU PENCEGAHAN PENYAKIT TUBERKULOSIS DI RS. WOODWARD

Tuberculosis (TB or TBC) is an infectious disease caused by the germ Mycobacterium tuberculosis. These germs usually enter the human body through breathing air into the lungs, then these germs can spread from the lungs to other parts of the body through the circulatory system, lymphatic system, through the respiratory tract (bronchus) or spread directly to other parts of the body.This community service aims to increase public knowledge and awareness in preventing the transmission of pulmonary tuberculosis. The counseling method uses leaflet media and will be carried out on December 9 2023 at the hospital. Woodward, Palu City. As a result of community service, the material presented was able to increase their knowledge as evidenced by the evaluation session, the community was asked questions and on average the community was able to answer correctly according to the material provided. Conclusion: Community service activities have been carried out. It is hoped that the excellent presence and enthusiasm of the residents can prevent the occurrence of Tuberculosis.

Modeling the effects of vaccine efficacy and rate of vaccination on the transmission of pulmonary tuberculosis

Numerous prevention intervention strategies have been developed to curtail the spread of pulmonary tuberculosis to susceptible populations. However, pulmonary tuberculosis continues to claim many lives worldwide. In this paper, a deterministic mathematical model incorporating an asymptomatic infectious population, considering vaccine efficacy, and vaccination rate, has been formulated. The model includes asymptomatic infectious individuals since they spread infections incessantly to susceptible populations without being noticed, thus contributing to the high transmission rate. Sensitivity and numerical analysis have been conducted to investigate the impact of varying vaccine efficacy and vaccination rates on the transmission of pulmonary tuberculosis infections from the asymptomatic infectious population. The sensitivity and numerical results show that an increase in vaccine efficacy reduces the asymptomatic infectious population and subsequently lowers the transmission rate of infections. Moreover, an increase in vaccine efficacy was shown to reduce the control reproduction number due to asymptomatic infectious individuals, thereby decreasing the transmission of pulmonary tuberculosis to susceptible populations. Further results indicate that an increase in vaccination rate reduces the control reproduction number due to asymptomatic infectious individuals, consequently lowering the rate of infection transmission. These findings emphasize the need to develop a vaccine of higher efficacy to reduce infection transmission to susceptible populations by the asymptomatic infectious individuals. Additionally, the results underscore the importance of increasing vaccination rates to eradicate pulmonary tuberculosis from the population.

PENYULUHAN TUBERKULOSIS PARU KEPADA MASYARAKAT LINGKUNGAN HAMPARAN PERAK KECAMATAN DELI SERDANG

The aim of community service activities is to implement community service in implementing the Tri Dharma of higher education as well as contributing ideas and transferring knowledge to mothers, fathers, children and youth. This service activity was carried out on March 24 2022, with the material Lung Tuberculosis. This topic is really needed in order to provide information and knowledge about Pulmonary Tuberculosis, starting from how to prevent and treat Pulmonary TB patients. This topic was deliberately chosen considering that currently TB is still the biggest health problem in the world, apart from that, our country, Indonesia, has the second highest rate of TB. Therefore, the role of medical personnel is very important in providing education to the public to behave in a clean manner at home and around the home environment, where this activity aims to reduce the risk of transmission and infection of Pulmonary Tuberculosis.

Peran Preceptor terhadap Ansietas Mahasiswa Praktik Klinik Terkait Penularan Penyakit Tuberkulosis Paru di Rumah Sakit

This study aims to determine the relationship between the role of the preceptor and the anxiety of clinical practice students in hospitals. This research method is quantitative, using a cross-sectional study design approach. The results of the study showed that there was a significant relationship between the role of preceptor, knowledge, and students' level of anxiety regarding TB transmission in hospitals with a p-value <0.05. In conclusion, there is a relationship between the role of the preceptor and the fear of clinical practice students in hospitals regarding the transmission of pulmonary TB.
 Keywords: Anxiety; Nursing, Student, Perceptor, Tuberculosis

