Objective: The present study examined the association of anxiety- and anger-related components to depressive symptomatology for men and women. Methods: The study relied on a cross-sectional design. of 2,054 Japanese workers affiliated with two occupational settings, complete responses on measures for depression, anxiety, and anger, were obtained from 1,862 workers (90.7%: 1,521 men, 341 women). A stepwise regression analysis was executed by gender and age group. Results: Stepwise regression analysis revealed that main components were almost the same for both genders, i.e., trait anxiety, state anger and anger suppression. However, the explaining variances of anger were much larger for men, whereas those of state anxiety were larger for women. Anger expression outward was selected for men, but not for women. Conclusions: Depressive symptomatology was largely explained by trait anxiety, state anger, and anger expression style. For men, state anger and either expression of feelings of anger inward or outward were exacerbating their depression as compared to women. This could explain in part the gender differences in depression.