Trains Of Stimuli Research Articles

Perceptual learning across saccades: Feature but not location specific

Perceptual learning is the ability to enhance perception through practice. The hallmark of perceptual learning is its specificity for the trained location and stimulus features, such as orientation. For example, training in discriminating a grating's orientation improves performance only at the trained location but not in other untrained locations. Perceptual learning has mostly been studied using stimuli presented briefly while observers maintained gaze at one location. However, in everyday life, stimuli are actively explored through eye movements, which results in successive projections of the same stimulus at different retinal locations. Here, we studied perceptual learning of orientation discrimination across saccades. Observers were trained to saccade to a peripheral grating and to discriminate its orientation change that occurred during the saccade. The results showed that training led to transsaccadic perceptual learning (TPL) and performance improvements which did not generalize to an untrained orientation. Remarkably, however, for the trained orientation, we found a complete transfer of TPL to the untrained location in the opposite hemifield suggesting high flexibility of reference frame encoding in TPL. Three control experiments in which participants were trained without saccades did not show such transfer, confirming that the location transfer was contingent upon eye movements. Moreover, performance at the trained location, but not at the untrained location, was also improved in an untrained fixation task. Our results suggest that TPL has both, a location-specific component that occurs before the eye movement and a saccade-related component that involves location generalization.

The Effects of a Supramaximal Intermittent Training Program on Aerobic and Anaerobic Running Measures in Junior Male Soccer Players.

This study investigated the effectiveness of supplementing regular preseason soccer training with a supramaximal intermittent shuttle-run training (ISRT) model prescribed from Carminatti's Test peak speed (PST-CAR) in aerobic performance-related indices and sprinting speed in male junior soccer players. Twenty-three national-level soccer players (mean ± SD; age 18.07 ± 0.9 y, body height 1.76 ± 0.65 m, body mass 71.9 ± 8.7 kg) were assigned to either an experimental group (EG; n = 13) performing ISRT + soccer training or a control group (CG; n = 10) that followed regular preseason soccer training alone. The following tests were applied before and after the eight-week training intervention: (i) incremental treadmill tests (VO2max and lactate minimum speed - LMS); (ii) linear 30-m sprint test and Carminatti's Test (PST-CAR). Results indicated larger gains for the EG in LMS (Δ = 9.53% vs. 2.82%) and PST-CAR (Δ = 5.50% vs. 2.10%) than in the CG. Furthermore, changes in VO2max produced higher effect size (d) values for the EG (Δ = 6.67%; d = 0.59) than the CG (Δ = 1.88%; d = 0.18). Both groups improved (p = 0.002) their flying 20-m sprint speed (EG: Δ = 1.01%; CG: Δ = 1.56%). However, small decreases were observed for 10-m sprint speed in the CG (Δ = -2.19%; d = -0.44), while only trivial changes were noticed for the EG (Δ = -0.50%; d = -0.16). Our data support that additional supramaximal ISRT is an effective training stimulus to enhance aerobic performance-related indices and promote small improvements in maximal running speed without impairing the soccer players' acceleration capacity. This study also shows that PST-CAR can be useful for individualizing running intensity in supramaximal ISRT modes.

Effects of detraining on left ventricular mass in endurance-trained individuals: a systematic review and meta-analysis.

Detraining refers to a loss of training adaptations resulting from reductions in training stimulus due to illness, injury, or active recovery breaks in a training cycle and is associated with a reduction in left ventricular mass (LVM). The purpose of this study was to conduct a systematic review and meta-analysis to determine the influence of detraining on LVM in endurance-trained, healthy individuals. Using electronic databases (e.g. EMBASE and MEDLINE), a literature search was performed looking for prospective detraining studies in humans. Inclusion criteria were adults, endurance-trained individuals with no known chronic disease, detraining intervention >1 week, and pre- and post-detraining LVM reported. A pooled statistic for random effects was used to assess changes in LVM with detraining. Fifteen investigations (19 analyses) with a total of 196 participants (ages 18-55 years, 15% female) met inclusion criteria, with detraining ranging between 1.4 and 15 weeks. The meta-analysis revealed a significant reduction in LVM with detraining (standardized mean difference = -0.586; 95% confidence interval = -0.817, -0.355; P < 0.001). Independently, length of detraining was not correlated with the change in LVM. However, a meta-regression model revealed length of the detraining, when training status was accounted for, was associated with the reduction of LVM (Q = 15.20, df = 3, P = 0.0017). Highly trained/elite athletes had greater reductions in LVM compared with recreational and newly trained individuals (P < 0.01). Limitations included relatively few female participants and inconsistent reporting of intervention details. In summary, LVM is reduced following detraining of one week or more. Further research may provide a greater understanding of the effects of sex, age, and type of detraining on changes in LVM in endurance-trained individuals.