Preventive behaviors toward transmission of pulmonary tuberculosis

Introduction: Indonesia was ranked as the second largest country in the world as a person with pulmonary Tuberculosis (TB) after India. This shows that there needs to be action to reduce the transmission of pulmonary TB, especially in family members who are in the same house. The purpose of this study was to identify factors related to preventive measures for the transmission of pulmonary tb in the city of Surabaya. Methods: Quantitative research design with a cross-sectional approach, respondents were pulmonary TB sufferers aged > 15 years old for treatment at the East Perak Health Center and Jagir Health Center was totaling 262 respondents. Research variables include gender, age, education, patient category, drug ingestion supervisor, regularity of drug ingestion, search for treatment, knowledge, attitudes, and behaviors towards TB disease are obtained through the dissemination of questionnaires. Furthermore, data processing and statistical tests through (X2) chi square and linear regression. Results: The results showed that gender, age, education, patient category, drug ingestion supervisor, regularity of drug ingestion, search for treatment, knowledge, attitudes, and behaviors towards TB disease significantly affect the prevention of pulmonary Tb transmission. Conclusion: Pulmonary TB patients and family members need to remind each other to behave clean and healthy to prevent the transmission of pulmonary TB. It is very necessary to visit regularly from health services or health workers, to provide education about clean and healthy living behaviors.

Spatial-temporal patterns and influencing factors for pulmonary tuberculosis transmission in China: an analysis based on 15 years of surveillance data.

Profiting from a series of anti-tuberculosis programs in China, the number of tuberculosis (TB) cases has diminished dramatically in the past decades. However, long-term spatial-temporal variations, regional trends of prevalence, and mechanisms of determinant factors remain unclear. Age-period-cohort analysis and Bayesian space-time hierarchy statistics were conducted to identify high-risk populations and areas in mainland China, and the geographical detector model was used to evaluate the important drivers of the disease. The prevalence of pulmonary TB has declined from 73.3/100,000 in 2004 to 55.45/100,000 in 2018. A bimodal distribution was found in age groups, and the birth cohorts before 1978 had relative higher risk. The high-risk areas were mainly distributed in western China and south-central China, and several provinces in eastern China showed a potential increasing trend, including Beijing, Shanghai, Liaoning, and Guangdong province. The index of night light (Q = 0.46), the population density (Q = 0.41), PM10 (Q = 0.38), urbanization rate (Q = 0.32), and PM 2.5 (Q = 0.31) contributed substantially to the spatial distribution of pulmonary tuberculosis. The identifications of epidemic patterns, high-risk areas and influence factors would help design targeted intervention measures to achieve milestones of the end TB strategy.

Analisis Faktor Risiko TB paru Anak yang Tinggal Serumah dengan Penderita TB paru Dewasa

Pulmonary tuberculosis (TB) is still a major public health problem in Indonesia. Based on the Household Health Survey (SKRT) results tuberculosis is the number one respiratory disease and infectious disease. Tuberculosis in children causes growth disorders and even death. If pulmonary tuberculosis in a child is not treated immediately, it can quickly develop into parenchymal or tubercular pneumonia, milliary tuberculosis, bone tuberculosis (scrofuloderma), joint tuberculosis, abdominal tuberculosis, and even meningitis. This study used a case-control design with analytical observation. Children who were exposed to and lived in the same household with adult pulmonary tuberculosis patients as many as 90 adults participated in the study. The case sample consisted of children aged 0-15 years who were diagnosed with Pulmonary TB by doctors at the Wania Health Center, Mimika Regency. The case sample size was 30 respondents and the control sample was 30 respondents. The free variables in this study were parental knowledge, BCG vaccination history, child nutritional status, occupancy density, the behavior of TB sufferers at home, and length of contact. Data were analyzed using univariate analysis, bivariate analysis, and multivariate analysis (multiple logistic regression). The results of the study analysis showed that the factors that influence the incidence of tuberculosis in children are parental knowledge (p = 0.001), BCG vaccination history (p = 0.001), and the behavior of adult tuberculosis sufferers in the household (p = 0.000) The conclusion of the study was that the behavior of adult pulmonary tuberculosis patients who lived in the same house with children was most influential in the transmission of pulmonary tuberculosis in children who lived in the same household as adult pulmonary tuberculosis patients at the Health Centre of Wania, Mimika District.

