Objective To observe the application effect of simple respirator combined with respiratory function training in airway management of patients with cerebral apoplexy after tracheotomy. Methods Totally 93 patients with stroke tracheotomy from May 2017 to April 2018 were randomly divided into the intervention group (45 cases) and thecontrol group (48 cases). The control group was treated with routine nursing after tracheotomy, and the intervention group was trained by simple ventilator combined with breathing function on the basis of the control group.The incidence of pulmonary infection during the tracheal cannula in two groups was observed, the total retention time of the trachea cannula, the incidence of blood oxygen saturation < 94% from 24 h to 48 h, the number of cases of catheterization, and the incidence of pulmonary infection were observed. Results In the intervention group and the control group, the pulmonary infection rate was 6.67% (3/45) in the intervention group, which was lower than the control group. The lung infection rate was 20.83% (10/48). The significance of learning (χ2=3.89, P=0.04); the total indwelling time of tracheal intubation in the intervention group (25.73±6.51) d was shorter than that in the control group (28.28±4.79) d, the difference was statistically significant (t=-2.16, P=0.03); within the intervention group and the control group, within 24-48 hours, the oxygen saturation of the intervention group was <0.94 (6.6% (3/45), and the incidence of pulmonary infection was 2.22% (1/45). The incidence rate of re-intubation was 0 (0/45), which was lower than 22.92% (11/48), 14.58% (7/48), and 10.42% (5/48) of the control group. The difference was statistically significant (χ2= 4.80, 4.51, 4.75, P= 0.03, 0.03, 0.03). Conclusions The simple breathing apparatus combined with respiratory function training can effectively improve the respiratory function of the patients, reduce the occurrence of pulmonary infection and re tube after the tracheal tubing and tubing, shorten the retention time of the trachea cannula, reduce the patient's pain and economic burden, and reduce the risk of nursing. It is scientific and effective. Airway management measures should be widely applied in clinical practice. Key words: Stroke; Tracheotomy; Simple respirator; Respiratory function training; Nursing care