Trait and State Anxiety Effects on Mismatch Negativity and Sensory Gating Event-Related Potentials.

We used the auditory roving oddball to investigate whether individual differences in self-reported anxiety influence event-related potential (ERP) activity related to sensory gating and mismatch negativity (MMN). The state-trait anxiety inventory (STAI) was used to assess the effects of anxiety on the ERPs for auditory change detection and information filtering in a sample of thirty-six healthy participants. The roving oddball paradigm involves presentation of stimulus trains of auditory tones with certain frequencies followed by trains of tones with different frequencies. Enhanced negative mid-latency response (130-230 ms post-stimulus) was marked at the deviant (first tone) and the standard (six or more repetitions) tone at Fz, indicating successful mismatch negativity (MMN). In turn, the first and second tone in a stimulus train were subject to sensory gating at the Cz electrode site as a response to the second stimulus was suppressed at an earlier latency (40-80 ms). We used partial correlations and analyses of covariance to investigate the influence of state and trait anxiety on these two processes. Higher trait anxiety exhibited enhanced MMN amplitude (more negative) (F(1,33) = 14.259, p = 6.323 × 10-6, ηp2 = 0.302), whereas state anxiety reduced sensory gating (F(1,30) = 13.117, p = 0.001, ηp2 = 0.304). Our findings suggest that high trait-anxious participants demonstrate hypervigilant change detection to deviant tones that appear more salient, whereas increased state anxiety associates with failure to filter out irrelevant stimuli.

Effects of 56-Kilogram Kettlebell Swing Endpoint on Total Body Mechanics.

Ross, JA, Keogh, JWL, Lorenzen, C, and Lake, J. Effects of 56-kilogram kettlebell swing endpoint on total body mechanics. J Strength Cond Res 37(12): 2333-2338, 2023-In the past 2 decades, kettlebell training popularity has increased and the range of kettlebells has expanded to 2-92 kg. However, commercially available kettlebells above 56 kg have 12 kg increments, so alternatives to load are required to provide a suitable way of increasing training stimulus until the athlete is strong enough for a load increase. This study aimed to determine the differences in the force plate-derived biomechanical characteristics of heavy kettlebell swings to 3 different heights, as altering the height of the kettlebell swing may be one way to alter the mechanical demands with the same kettlebell mass. Fifteen resistance-trained men performed the kettlebell swing to acromion process height (AH), acromion process height + 20% (AH+20), and acromion process height-20% (AH-20). Swing height significantly affected vertical braking and propulsion phase net impulse and displacement, vertical braking velocity, and braking and propulsion work but not braking and propulsion duration. Altering kettlebell swing trajectory endpoint is a method to regress/progress the demands of kettlebell training. Coaches may be able to alter the acute demands and likely chronic adaptations of kettlebell training by prescribing different swing heights and kettlebell masses to their athletes.

How Does the Jumping Performance Differs between Acrobatic and Rhythmic Gymnasts?

An increased jumping performance is key for gymnastics competition routines. Rhythmic gymnasts (RGs) use the jump as one of the main body elements. In Acrobatic Gymnastics (ACRO), top gymnasts must coordinate their jumps with the impulse provided by base gymnast(s). It is expected that the gymnasts’ discipline and role played impact their jumping skill. This work aims to investigate how the jumping performance differs between ACRO gymnasts and RGs, focusing on the Force–Velocity (F-V) profile mechanical variables. Gymnasts were divided in three groups: ACRO tops (n = 10, 13.89 (3.62) median (interquartile interval) years old), ACRO bases (n = 18, 18.24 (4.41) years old) and RGs (n = 15, 12.00 (3.00) years old). The F-V profile during countermovement jump and its mechanical variables were evaluated using MyJump2. A training background survey and anthropometric assessments were conducted. The significance level was set at p ≤ 0.05. Group comparisons showed that ACRO bases jump higher than ACRO tops and RGs, present a higher maximal force than RGs and a more balanced F-V profile, while RGs present high force deficits. Coaches can use this data to develop interventions that optimize the training stimulus to different gymnastics disciplines considering the individual characteristics and adaptability of each gymnast.

