This study aims to analyze the superior artery bloodflow in healthy premature neonates with birth weightbetween 1,000 g and 1,500 g, on the first and seventhdays of live.It is a prospective cohort study, including 15 prema-ture neonates with mean weight of 1,243g ± 173.6 (ran-ging from 1,000 to 1,495 g). Exclusion criteria were:unstable hemodynamic conditions; assisted ventilationwith high parameters; large deformations or clinicalsyndromes; feeding intolerance; necrotizing enteroco-litis; and conditions those alter the mesenteric flow:phototherapy, umbilical catheters, patient ductus arte-riosus and sepsis.The Doppler velocimetric examination was done bya 8 MHz imaging transducer, and the pulsed color Dop-pler readings were obtained by sonographic waves at 4MHz. The neonate was kept in a supine position, withthe transducer positioned in the epigastric region,immediately below the xyphoid appendix, obtainingtwo dimensional images of the celiac trunk and of thesuperior mesenteric artery, a few millimeters after itsemergence from the aorta in the sagital plane.The flux measurements were obtained in the longitudi-nal direction of the vessel and at an isonation angle betwe-en 0 and 20 degrees. The blood flow curves were recordedafter a sequence of five stable measurements, with respectto the quality of the waves, and their audible characteris-tics. The following measurements were obtained: PeakSystolic Velocity (PSV), End Diastolic Velocity (EDV),Resistance Index (RI), and Pulsatility Index (PI).The values obtained were expressed in means and stan-dard deviations. The measurements were done prior tofeeding (up to 30 minutes) and after feeding (between 15and 60 minutes). The measurements were done on the firstday (between the 6th and the 24th hours of life), and on the7th day of life. The comparison of means and standarddeviations was carried out by ANOVA.Table I lists the values of RI, PI, PVS, and EDV,prior and after feeding, on the first and 7th days of life,in means and standard deviations.In conclusion, these studied neonates showed a signifi-cant evolution of the blood flow of superior mesentericartery on the 7th day of life, represented by the Peak Sys-tolic Velocity and the End Diastolic Velocity improve,and a better vasodilatation response after feeding.These results suggest for the Doppler velocimetry asa specific evaluation method for feeding introductionand progression, in order to reduce the prevalence ofgastrointestinal inflammatory diseases in neonates, andto improve the neonatal survive