Pemberdayaan Warga Binaan dalam Upaya Pencegahan TB Paru di Lapas Perempuan Kelas II A Pontianak

Pulmonary Tuberculosis is a direct infectious disease caused by the tuberculosis germ (Mycobacterium tuberculosis) which is transmitted through the air (droplet nuclei) when a patient coughs and splashes of saliva containing the bacteria are inhaled by another person while breathing. The risk factors for the incidence of pulmonary TB are, occupancy density, lack of ventilation, poor lighting, access to inadequate facilities. The problems that exist in partners are the lack of counseling activities, especially related to health education on the prevention of pulmonary TB, the condition of densely populated prisons, inadequate ventilation and inadequate lighting are risk factors for the development of pulmonary TB. The first step is to collect pre-test data before being given health information on TB prevention. Furthermore, health education was given about prevention of pulmonary TB to the inmates. At the evaluation stage, post-test data were collected. Based on the results of community service activities with the target of assisted residents in the Pontianak class II women's correctional prison, it went well. Participants can participate in activities from start to finish with enthusiasm. After participating in this activity, it was found that there was an increase in knowledge in efforts to prevent pulmonary TB in prisons. It is hoped that the prison can increase health education activities, especially pulmonary TB, this is necessary to prevent transmission of pulmonary TB in prisons.

Duration of Contact on Pulmonary Tb Transmission: Case Study - Control

The Ambon City Health Office, through the Prevention and Control of Infectious Diseases, pointed out that the number of new TB cases in Ambon City in the last three years has tended to increase, where in 2020 the number of cases was 716, in 2021 there were 961 and in 2022 there were 1,296 sufferers. with the number of deaths of 32 people in 2020, in 2022 and 2023 each of 23 people. This study used an analytic observational study with a case control study design, designed to determine the risk and the effect of exposure duration on pulmonary TB transmission with a total sample of 72, bivariate analysis using the chi square test and calculating the odds ratio (OR). multivariate analysis using binary logistic regression test. The results of the study found that close contact is a risk factor for TB transmission with OR = 4.857; contact time is a risk factor for TB transmission with OR = 6.143; and length of contact are risk factors for TB transmission with OR = 5.857. The binary logistic regression equation shows that someone who lives in the same house with a patient with pulmonary tuberculosis, exposure time > 8 hours/day and contact duration > 6 months, has a probability of suffering from pulmonary TB by 30% compared to someone without risk factors. In conclusion, the closeness of contact, contact time and duration of contact are risk factors for pulmonary TB transmission.

Implementation of the Family Health Promotion Model (FHPM) on Family Commitment in TB Transmission Preventive Action among the Heads of Familiesof TB Patients: A Structural Model

Tuberculosis (TB) transmission prevention centering on family is an effective strategy to suppress the emergence of new clusters of pulmonary TB transmission. The commitment of family heads and several factors are related to this action. This study was conducted to identify, examine, and analyze the determinants of family commitment in preventing the transmission of pulmonary TB. This study applied a quantitative cross-sectional approach to 170 family heads of pulmonary TB patients using proportionate simple random sampling. The family health promotion model (FHPM) was used to analyze family commitment determinants in preventing TB transmission. Data were collected using a questionnaire. SEM analysis was utilized to determine the paths and the relationship between family function, perception of the disease transmission risk, as well as family support, and commitment to action to prevent TB transmission. This study recorded that 50.6% of respondents were male with an average age of 46.75 ± 46 and an age range of 36-55 years, 53% had a high school education; 25.9% were self-employed; had an average decent living need of 1.93 ± 0.85, 75.3% had nuclear family, and 47.1% were from patriarchal family. Model fit was achieved in the structural equation (Chi-square (χ2) = 173.44; df = 71, RMSEA = 0.072≤ 0.08; GFI = 0.90≥ 0.90; RMR = 0.019≤ 0.05; NFI = 0.98≥ 0.90; CFI = 0.99≥ 0.90; TLI = 0.98≥ 0.95; IFI = 0.99≥ 0.90; PGFI = 0.59; PNFI = 0,76). All dimensions and item scales are significantly related to their respective latent constructs. All factors forming the FHPM framework have a significant positive direct effect between latent variables. Factors from the FHPM framework significantly (family function t = 8.74, perception t = 4.46, and family support t = 7.37) have an influence on commitment to action to prevent pulmonary TB transmission. Family function is the most powerful factor explaining commitment to preventive action. This study reveals the paths and influences of family function, perception, and support on a commitment to prevent pulmonary TB transmission through structural model analysis.