Spatial separation between two sounds affects the timing of action potentials elicited by the sounds in the rat's auditory midbrain neurons

Timing of action potentials (i.e., spikes) elicited by sounds is used by auditory neurons to encode and process acoustic information. In the presence of multiple sounds, the timing of sound-driven spikes is dependent on the temporal, spectral, and spatial relationships among the sounds. We used two tone bursts with different frequencies to form a train of stimuli that were presented at a random odor and a constant rate. Such a train was used to mimic two competing sounds that occurred at the same (50%) probability or a novel sound (i.e., a low probability oddball sound) that was interleaved with a frequently occurring background sound (i.e., a high probability standard sound). We used the rat as an animal model to study how the spatial relationship between two sounds affected the timing of spikes elicited by the sounds in individual neurons in the auditory midbrain. Results indicate that a lower probability of sound presentation led to a higher temporal precision of the timing of the first spike elicited by the sound and the timing could be affected by a spatial separation between two sounds. These results are important for understanding neural mechanisms responsible for hearing in a natural acoustic environment.

Individual Control Strategies in Training: Myoelectric activity and recruitment strategies in the co-contraction training

BACKGROUND: The literature in motor control has abundant evidence on within-/between-person variability when it comes to control strategies in several behaviors - which largely influences intervention outcomes. Despite being an intervention itself, strength training paradigms are yet to be analyzed beyond the average behavior. Based on myoelectric activity (EMG) analyses, this study emerges as a descriptive analysis on how the co-contraction training paradigm provides stimuli for strength training of knee extensors and flexors. AIM: Considering the potential large interindividual variability in muscle activation patterns during resistance training, we explored the co-contraction paradigm considering the individual characteristics. METHOD: Ten active male adults participated in two days of co-contraction training paradigm with their EMG activity collected (sartorius, biceps femoris long and short heads, semitendinosus, semimembranosus, rectus femoris, vastus lateralis and medialis and tensor fascia-latae). RESULTS: On average, participants recruit 36% of their maximum EMG amplitude, decay 0.41% per repetition but increase 7.45% between sessions. The training stimulated similarly the knee flexors and extensors EMG ratio of all participants. However, participants demonstrated different average muscle recruitment patterns with few individuals modifying, largely, their recruitment over repetitions/days. Between and within-variability in recruitment pattern was maintained throughout repetitions and days. CONCLUSION: Thus, the co-contraction training demonstrated sufficient muscle activation to be employed and evoked similar muscular recruitment between agonists and antagonists. To the best of our knowledge, this is a pioneer study encompassing the complexity of movement control in evaluating a strength training protocol.

Comparison of Motor Evoked Potentials Neuromonitoring Following Pre- and Postoperative Transcranial Magnetic Stimulation and Intraoperative Electrical Stimulation in Patients Undergoing Surgical Correction of Idiopathic Scoliosis.

