The article presents the results of the study of the properties of the nervous system, the speed of simple and complex reactions, short-term visual memory of first-person shooter CS: GO and multiplayer battle arena DOTA 2. Relevance of the description of individual typological personality traits of participants relationships with indicators of gaming activity is associated with the possibility of creating psychodiagnostic tools to determine the propensity to certain disciplines of e-sports, the development of psychological foundations to improve the effectiveness of training and competitive activities of e-sportsmen based on their individuality, prevention of psychological risks of e-sports. Purpose: to identify and analyze individual sensorimotor abilities and properties of the nervous system of players who prefer different e-sports genres. Research methods: theoretical analysis of literature sources, pedagogical testing, methods of mathematical statistics. The study involved e-sports players Counter-Strike: Global Offensive (n = 18) and DOTA 2 (n = 10) aged 18-20 years. According to the playing experience, the number of playing hours per week, the regularity of participation in competitions and their level, these players were classified as amateurs. It is established that the main factors determining the effectiveness of e-sports are sensorimotor coordination, nervous system properties, cognitive properties, technical and tactical skills, social communication skills and more. In games of both genres, the speed of simple and complex reactions has been found to be important, but it is most effective in combination with a high level of technical and tactical training. Analysis of the results of the study showed that players in different e-sports disciplines have some differences in sensorimotor abilities, but at the level of amateurs guilt does not have a significant difference. At the same time, they have significant differences in the type of nervous system.