The relationships between the results of pre- and intraoperative motor evoked potential recordings during neuromonitoring and whether idiopathic scoliosis (IS) surgical correction improves the spinal efferent transmission have not been specified in detail. This study aims to compare the results of surface-recorded electromyography (EMG), electroneurography (ENG, M, and F-waves), and especially motor evoked potential (MEP) recordings from tibialis anterior muscle (TA) bilaterally in 353 girls with right idiopathic scoliosis (types 1-3 according to Lenke classification). It has not yet been documented whether the results of MEP recordings induced by transcranial single magnetic stimulus (TMS, pre- and postoperatively) and trains of electrical stimuli (TES; intraoperatively in T0-before surgery, T1-after pedicle screws implantation, and T2-after scoliosis curvature distraction and derotation following two-rod implantation) can be compared for diagnostic verification of the improvement of spinal cord neural transmission. We attempted to determine whether the constant level of optimal anesthesia during certain surgical steps of scoliosis treatment affects the parameters of MEPs recorded during neuromonitoring procedures. No neurological deficits have been observed postoperatively. The values of amplitudes but not latencies in MEP recordings evoked with TMS in IS patients compared before and after surgery indicated a slight improvement in efferent neural transmission. The results of all neurophysiological studies in IS patients were significantly asymmetrical and recorded worse on the concave side, suggesting greater neurological motor deficits at p = 0.04. The surgeries brought significant improvement (p = 0.04) in the parameters of amplitudes of sEMG recordings; however, the consequences of abnormalities in the activity of TA motor units were still reflected. ENG study results showed the symptoms of the axonal-type injury in peroneal motor fibers improving only on the concave side at p = 0.04, in parallel with F-wave parameters, which suggests that derotation and distraction might result in restoring the proper relations of the lumbar ventral roots in the spinal central canal, resembling their decompression. There were no significant differences detected in the amplitudes or latencies of MEPs induced with TMS or TES when comparing the parameters recorded preoperatively and intraoperatively in T0. The amplitudes of TES-evoked MEPs increased gradually at p = 0.04 in the subsequent periods (T1 and T2) of observation. A reduction in MEP latency at p = 0.05 was observed only at the end of the IS surgery. Studies on the possible connections between the level of anesthesia fluctuations and the required TMS stimulus strength, as well as the MEP amplitude changes measured in T0-T2, revealed a lack of relationships. These might not be the factors influencing the efferent transmission in spinal pathways beside the surgical procedures. Pre- (TMS-evoked) and intraoperative (TES-evoked) recordings are reliable for evaluating the patient's neurological status before and during surgical scoliosis correction procedures. An increase in MEP amplitude parameters recorded on both sides after scoliosis surgery proves the immediate improvement of the total efferent spinal cord transmission. Considering comparative pre- and postoperative sEMG and ENG recordings, it can be concluded that surgeries might directly result in additional lumbar ventral root decompression. We can conclude that MEP parameter changes are determined by the surgery procedures during neuromonitoring, not the anesthesia conditions if they are kept stable, which influences a decrease in the number of false-positive neuromonitoring warnings.

An annotation-independent algorithm based on electrogram characteristics to guide the identification of ventricular tachycardia isthmuses in patients with structural heart disease.

Criteria such as electrograms voltage or late potentials have been largely utilized in the past to help identify areas of substrate maps that are within the ventricular tachycardia (VT) isthmus; yet their specificity and positive predictive value are quite low. The Lumipoint fractionation tool of the Rhythmia system illuminates regions with fractionated electrograms irrespective of their timing and annotation. We aimed to ascertain whether the use of this tool can rapidly identify areas within VT isthmuses from substrate maps. Thirty patients with structural cardiomyopathy in whom a complete right ventricular-paced substrate map and a full reconstruction of the diastolic isthmus during VT could be obtained were enrolled. The VT isthmus border was projected on each substrate map to verify whether the areas illuminated by Lumipoint fell within those borders. The behavior of the electrograms detected at the illuminated areas of the substrate maps was studied during a right ventricular drive train and extra stimulus protocol: if the near field potentials showed a delayed conduction after a single extra stimulus, defined as a minimum of 10 ms increase of the time interval between the far field and the near field activation measured during the drive train, the electrogram was said to have a "decremental" behavior. The logistic analysis showed that areas with fractionated electrograms illuminated by the Lumipoint software and showing the greatest decremental behavior fell within the VT isthmus borders (OR = 1.66, CI: 1.41-1.75, p<0.001; OR=1.57 CI: 1.32-1.72, p<0.001, respectively) with a sensitivity, specificity, and positive predictive value of 87%, 96%, and 97%, respectively. Fractionated electrograms illuminated by the automated Lumipoint software on right ventricular-paced substrate maps showing the greatest decremental behavior fall within the VT isthmus borders with a probability of 0.97, irrespective of their timing, annotation, or voltage, without any need for subjective assessment of their involvement in slow conduction areas.

Mental, physical, and phychophysiological responses to FFP2/N95 face mask during HIIT in active women.

Training systems based on high-intensity interval training (HIIT) have experienced great influence in recent years within the context of exercise and sport. This study aims to provide insight on whether the immediate outcomes (e.g., central and peripheral acute responses) may be intensified or attenuated when a HIIT protocol is performed using a FFP2/N95 face mask in active healthy adult women. In other words, it strives to provide new findings relative to the use of face masks as a potential performance enhancing tool. In the current study, the same training session was carried out on two occasions under different conditions (i.e., with FFP2/N95 and without FFP2/N95) in a cross-over experimental design. The following study variables were assessed before and after the HIIT in both sessions: Lactate, cortisol, alpha-amylase, selective attention, countermovement jump (CMJ), and power output. Additionally, central and peripheral Rates of Perceived Exertion (RPE) were assessed before and during the HIIT. This study makes novel contributions to prior research, showing that the use of FFP2/N95 face mask (vs. no mask) yielded higher alpha-amylase, selective attention, and peripheral RPE scores. No significant differences were found for lactate, cortisol, CMJ, and power output. Interestingly, central RPE scores were significantly lower under FFP2/N95 face mask (vs. no mask) condition. The main suggestion in light of these results is that researchers and practitioners should consider potential peripheral and central responses to training stimuli when using FFP2/N95 face masks.

Model reduction for ‐induced vesicle fusion dynamics

AbstractIn this work, we adapt an established model for the ‐induced fusion dynamics of synaptic vesicles and employ a lumping method to reduce its complexity. In the reduced system, sequential ‐binding steps are merged to a single releasable state, while keeping the important dependence of the reaction rates on the local concentration. We examine the feasibility of this model reduction for a representative stimulus train over the physiologically relevant site‐channel distances. Our findings show that the approximation error is generally small and exhibits an interesting nonlinear and non‐monotonic behavior where it vanishes for very low distances and is insignificant at intermediary distances. Furthermore, we give expressions for the reduced model's reaction rates and suggest that our approach may be used to directly compute effective fusion rates for assessing the validity of a fusion model, thereby circumventing expensive simulations.

Click-train evoked steady state harmonic response as a novel pharmacodynamic biomarker of cortical oscillatory synchrony

Sensory networks naturally entrain to rhythmic stimuli like a click train delivered at a particular frequency. Such synchronization is integral to information processing, can be measured by electroencephalography (EEG) and is an accessible index of neural network function. Click trains evoke neural entrainment not only at the driving frequency (F), referred to as the auditory steady state response (ASSR), but also at its higher multiples called the steady state harmonic response (SSHR). Since harmonics play an important and non-redundant role in acoustic information processing, we hypothesized that SSHR may differ from ASSR in presentation and pharmacological sensitivity. In female SD rats, a 2 s-long train stimulus was used to evoke ASSR at 20 Hz and its SSHR at 40, 60 and 80 Hz, recorded from a prefrontal epidural electrode. Narrow band evoked responses were evident at all frequencies; signal power was strongest at 20 Hz while phase synchrony was strongest at 80 Hz. SSHR at 40 Hz took the longest time (∼180 ms from stimulus onset) to establish synchrony. The NMDA antagonist MK801 (0.025–0.1 mg/kg) did not consistently affect 20 Hz ASSR phase synchrony but robustly and dose-dependently attenuated synchrony of all SSHR. Evoked power was attenuated by MK801 at 20 Hz ASSR and 40 Hz SSHR only. Thus, presentation as well as pharmacological sensitivity distinguished SSHR from ASSR, making them non-redundant markers of cortical network function. SSHR is a novel and promising translational biomarker of cortical oscillatory dynamics that may have important applications in CNS drug development and personalized medicine.

Time-Saving Versus Time-Efficient Training Terminology, Methods, and Prescription

ABSTRACT A common obstacle to achieving recommended physical activity and desired training goals is time. This is true for recreationally trained adults and athletes, particularly at the collegiate level, where greater restrictions on practice time and training are in place. One possible solution is to implement time-saving and time-efficient training routines and methods that may limit the amount of time needed to attain desired physiological adaptations—by decreasing the time needed to train and/or by increasing the frequency with which brief workouts are completed throughout the week (e.g., “microdosing”). To provide the most optimal training stimulus, the correct method must be used. Unfortunately, numerous terms describe routines and methods discussed in the current body of available literature, many of which may seem similar and lead to confusion. The purpose of this article is to outline the similarities and differences of the numerous time-saving and time-efficient training routines and methods. Ultimately, this article synthesizes the current research into practical recommendations as programming options for strength and conditioning coaches and personal trainers. The information provided may also serve as a foundation for future research opportunities in time-saving and time-efficient training.

Doping-modulated lateral asymmetric Schottky diode as a high-performance self-powered synaptic device.

In the post-Moore era, the gradually saturated computational capability of conventional digital computers showing the opposite trend as the exponentially increasing data volumes imperatively required a platform or technology to break this bottleneck. Brain-inspired neuromorphic computing promises to inherently improve the efficiency of information processing and computation by means of the highly parallel hardware architecture to reduce global data transmission. Here, we demonstrate a compact device technology based on the barrier asymmetry to achieve zero-consumption self-powered synaptic devices. In order to tune the device behaviors, the typical chemical doping is used to tailor the asymmetry for energy harvesting. Finally, in our demonstrated devices, the open-circuit voltage (VOC) and power-conversion efficiency (PCE) can be modulated up to 0.77 V and 6%, respectively. Optimized photovoltaic features affords synaptic devices with an outstanding programming weight states, involving training facilitation, stimulus reinforce and consolidation. Based on self-powered system, this work further presents a highly available modulation scheme, which achieves excellent device behaviors while ensuring the zero-energy consumption.

The Emerging Role of Hypoxic Training for the Equine Athlete.

This paper provides a comprehensive discussion on the physiological impacts of hypoxic training, its benefits to endurance performance, and a rationale for utilizing it to improve performance in the equine athlete. All exercise-induced training adaptations are governed by genetics. Exercise prescriptions can be tailored to elicit the desired physiological adaptations. Although the application of hypoxic stimuli on its own is not ideal to promote favorable molecular responses, exercise training under hypoxic conditions provides an optimal environment for maximizing physiological adaptations to enhance endurance performance. The combination of exercise training and hypoxia increases the activity of the hypoxia-inducible factor (HIF) pathway compared to training under normoxic conditions. Hypoxia-inducible factor-1 alpha (HIF-1α) is known as a master regulator of the expression of genes since over 100 genes are responsive to HIF-1α. For instance, HIF-1-inducible genes include those critical to erythropoiesis, angiogenesis, glucose metabolism, mitochondrial biogenesis, and glucose transport, all of which are intergral in physiological adaptations for endurance performance. Further, hypoxic training could conceivably have a role in equine rehabilitation when high-impact training is contraindicated but a quality training stimulus is desired. This is achievable through purpose-built equine motorized treadmills inside commercial hypoxic chambers.

What do our sampling assumptions affect: How we encode data or how we reason from it?

In describing how people generalize from observed samples of data to novel cases, theories of inductive inference have emphasized the learner's reliance on the contents of the sample. More recently, a growing body of literature suggests that different assumptions about how a data sample was generated can lead the learner to draw qualitatively distinct inferences on the basis of the same observations. Yet, relatively little is known about how and when these two sources of evidence are combined. Do sampling assumptions affect how the sample contents are encoded, or is any influence exerted only at the point of retrieval when a decision is to be made? We report two experiments aimed at exploring this issue. By systematically varying both the sampling cover story and whether it is given before or after the training stimuli we are able to determine whether encoding or retrieval issues drive the impact of sampling assumptions. We find that the sampling cover story affects generalization when it is presented before the training stimuli, but not after, which suggests that sampling assumptions are integrated during encoding. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Acute work rate adjustments during high-intensity interval training in a hot and temperate environment.

Heart rate drifts upward over time during interval exercise and during exercise in hot conditions. As such, work rate must be lowered to maintain target heart rate. The purpose was to characterize acute work rate adjustments during high-intensity interval training based on target heart rate. Seven humans (three females) completed five study visits: a graded exercise test on a cycle ergometer to measure maximal heart rate (HRmax) in ∼22°C and four trials performed in ∼22°C (TEMP) or ∼35°C (HOT), consisting of an 8 min warm-up at 70% HRmax followed by one (15TEMP and 15HOT) or five (43TEMP and 43HOT) rounds of high-intensity interval training (one round = 4min work at 90% HRmax and 3min recovery at 70% HRmax) totaling 15min or 43min of exercise, respectively. Work rate was lowered 33 ± 20W (p=0.005) in 43TEMP and 56 ± 30W (p=0.003) in 43HOT between the first and fifth work intervals. Thermal strain (0.2°C higher rectal temperature, p=0.01) and cardiovascular strain (6 beats·min-1 larger increase in heart rate from first to fifth recovery interval, p=0.01) were greater in 43HOT versus 43TEMP. Using target heart rate during high-intensity interval training may reduce the training stimulus, especially in hot environments, but it may also limit thermal strain and enable participants to complete the prescribed workout despite the heat.

Comparison of Traditional and Advanced Resistance Training Paradigms on Muscle Hypertrophy in Trained Individuals: A Systematic Review and Meta-Analysis.

Trained individuals may require variations in training stimuli and advanced resistance training paradigms (ADV) to increase skeletal muscle hypertrophy. However, no meta-analysis has examined how ADV versus traditional (TRAD) approaches may differentially affect hypertrophic outcomes in trained populations. The aim of this review was to determine whether the skeletal muscle hypertrophy responses induced by TRAD differed from ADV in resistance-trained individuals. Furthermore, we sought to examine potential effects of dietary factors, participants' training status, and training loads. We searched for peer-reviewed, randomized controlled trials (published in English) conducted in healthy resistance-trained adults performing a period of TRAD and ADV with pre-to-post measurement(s) of muscle hypertrophy in PubMed, Web of Science, SPORTDiscus, and MEDLINE databases up to October 2022. A formal meta-analysis was conducted in Revman5, and risk of bias was assessed by ROB2. Ten studies met the inclusion criteria. Results indicated no difference between ADV and TRAD for muscle thickness (SMD = 0.05, 95% CI: -0.20 0.29, p = 0.70), lean mass (SMD = -0.01, 95% CI: -0.26 0.23, p = 0.92), muscle cross-sectional area (SMD = -0.07, 95% CI: -0.36 0.22, p = 0.64), or all measurements analyzed together (SMD = -0.00, 95% CI: -0.15 0.14, p = 0.95). No heterogeneity or inconsistencies were observed; however, unclear risk of bias was present in most of the studies. Short-term ADV does not induce superior skeletal muscle hypertrophy responses when compared with TRAD in trained individuals. This review was not previously registered.

Serum brain-derived neurotrophic factor (BDNF) and self-paced time-trial performance in older untrained men.

This study examined the effect of 12 weeks of concurrent aerobic and resistance training on brain derived neurotrophic factor (BDNF) levels, neuromuscular performance and cerebral oxygenation on self-paced cycling exercise in previously untrained older men. Eight untrained healthy males aged 53-64 years performed a familiarisation and a pre-training self-paced cycling time trial before 12 weeks of exercise training which combined aerobic and resistance exercise. The self-paced cycling time trial comprised a 30 s maximal effort sprint for every 4.5 min of lower intensity pace for a total of 25 min. Upon completion of 12 weeks of training, a comparison of the pre-training trial analysed for serum BDNF, neuromuscular performance, and cerebral oxygenation was undertaken. Serum BDNF decreased significantly from 10.02 ± 4.63 to 6.96 ± 3.56 ng/ml after 12 weeks of training. There was also attenuated physiological strain for a comparable self-paced cycling performance. Despite positive physiological responses during the time trial pacing strategy was not altered compared with pre training. BDNF decreases following 12 weeks of concurrent training and might reflect neuroplasticity for this type of training stimulus. Exercise training in previously sedentary older men can result in a multitude of physical benefits, which may also confer a neuroprotective effect. However, specific training is required to improve pacing strategies in previously untrained older males. Australian New Zealand Clinical Trials Registry number ACTRN12622001477718.